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Gene Co-expression Network Analysis to Mine Genes Involved in Plant Secondary Metabolite Biosynthesis and Regulation
Plants produce diverse specialized metabolites (SMs) that do not participate in plant growth and development but help them adapt to various... -
Quorum quenchers affect the virulence regulation of non-mucoid, mucoid and heavily mucoid biofilms co-cultured on cell lines
Biofilm formation conferring pathogenicity is a survival strategy for Pseudomonas aeruginosa . P. aeruginosa ’s virulence may differ due to differences...
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Regulation of CO2 fluxes along gradients of water saturation in irrigation canal sediments
Hydrological intermittency affects sediment biogeochemistry, organic carbon (OC) metabolism and carbon dioxide (CO 2 ) emission but the study of the...
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Delineating the mechanisms of elevated CO2 mediated growth, stress tolerance and phytohormonal regulation in plants
Global climate change has drastically affected natural ecosystems and crop productivity. Among several factors of global climate change, CO 2 is...
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Deciphering the biochemical regulation of metabolic pathways in abating stress-induced damages during co-exposure of arsenic and fluoride in a non-aromatic and an aromatic rice variety
The aim of the current work was to decipher the systemic damage and biochemical defense machinery due to combined arsenic (5 mg L −1 Na 3 AsO 4 ) and...
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DiNeR: a
Di fferential graphical model for analysis of co-regulationNe tworkR ewiringBackgroundDuring transcription, numerous transcription factors (TFs) bind to targets in a highly coordinated manner to control the gene expression....
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Co-expression network analysis uncovers key candidate genes related to the regulation of volatile esters accumulation in Woodland strawberry
Main conclusionFveERF (FvH4_5g04470.1), FveAP2 (FvH4_1g16370.1) and FveWRKY (FvH4_6g42870.1) might be involved in fruit maturation of strawberry....
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Co-regulation map of the human proteome enables identification of protein functions
Assigning functions to the vast array of proteins present in eukaryotic cells remains challenging. To identify relationships between proteins, and...
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Co-action of ABA, brassinosteriod hormone pathways and differential regulation of different transcript isoforms during cold-and-dark induced senescence in Arabidopsis
Senescence in nature is augmented by multiple abiotic factors such as aging, cold and dark simultaneously. To identify unique components involved in...
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Co-regulation Role of Endogenous Hormones and Transcriptomics Profiling Under Cold Stress in Tetrastigma hemsleyanum
Tetrastigma hemsleyanum Diels et Gilg is a valuable medicinal herb. Chilling sensitivity is the major limiting factor of the artificial cultivation...
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Co-regulation of Auxin and Cytokinin in Anthocyanin Accumulation During Natural Development of Purple Wheat Grains
Purple-colored wheat is a kind of wheat with purple-colored grains that contain significant levels of anthocyanins, and anthocyanins benefit human...
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Identification of Plant Co-regulatory Modules Using CoReg
Regulatory network is often characterized by complex interactions between transcription factors (TFs) and target genes. The synergistic regulations... -
Impact of Co-chaperones and Posttranslational Modifications Toward Hsp90 Drug Sensitivity
Posttranslational modifications (PTMs) regulate myriad cellular processes by modulating protein function and protein-protein interaction. Heat shock... -
Flowering onset time is regulated by microRNA-mediated trehalose-6-phosphate signaling in Cajanus cajan L. under elevated CO2
CO 2 levels are known to have an impact on plant development and physiology. In the current study, we have investigated the effect of elevated CO 2 on...
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Characterizing Post-transcriptional Modifications of circRNAs to Investigate Biogenesis and Translation
Recent studies have shown that circular RNAs (circRNAs) are decorated with N6-methyladenosine (m6A), a co-transcriptional modification known to... -
Density regulation of co-occurring herbivores via two indirect effects mediated by biomass and non-specific induced plant defenses
Two herbivorous species that share a single plant can interact indirectly with one another, even without direct interaction. One type of indirect...
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Cdc37 as a Co-chaperone to Hsp90
The co-chaperone p50/Cdc37 is an important partner for Hsp90, assisting in molecular chaperone activities, particularly with regard to the regulation... -
Targeting Transcription Factors in Cancer: From “Undruggable” to “Druggable”
Deregulation of transcription factors is critical to hallmarks of cancer. Genetic mutations, gene fusions, amplifications or deletions, epigenetic... -
Identification of co-expressed genes and immune infiltration features related to the progression of atherosclerosis
Atherosclerosis is a chronic inflammatory disease that affects arterial walls and is a leading cause of cardiovascular disease. Gene co-expression...
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Regulation of Notch signaling by non-muscle myosin II Zipper in Drosophila
The Notch pathway is an evolutionarily conserved signaling system that is intricately regulated at multiple levels and it influences different...