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AZD2014, a dual mTOR inhibitor, attenuates cardiac hypertrophy in vitro and in vivo
Cardiac hypertrophy is one of the most common genetic heart disorders and considered a risk factor for cardiac morbidity and mortality. The mammalian...
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Effect of different degrees of adenoid hypertrophy on pediatric upper airway aerodynamics: a computational fluid dynamics study
To improve the diagnostic accuracy of adenoid hypertrophy (AH) in children and prevent further complications in time, it is important to study and...
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Electro-Mechanical Finite Element Model of Left Ventricular Hypertrophy
Left ventricular hypertrophy (LVH) is one of the common heart diseases that contribute to global morbidity and mortality. LVH can be further...
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Wall Stress Analysis of Patient-Specific Left Ventricular Hypertrophy Models
Left ventricular hypertrophy (LVH) is a complex heart disease characterised by abnormal heart wall. A wall stress analysis may provide insight on...
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A multiscale model of cardiac concentric hypertrophy incorporating both mechanical and hormonal drivers of growth
Growth and remodeling in the heart is driven by a combination of mechanical and hormonal signals that produce different patterns of growth in...
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A deep neural network electrocardiogram analysis framework for left ventricular hypertrophy prediction
Heart disease is ranked second in the top ten death causes in Taiwan in 2016, while the amount of heart disease fatalities is increasing by about 700...
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Predictions of hypertrophy and its regression in response to pressure overload
Mechanics-based cardiac growth models can now predict changes in mass, chamber size, and wall thickness in response to perturbations such as pressure...
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Solving the Problem of Diagnosing a Disease by ECG on the PTB-XL Dataset Using Deep Learning
Diagnosis by electrocardiogram (ECG) is an extremely urgent and important task, the quality, timeliness and speed of which people’s lives and health...
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Simulating impaired left ventricular–arterial coupling in aging and disease: a systematic review
Aortic stenosis, hypertension, and left ventricular hypertrophy often coexist in the elderly, causing a detrimental mismatch in coupling between the...
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Numerical study of the effect of nasopharynx airway obstruction on the transport and deposition of nanoparticles in nasal airways
Although there is abundant literature for both experimental and numerical studies of respiratory aerosol exposure in nasal airways, research efforts...
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Muscle Strength Determinants and Physiological Adaptations
Strength training, also known as weight or resistance training (RT), has become one of the most popular forms of exercise, not only for sport...
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Stockwell Transform Based Time-Frequency Analysis of the ECG Features for Assessment of Risk of Left Ventricular Hypertrophy in Hypertension Patients
Hypertension is a major disease that affects millions of people world-wide. If hypertension remains untreated for long time it could give rise to an...
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Construct Left Ventricular Hypertrophy Prediction Model Based on Random Forest
Heart disease ranks second in Taiwan’s top ten cause of death in 2016 and the number of deaths in heart disease increases by about 700 people each...
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The Fusion Model of ResNet and GRU Based on Simplified Self-Attention for ECG Classification on PTB-XL Dataset
The electrocardiogram (ECG) depicts the orderly depolarization process of the pacemaker, atria and ventricles during each cardiac cycle. Waveforms...
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Assessment of LV Myocardial Function in Aortic Stenosis Using Personalized 3D+ Time Cardiac MRI Modelling
Left ventricular hypertrophy (LVH) in aortic stenosis (AS) is known as an adaptive response affected by pressure overload as a result of the...
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Multiscale model of heart growth during pregnancy: integrating mechanical and hormonal signaling
Pregnancy stands at the interface of mechanics and biology. The growing fetus continuously loads the maternal organs as circulating hormone levels...
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The influence of boundary conditions and protein availability on the remodeling of cardiomyocytes
The heart muscle is capable of growing and remodeling in response to changes in its mechanical and hormonal environment. While this capability is...
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Design and Simulation of ECG Signal Generator by Making Use of Medical Datasets and Fourier Transform for Various Arrhythmias
The activities of human heart are summarized using electrocardiogram which provides electrical changes occurring on human body. The noninvasive...
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Supplementation and Ergogenic Aids for Enhancing Muscular Strength Production
This chapter presents two essential premises to abolish the classic bilateral relationship between nutrition and strength: the relationship of...
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The Importance of Genetic and Clinical Data Features in Risk Stratification of Patients with Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy is a genetic cardiovascular disease which affects the heart’s left ventricle. This paper presents the results obtained...