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Comparative cell viability of dentin-bonding adhesive systems on human dental pulp stem cells: time-dependent analysis
BackgroundRestorative materials are in prolonged contact with living tissues such as oral mucosa, dentin, pulp, periodontal, and periapical tissues....
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Decellularized human amniotic membrane scaffolds: influence on the biological behavior of dental pulp stem cells
ObjectiveThe objective of this study was to assess the characterization of human acellular amniotic membrane (HAAM) using various decellularization...
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METTL3 promotes immature dental pulp stem cells-induced angiogenesis by regulating ETS1 mRNA stability in an m6A-HuR-dependent manner
Angiogenesis serves as the determinate element of pulp regeneration. Dental pulp stem cell (DPSC) implantation can promote the regeneration of dental...
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Extracellular matrix remodelling in dental pulp tissue of carious human teeth through the prism of single-cell RNA sequencing
Carious lesions are bacteria-caused destructions of the mineralised dental tissues, marked by the simultaneous activation of immune responses and...
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KAT2A-mediated succinylation modification of notch1 promotes the proliferation and differentiation of dental pulp stem cells by activating notch pathway
BackgroundDental pulp stem cells (DPSCs) are a kind of undifferentiated dental mesenchymal stem cells with strong self-renewal ability and...
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TNF-α, IL-1B and IL-6 affect the differentiation ability of dental pulp stem cells
BackgroundThis in vitro study examined the effect of the inflammatory cytokines (tumour necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6) on...
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Lin28 affects the proliferation and osteogenic differentiation of human dental pulp stem cells by directly inhibiting let-7b maturation
ObjectiveActivation of Lin28 gene under certain conditions promotes tissue damage repair. However, it remains unknown whether conditional expression...
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Comparison of cytotoxic and apoptosis-inducing effects of MTA, propolis, and propolis-MTA on immature dental pulp stem cells
BackgroundPulpotomy is a treatment option for the preservation of pulp vitality in primary teeth with extensive caries. Propolis is a natural...
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Human dental pulp stem cells mitigate the neuropathology and cognitive decline via AKT-GSK3β-Nrf2 pathways in Alzheimer’s disease
Oxidative stress is increasingly recognized as a major contributor to the pathophysiology of Alzheimer’s disease (AD), particularly in the early...
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BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells
BackgroundThe preservation of biological and physiological vitality as well as the formation of dentin are among the main tasks of human dental pulp...
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Dental pulp stem cells as a promising model to study imprinting diseases
Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting...
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Comparative proteomic analysis of dental pulp from supernumerary and normal permanent teeth
ObjectivesTo obtain and compare the protein profiles of supernumerary and normal permanent dental pulp tissues.
Materials and methods ...
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The regenerative potential of Tideglusib and CHIR99021 small molecules as potent odontogenic differentiation enhancers of human dental pulp stem cells
ObjectivesTo assess the effect of Tideglusib and CHIR99021 small molecules on the odontogenic differentiation potential of human dental pulp stem...
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Toll-like receptor and C-type lectin receptor agonists attenuate osteogenic differentiation in human dental pulp stem cells
BackgroundThis study aimed to investigate the effects of various toll-like receptor (TLR) and C-type lectin receptor (CLR) ligands on osteogenic...
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Human dental pulp stem cell responses to different dental pulp cap** materials
BackgroundDirect pulp cap** is a vital pulp therapy for a pin-point dental pulp exposure. Applying a pulp cap** material leads to the formation...
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Single-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capacity
Human dental pulp stem cells (hDPSCs) are easily obtained multipotent cells, however, their potential value in regenerative medicine is hindered by...
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Pulp Response to Clinical Procedures and Dental Materials
This chapter aims to provide readers with reliable, evidence-based data obtained from laboratory studies and clinical trials performed in the last...
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Preparation of PDA-GO/CS composite scaffold and its effects on the biological properties of human dental pulp stem cells
Reduced graphene oxide (rGO) is an graphene oxide (GO) derivative of graphene, which has a large specific surface area and exhibited satisfactory...
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Effect of graphene oxide/ poly-L-lactic acid composite scaffold on the biological properties of human dental pulp stem cells
BackgroundTissue engineering has attracted recent attention as a promising bone repair and reconstruction approach. Dental pulp stem cells (DPSCs)...
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The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells
BackgroundFacial nerve injury often results in poor prognosis due to the challenging process of nerve regeneration. Neuregulin-1, a human calmodulin,...
