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Chemical synthesis as a discovery platform in immunosuppression and determination of mode of action
Over the past century, the use of organ transplantation to replace malfunctioning tissue has leapt from an impossibility to being a routine...
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Mode of Action of Biogenic Silver, Zinc, Copper, Titanium and Cobalt Nanoparticles Against Antibiotics Resistant Pathogens
The rapid surge in antibiotic resistance to pathogens has emerged as a grave threat to public health, globally. This multiple drug resistance (MDR)...
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Garvicin Q: characterization of biosynthesis and mode of action
Bacteriocins are ribosomally synthesized antimicrobial peptides, that either kill target bacteria or inhibit their growth. Bacteriocins are used in...
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Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action
Amphipathic α-helical peptides (AHPs) have shown potential as a therapeutic approach against multi-drug-resistant bacterial infections due to their...
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Antagonistic activity and mode of action of trypacidin from marine-derived Aspergillus fumigatus against Vibrio parahaemolyticus
This study aimed to investigate the antagonistic activity and mode of action of trypacidin from marine-derived Aspergillus fumigatus against Vibrio...
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Multi-mode Sliding Mode Control of Four-Cable Parallel Robot Based on Wind Disturbance Observation
Aiming at the problem of accurate trajectory tracking of four-cable parallel robot under wind disturbance in the process of material handling in...
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Isolation and characterization of flavonoids from roots of Rauvolfia serpentina and evaluation of their hypotensive potential through angiotensin-converting enzyme (ACE) inhibition mode of action
The purpose of this research was to characterize and identify novel bioactive flavonoids in Rauvolfia serpentina roots as natural, safe, and...
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Dual Mode of Action of Talaromyces purpureogenus CFRM02 Pigment to Ameliorate Alcohol Induced Liver Toxicity in Rats
Talaromyces purpureogenus CFRM02 pigment exhibited antioxidant activity by scavenging free radicals. The alcohol feeding leads to free radical...
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Anti-HSV nucleoside and non-nucleoside analogues: spectroscopic characterisation of naphthyl and coumarinyl amides and their mode and mechanism of antiviral action
Nucleoside analogues acyclovir, valaciclovir, and famciclovir are the preferred drugs against human Herpes Simplex Viruses (HSVs). However, the...
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Mechanism of Therapeutic Action of Rhodium Complexes
Rhodium complexesRhodium complexes have displayed a broad range of therapeutic activities including anticancer, antibacterial, antifungal, antiviral...
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Synergistic antimicrobial effect and mode of action of palmarosa oil-loaded nanoemulsion and citric acid against Pectobacterium carotovorum
The synergistic antimicrobial activity of palmarosa oil ( Cymbopogon martini , PO)-loaded nanoemulsion (PO-NE) and citric acid (CA) against Pectobacterium,...
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Influence of LED Power Mode on Resistance to Gamma Rays
Abstract—The effect of active and passive power supply modes on the resistance of light-emitting diodes (LEDs) fabricated on the basis of a...
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Molecular jackhammers eradicate cancer cells by vibronic-driven action
Through the actuation of vibronic modes in cell-membrane-associated aminocyanines, using near-infrared light, a distinct type of molecular mechanical...
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The specifics of the antioxidant action mechanism of cyclopentane anneled tetrahydroquinolines
The kinetics and mechanism of the antioxidant action of 4-(3-chlorophenyl)-3a,4,5,9b-tetrahydro-3 H -cyclopenta[ c ]quinoline (5),...
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Molecular Mechanism of Action of GPR91 Agonists and Antagonists: Insights from Molecular Dynamics Simulation
G protein-coupled receptor 91 (GPR91) has garnered widespread attention as a prospective therapeutic target for metabolic diseases. However, no...
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Kinetics of Paracetamol Degradation in Aqueous Solution by the Action of Dielectric Barrier Discharge in Oxygen
AbstractThe kinetics of decomposition of paracetamol in its aqueous solution by the action of atmospheric-pressure dielectric barrier discharge (DBD)...
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Preparation of Polymer-Based Amino Acid Stationary Phase and Its Application for Mixed-Mode Chromatography
Polymer microspheres have received attention because of their excellent properties. In this work, a polymer matrix zwitterionic amino acid stationary...
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Novel zone elution mode in coiled tube field-flow fractionation for online separation and characterization of environmental submicron particles
Coiled tube field-flow fractionation (CTFFF) is currently applied to environmental and material studies. In the present work, a novel zone elution...
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On a New Mode of Catalytic Sulfite Oxidation in the Presence of Mn(II) and Excess Metal Ions
AbstractData on the kinetics of sulfite oxidation catalyzed by manganese(II) ions in the presence of excess metal ions have been discussed....
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Tetrahydroquinolines as inhibitors of radical chain oxidation of organic compounds: kinetics and mechanism of action
The effectiveness and mechanism of the antioxidant action of a number of biologically active polysubstituted tetrahydroquinolines in a model reaction...
