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The effects of ketogenic and chitosan-based diets on submandibular salivary gland in rat model: a comparative histological study
ObjectiveThis study was carried out in the submandibular salivary glands (SSGs) of rats to demonstrate the effect of a ketogenic diet (KD) in...
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Oral pathogen aggravates atherosclerosis by inducing smooth muscle cell apoptosis and repressing macrophage efferocytosis
Periodontitis imparting the increased risk of atherosclerotic cardiovascular diseases is partially due to the immune subversion of the oral pathogen,...
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Biomarkers in Oral Submucous Fibrosis
Initiation and progression of oral submucous fibrosis (OSF) and its transformation to oral squamous cell carcinoma (OSCC) involve changes at the...
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Sema3A secreted by sensory nerve induces bone formation under mechanical loads
Bone formation and deposition are initiated by sensory nerve infiltration in adaptive bone remodeling. Here, we focused on the role of Semaphorin 3A...
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Fibrogenic Factors and Molecular Mechanisms
Transforming growth factor-β is the major factor that influences fibroblast activation, extracellular matrix production, and other aspects important...
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Management of atypical cellular angiofibroma arising in the oral cavity using Er, Cr: YSGG laser: a case report
PurposeCellular angiofibroma (CAF) is a rare mesenchymal neoplasm that usually arises in the genital region. It is comprised of cellular fibrous...
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Pediatric upper lip myopericytoma: a case report and comprehensive review
BackgroundMyopericytoma is a rare spindle cell tumor of mesenchymal origin, typically benign, characterized by concentric proliferation of tumor...
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Pathology of Oral Submucous Fibrosis
The oral mucosa exhibits a spectrum of histopathological changes in oral submucous fibrosis. Though the pathognomonic feature is fibrosis, a range of...
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Swelling over the Right Cheek: Pleomorphic Adenoma
Pleomorphic adenoma (PA) is the most common benign salivary gland tumour with parotid being the most frequently affected gland. It clinically...
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In Vivo and In Vitro Experimental Evidence
This chapter deals with experimental evidence of known risk factors in creating an environment conducive for the development of oral submucous...
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Temporal gene expression profiling during early-stage traumatic temporomandibular joint bony ankylosis in a sheep model
BackgroundInvestigating the molecular biology underpinning the early-stage of traumatic temporomandibular joint (TMJ) ankylosis is crucial for...
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Periodontitis exacerbates pulmonary hypertension by promoting IFNγ+ T cell infiltration in mice
Uncovering the risk factors of pulmonary hypertension and its mechanisms is crucial for the prevention and treatment of the disease. In the current...
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Myoepithelial Cell Function in Salivary Gland Physiology and Disease
Human salivary glands (SG) are essential exocrine organs that produce and secrete saliva into the oral cavity. Saliva performs a number of functions...
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Curcumin as a Chemopreventive Agent for Oral Submucous Fibrosis
It is well known that there are no efficacious prevention and treatment strategies available for OSF. However, accumulating line of evidence suggests...
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Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis
Oral submucous fibrosis (OSF) is an oral condition characterized by chronic progression, which may lead to the development of malignancy. Currently,...
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Genetic Aspects of Oral Submucous Fibrosis
Oral cancer is a multistep process which may be preceded by oral potentially malignant disorders (OPMDs), such as oral submucous fibrosis (OSF) [1]....
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Biological Events at the Interface Between the Radicular Part of a Dental Implant and Bone
The integration of the endosseous portion of a dental implant relies heavily on interactions in the implant microenvironment. A complex biological...
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Oral myopericytoma: a rare pediatric case report and a review of the literature
BackgroundMyopericytoma is a rare mesenchymal neoplasm with perivascular myoid differentiation that arises most commonly in middle adulthood. The...
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METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs
Bisphosphonate-related osteonecrosis of jaw (BRONJ) is characterized by impaired osteogenic differentiation of orofacial bone marrow stromal cells...
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Assessment of redox state and biochemical parameters of salivary glands in rats treated with anti-obesity drug sibutramine hydrochloride
ObjectivesTo investigate the effects of anti-obesity drug sibutramine hydrochloride (SB) on redox state and biochemical parameters in the salivary...
