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Modern Natural Product Synthesis Overcoming Difficulties
In this book, key experts in the field of total synthesis of natural products in Japan describe the details of their synthesis routes including...
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Novel Plant Natural Product Skeletons Discoveries from 1999-2021
This book provides an overview of the new plant natural product skeletons discovered from 1999 to 2021. It categorizes these natural products by...
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New Tide of Natural Product Chemistry
This book highlights recent research and advances in natural product chemistry written by promising young researchers in this field who have played a...
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Cp2TiCl in Natural Product Synthesis
The synthesis of complex natural products constitutes one of the most exigent tests to prove the usefulness of a new reagent or catalyst. During...
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Strategic application of C–H oxidation in natural product total synthesis
The oxidation of unactivated C–H bonds has emerged as an effective tactic in natural product synthesis and has altered how chemists approach the...
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Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate
Enediyne natural products are renowned for their potent cytotoxicities but the biosynthesis of their defining 1,5-diyne-3-ene core moiety remains...
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Diene, Enyne, and Diyne Metathesis in Natural Product Synthesis
With the commercial availability of well-defined ruthenium metathesis catalysts which combine high stability and broad functional group...
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Natural product anticipation through synthesis
Natural product synthesis remains one of the most vibrant and intellectually rewarding areas of chemistry, although the justifications for pursuing...
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Soluble individual metal atoms and ultrasmall clusters catalyze key synthetic steps of a natural product synthesis
Metal individual atoms and few-atom clusters show extraordinary catalytic properties for a variety of organic reactions, however, their...
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Synthetic Biology-Based Natural Product Discovery
Natural products are historically one of the most important pharmaceutical sources for drug development. In the post-genomic era, next generation...
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Polydatin-based natural product as an activatable molecular sensor toward viscosity detection in liquid
Effective and non-invasive inspection method toward viscosity is expected to ease the burden of continued increased health problems worldwide....
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Natural Product Experiments in Drug Discovery
This detailed volume explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical...
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Synthetic Approach Toward Structural Elucidation of Marine Natural Product Symbiodinolide
Structural determination of natural products is a significant research topic in natural product chemistry. The combination of spectroscopic analysis...
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Post-translational backbone-acyl shift yields natural product-like peptides bearing hydroxyhydrocarbon units
Hydroxyhydrocarbon (Hhc) moieties in the backbone of peptidic natural products can exert a substantial influence on the bioactivities of the...
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From UK-2A to florylpicoxamid: Active learning to identify a mimic of a macrocyclic natural product
Scaffold replacement as part of an optimization process that requires maintenance of potency, desirable biodistribution, metabolic stability, and...
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AI-based prediction of protein–ligand binding affinity and discovery of potential natural product inhibitors against ERK2
Determination of protein–ligand binding affinity (PLA) is a key technological tool in hit discovery and lead optimization, which is critical to the...
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Modern Photocatalytic Strategies in Natural Product Synthesis
Modern photocatalysis has proven its generality for the development and functionalization of native functionalities. To date, the field has found...
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Strategies for Total and Diversity-Oriented Synthesis of Natural Product(-Like) Macrocycles
Numerous biologically active macrocycles, including antibiotic, antifungal, and antitumor compounds, have been isolated from natural sources. In...
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Discovery of Natural Product Analogues with Altered Activities by a High-Throughput Strategy
To exploit natural products as a source of biologically active compounds, accelerating the discovery of analogues that exhibit more potent and...