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Stem Cell Niche in the Mammalian Carotid Body
Accumulating evidence suggests that the mammalian carotid body (CB) constitutes a neurogenic center that contains a functionally active germinal...
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Cell Cycle Regulation in Mammalian Germ Cells
Meiosis is a unique form of cellular division by which a diploid cell produces genetically distinct haploid gametes. Initiation and regulation of...
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Application of Single-Cell Sequencing on Stem Cell Research
The variation and heterogeneity within cells are the fundamental features of stem cells. Each tissue has a resident stem cell niche compartmentalized...
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The Epiblast and Pluripotent Stem Cell Lines
All somatic cells develop from the epiblast, which occupies the upper layer of two-layered embryos and in most mammals is formed after the...
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Stem Cell Culture Techniques
Stem cell culture is a crucial cell culture technique that involves diverse disciplines such as modern biotechnology. It is mainly used in the area...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Stem Cells as Nuclear Donors for Mammalian Cloning
Mammals are routinely cloned by introducing somatic nuclei into enucleated oocytes. Cloning contributes to propagating desired animals, to germplasm...
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Application of Single-Cell Sequencing on Stem Cell Research
The variation and heterogeneity within cells are the fundamental features of stem cells. Each tissue has a resident stem cell niche compartmentalized...
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Stem Cell-Based Regenerative Medicine Therapy in Cancer
Stem cells play a unique role in various stages of an organism’s life cycle. Intensive research on the biology of stem cells has demystified many...
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Stem Cell Bioreactors: Design, Structure, and Operation of Stem Cell Bioreactors
A bioreactor is a manufactured device or system that helps to produce biologically active substances such as yeast, bacteria, or mammalian cells...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Germline Stem Cell Technology in Fertility Preservation
Recent germline stem cell technology advancements paved the foundation for treating infertility and making amenable progress in the resurrection of...
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Challenges and perspectives of heart repair with pluripotent stem cell-derived cardiomyocytes
Here we aim at providing a concise but comprehensive overview of the perspectives and challenges of heart repair with pluripotent stem cell-derived...
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Imaging and Analysis of Drosophila Neural Stem Cell Asymmetric Division
Cell divisionCell division is a conserved process among eukaryotes. It is designed to segregate chromosomes into future daughter cells and involves a...
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Early Cell Specification in Mammalian Fertilized and Somatic Cell Nuclear Transfer Embryos
Early cell specification in mammalian preimplantation embryos is an intricate cellular process that leads to coordinated spatial and temporal...
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Local and systemic mechanisms that control the hair follicle stem cell niche
Hair follicles are essential appendages of the mammalian skin, as hair performs vital functions of protection, thermoregulation and sensation. Hair...
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Stem Cell-Based Therapeutic Approaches in Genetic Diseases
Stem cells, which can self-renew and differentiate into different cell types, have become the keystone of regenerative medicine due to these...
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Viral Transduction of Mammalian Spermatogonial Stem Cells
Lentiviral vectors have been major tools for genetic manipulation of spermatogonial stem cells (SSCs) in vitro. Adeno-associated viral vectors are...
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Stem Cell Applications in Cardiac Tissue Regeneration
Cardiovascular pathologies are the leading cause of morbidity and mortality worldwide. While heart transplant remains the gold standard, it is...
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Stem Cell-Based Regenerative Medicine Therapy in Cancer
Stem cells play a unique role in various stages of an organism’s life cycle. Intensive research on the biology of stem cells has demystified many...