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Primer extension refractory PCR: an efficient and reliable genome walking method
Genome walking, a molecular technique for obtaining unknown flanking genomic sequences from a known genomic sequence, has been broadly applied to...
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Crucifer’s Pathogens Genome
The information on genome sequences, analysis and assembly of limited pathogens of crucifers has been generated and made available. It has given... -
The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms
Physical activity, including walking, has numerous health benefits in older adults, supported by a plethora of observational and interventional...
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Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival
Walking is a simple form of exercise, widely promoted for its health benefits. Self-reported walking pace has been associated with a range of...
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Diospyros Lotus Genome
Crop genomics and genetics have been radically progressed in this past decade, as a whole genome-wide sequencing era. Notwithstanding, it is still... -
Investigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length
Walking pace is a simple and functional form of movement and a strong predictor of health status, but the nature of its association with leucocyte...
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The genome of the filamentous fungus Ashbya gossypii: annotation and evolutionary implications
The 9.2 Mb genome of the filamentous fungus Ashbya gossypii consists of seven chromosomes carrying 4718 protein coding genes, 194 tRNA genes, at... -
Genome-Wide Prediction of Disease Resistance Gene Analogs in Flax
Flax (Linum usitatissimum L.) is an important crop as the sources of fiber and seed oil. Annually, various pathogens cause significant loss to flax... -
Jute Genome Sequencing: A Bangladeshi Initiative
Jute is the second most abundant natural source of bio-based fiber after cotton. This fiber, known to have high tensile strength, is non-abrasive in... -
A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals
Sarcopenia is a common skeletal muscle disease in older people. Lower limb muscle strength is a good predictive value for sarcopenia; however, little...
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Genome-wide association study of musical beat synchronization demonstrates high polygenicity
Moving in synchrony to the beat is a fundamental component of musicality. Here we conducted a genome-wide association study to identify common...
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De Novo Assembly and Annotation of the Siganus fuscescens (Houttuyn, 1782) Genome: Marking a Pioneering Advance for the Siganidae Family
This study presents the first draft genome of Siganus fuscescens , and thereby establishes the first whole-genome sequence for a species in the...
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Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging
The concept of aging is complex, including many related phenotypes such as healthspan, lifespan, extreme longevity, frailty and epigenetic aging,...
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A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
Frailty is an aging-related clinical phenotype defined as a state in which there is an increase in a person’s vulnerability for dependency and/or...
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Genome-wide identification and analysis of a cotton secretome reveals its role in resistance against Verticillium dahliae
BackgroundThe extracellular space between the cell wall and plasma membrane is a battlefield in plant-pathogen interactions. Within this space, the...
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A paired-end whole-genome sequencing approach enables comprehensive characterization of transgene integration in rice
Efficient, accurate molecular characterization of genetically modified (GM) organisms is challenging, especially for those transgenic events...
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Complete genome analysis of pathogenic Metschnikowia bicuspidata strain MQ2101 isolated from diseased ridgetail white prawn, Exopalaemon carinicauda
BackgroundMetschnikowia bicuspidata is a pathogenic yesst that can cause disease in many different economic aquatic animal species. In recent years,...
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Haplotype-resolved assembly of a pig genome using single-sperm sequencing
Single gamete cell sequencing together with long-read sequencing can reliably produce chromosome-level phased genomes. In this study, we employed...
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Amplicon genome fishing (AGF): a rapid and efficient method for sequencing target cis-regulatory regions in nonmodel organisms
Cis -regulatory sequences play a crucial role in regulating gene expression and are evolutionary hot spots that drive phenotypic divergence among...
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A Century of Cytogenetic and Genome Analysis: Impact on Wheat Crop Improvement
Beginning in the first decade of 1900, pioneering research in disease resistance and seed color inheritance established the scientific basis of...