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The combined effects of ocean warming and ocean acidification on Pacific cod (Gadus macrocephalus) early life stages
The eastern North Pacific is simultaneously experiencing ocean warming (OW) and ocean acidification (OA), which may negatively affect fish early life...
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Seed priming with melatonin improved salinity tolerance of halophytes during early life-cycle stages
Melatonin ( MT ) is a tryptophan derivative with multiple functions in both animals and plants. Exogenously-provided MT such as through seed priming...
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TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
Environmental exposure to endocrine-disrupting chemicals (EDCs) is linked to the development of uterine fibroids (UFs) in women. UFs, non-cancerous...
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Genes possibly related to symbiosis in early life stages of Acropora tenuis inoculated with Symbiodinium microadriaticum
Due to the ecological importance of mutualism between reef-building corals and symbiotic algae (Family Symbiodiniaceae), various transcriptomic...
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Early life history affects fish size mainly by indirectly regulating the growth during each stage: a case study in a demersal fish
The complex life histories of demersal fishes are artificially separated into multiple stages along with changes in morphology and habitat. It is...
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Evidence from Finland and Sweden on the relationship between early-life diseases and lifetime childlessness in men and women
The percentage of people without children over their lifetime is approximately 25% in men and 20% in women. Individual diseases have been linked to...
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Life History and Early Development of Fishes
The study of life history of fish is one of the important contents of fishery biology. The life history of fish refers to the life course of...
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Temporal dynamics of the fecal microbiome in female pigs from early life through estrus, parturition, and weaning of the first litter of piglets
BackgroundAge-associated changes in the gastrointestinal microbiome of young pigs have been robustly described; however, the temporal dynamics of the...
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Transmission of fungi and protozoa under grazing conditions from lactating yaks to sucking yak calves in early life
AbstractMicrobiota from mothers is an essential source of microbes in early-life rumen microbiota, but the contribution of microbiota from different...
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Environmental Conditions in Early Life, Host Defenses, and Disease in Late Life
Immunity is an essential function for host homeostasis through its action on the control of pathogenic organisms and malignant cells. Immune defenses...
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Unveiling the early life core microbiome of the sea cucumber Apostichopus japonicus and the unexpected abundance of the growth-promoting Sulfitobacter
BackgroundMicrobiome in early life has long-term effects on the host’s immunological and physiological development and its disturbance is known to...
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The early-life exposome modulates the effect of polymorphic inversions on DNA methylation
Polymorphic genomic inversions are chromosomal variants with intrinsic variability that play important roles in evolution, environmental adaptation,...
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Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation
Aerobic exercise is well known to promote neuroplasticity and hippocampal memory. In the develo** brain, early-life exercise (ELE) can lead to...
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Genomic Risk for Schizophrenia, the Early Life Environment, and the Room Left for Developmental Epigenetic Plasticity
Most individuals with genomic risk for schizophrenia do not develop the disorder, suggesting that the path that goes from genetic susceptibility to...
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Early life changes in histone landscape protect against age-associated amyloid toxicities through HSF-1-dependent regulation of lipid metabolism
Transient events during development can exert long-lasting effects on organismal lifespan. Here we demonstrate that exposure of Caenorhabditis elegans ...
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Early Life Nutrition and the Programming of the Phenotype
Early developmental nutrition profoundly influences phenotypic trajectories and affects adult morphology, physiology, behaviour, longevity and...
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Early-life viral infections are associated with disadvantageous immune and microbiota profiles and recurrent respiratory infections
The respiratory tract is populated by a specialized microbial ecosystem, which is seeded during and directly following birth. Perturbed development...
