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Enhancement of salt solubility in a PVDF-PEO-based solid blend polymer electrolyte by gamma irradiation: effects on ion dynamics and relaxation properties
The blend of solid polymer electrolyte (SPE) has drawn tremendous attention due to its applications in energy devices. SPE prepared from a mixture of...
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Solubility enhancement of β-ionone with lipidic, amphiphilic, and inclusion complex: extensive polymeric biomaterials to develop formulations for poorly soluble drugs
Combinatorial chemistry and drug design have produced more lipophilic, heavier, and less water soluble drugs in recent years. It is more difficult to...
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Acrylic co-polymer and organic acid-based press coated pulsatile tablet of nifedipine using 32 factorial design: use of novel solubilizer for solubility enhancement
Many diseases exhibit circadian fluctuation, including diabetes, asthma, rheumatoid arthritis, and hypertension. These disorders cannot be...
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Enhancement of supercritical carbon dioxide solubility models using molecular simulation data
Supercritical carbon dioxide (SC-CO 2 ) has been used in a broad range of industrial applications due to its unique properties, which underlines the...
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Solubility enhancement of indigo dye through biochemical reduction and structural modification
Indigo is one of the most widely used dyes for textiles and is thus produced in large quantities. Owing to its low solubility, a chemical-dependent...
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Research on Ternary Solid Dispersions of Celecoxib with Surfactant: Preparation, Characterization, and Solubility Property
AbstractCelecoxib (CXB) is a nonsteroidal anti-inflammatory drug (NSAID). However, the application of CXB has been compromised by its poor aqueous...
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Tagging Recombinant Proteins to Enhance Solubility and Aid Purification
Protein fusion technology has had a major impact on the efficient production and purification of individual recombinant proteins. The use of...
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Improved Solubility of Baclofen Using Suitable Coformers
This work presents the application of L-tartaric acid (L-TA), ascorbic acid (AA), and L-carnitine (L-CAR) as a safe and non-toxic alternative agent...
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Exploring the potential of surface-active copolymers on P123 micelles for drug solubility enhancement and in vitro cytotoxicity assay
This study presents the self-assembly of polyethylene oxide (PEO)- block -polypropylene oxide (PPO)- block -polyethylene oxide (PEO)-based block...
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Targeting Efficient Features of Urate Oxidase to Increase Its Solubility
With the demand for mass production of protein drugs, solubility has become a serious issue. Extrinsic and intrinsic factors both affect this...
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Solubility Measurement, Model Correlation, and Solvent Effect Analysis of Spectinomycin Dihydrochloride Pentahydrate in Three Binary Solvents
The solubility data of spectinomycin dihydrochloride pentahydrate (SDP) in three binary solvents were determined over a temperature range of...
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A new semi-empirical model for correlation of solubility of ligands in supercritical carbon dioxide
Model correlation of solubilities of task-specific ligands in supercritical carbon dioxide medium (SC-CO 2 ) plays an important role in development of...
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Effect of 2-hydroxyethylammonium carboxylate protic ionic liquids on the solubility and cytotoxicity of indomethacin
Recently, there is a particular interest to utilize protic ionic liquids (PILs) in drug solubility. This study is exploring the effect of three...
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The Modification of Dissolution Kinetics and Solubility of Lysozyme Crystals by Ionic Liquids
Knowing about the dissolution kinetics and solubility is necessary for controlling crystallization separation process of lysozyme. In this study, the...
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HybridGCN for protein solubility prediction with adaptive weighting of multiple features
The solubility of proteins stands as a pivotal factor in the realm of pharmaceutical research and production. Addressing the imperative to enhance...
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Solubility of Food-Relevant Substances in Pure and Modified Supercritical Carbon Dioxide: Experimental Data (2011–Present), Modeling, and Related Applications
For many high-pressure processes employing pressurized fluids, such as supercritical fluid extraction (SFE) of natural matrices with supercritical...
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Cubic plus association (CPA/qCPA) and classical thermodynamic modeling of pharmaceuticals solubility in supercritical carbon dioxide
The processing of pharmaceuticals by supercritical fluids requires the correct assessment and prediction of the solubility of solid compounds in a...
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Precise heteroatom do** determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
Develo** effective strategies to improve the hydrophilicity or aqueous solubility of hydrophobic molecular scaffolds is meaningful for both...
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Enhanced Solubility Through Particle Size Control, Modification of Crystal Behavior, and Crystalline Form Changes in Solid Dispersion of Nifedipine
The purpose of this study was to investigate the selectivity of polymers and the suitability of spray drying to enhance nifedipine solubility....
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Investigation of the solubility and thermodynamics of salicylic acid in 2-propanol and ethylene glycol/propylene glycol binary solvent mixtures at (293.15 to 313.15) K
This study aimed to measure both the solubility and thermodynamics of salicylic acid in binary solvent mixtures of (2-propanol + ethylene glycol) and...
