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Promising applications of human-derived saliva biomarker testing in clinical diagnostics
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness in substances, and the huge amount. Due to its...
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RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma
ObjectiveHead and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that originates from the squamous cells. The role of the replication...
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MicroRNA‐155 (miR-155) as an accurate biomarker of periodontal status and coronary heart disease severity: a case–control study
BackgroundIncreasing evidence supports associations between periodontal disease and coronary heart disease (CHD). This case–control study evaluated...
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Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland
BackgroundThe diagnosis of sialadenitis, the most frequent disease of the salivary glands, is challenging when the symptoms are mild. In such cases,...
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CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma
BackgroundHead and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high...
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Serum biomarker levels in smokers and non-smokers following periodontal therapy. A prospective cohort study
BackgroundTo compare presence and levels of serum cytokines in smokers and non-smokers with periodontitis following periodontal therapy.
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MicroRNA expression as a prognostic biomarker of tongue squamous cell carcinoma (TSCC): a systematic review and meta-analysis
BackgroundRecent studies have indicated that microRNA (miRNA) expression in tumour tissues has prognostic significance in Tongue squamous cell...
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CERCAM is a prognostic biomarker associated with immune infiltration of macrophage M2 polarization in head and neck squamous carcinoma
PurposeThis study aimed to investigate the relevance of cerebral endothelial cell adhesion molecule (CERCAM) expression to head and neck squamous...
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Salivary IL-8 as a putative predictive biomarker of radiotherapy response in head and neck cancer patients
ObjectivesIonizing radiation increases the expression of a number of salivary proteins involved in immunoregulatory networks related to infection,...
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Diagnostic biomarker candidates for pulpitis revealed by bioinformatics analysis of merged microarray gene expression datasets
BackgroundPulpitis is an inflammatory disease, the grade of which is classified according to the level of inflammation. Traditional methods of...
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Correlation of molecular biomarker concentrations between synovial fluid and saliva of the patients with temporomandibular disorders
ObjectivesThe synovial membrane and fluid are involved in the pathogenesis of temporomandibular joint (TMJ) disorders. This study aims to assess the...
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Gingival crevicular fluid levels of apelin correlates with clinical periodontal diagnosis
ObjectivesLimitations of clinical periodontal measurements have led to the search for reliable biomarkers that can be used in diagnosis and...
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STAT1: a novel candidate biomarker and potential therapeutic target of the recurrent aphthous stomatitis
BackgroundThe recurrent aphthous stomatitis (RAS) frequently affects patient quality of life as a result of long lasting and recurrent episodes of...
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Salivary macrophage chemokines as potential biomarkers of gingivitis
ObjectiveThe present study aimed to analyze the salivary levels of macrophage-activating factor (MAF), macrophage-chemotactic factor (MCF), and...
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Plasma neurological biomarkers as a measure of neurotoxicity in pediatric dental general anesthesia: a prospective observational feasibility study
PurposeNeurotoxicity concerns have been raised over general anesthesia and sedation medication use in children. Such concerns are largely based on...
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Diagnostic potential of endothelin-1 in peri-implant diseases: a cross-sectional study
PurposeThis study aimed to evaluate the potential of Endothelin-1 (ET-1), a peptide derived from vascular endothelial cells, as a biomarker for...
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Salivary and serum asprosin hormone levels in the 2018 EFP/AAP classification of periodontitis stages and body mass index status: a case-control study
ObjectivesA newly discovered adipokine known asprosin in serum and saliva in patients with periodontitis has not been explored. The aim of this study...
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A prognostic model for oral squamous cell carcinoma using 7 genes related to tumor mutational burden
BackgroundOral squamous cell carcinoma (OSCC) is a rising problem in global public health. The traditional physical and imageological examinations...
