Search
Search Results
-
Heterocycles from Cycloaddition Reactions
The synthesis of heterocyclic compounds via catalytic cycloaddition reactions of metallocarbenes is robust, atom-economic, and often allows access to...
-
Heterocycles from Cyanobacteria
Targets of cyanobacterial heterocyclic cytotoxins classify into tubulin, actin, and the sodium channel. In addition, cyanobacteria produce...
-
Heterocycles from Onium Ylides
Ylide intermediates are important in a variety of rearrangement reactions. In this chapter, we discuss recent advances in how ylide intermediates,...
-
Heterocycles from Donor and Donor/Donor Carbenes
This chapter reviews the recent advances of donor and donor–donor carbenes for the synthesis of heterocycles. Since new sources of donor-type...
-
Heterocycles from Cascade Reactions via Carbene gem-Difunctionalization
Cascade reactions via metal carbene gem-difunctionalization, which are initiated by metal-catalyzed carbene formation, followed by nucleophilic...
-
Heterocycles from Sulfur Ylides
Sulfur ylides (SY) are a special class of zwitterionic compounds that possess the ability to mediate different transformations. Represented by...
-
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations
Controlled microwave heating has found many important applications in the synthesis of heterocycles. Almost all kinds of heterocycles have been...
-
Photo-Induced Carbene Transformations to Heterocycles
Heterocycles are biologically relevant molecules with broad applications in pharmaceutical and agrochemical research. Among the countless approaches...
-
Cobalt(III) hydride HAT mediated enantioselective intramolecular hydroamination access to chiral pyrrolidines
Enantioenriched pyrrolidines and derivatives are ubiquitous substructures in compounds of importance to medicinal and biological chemistry. Herein,...
-
Heterocycles from Cyclopropanation of Five-Membered Heteroarenes
The cyclopropantion of five-membered heteroarenes provides a facile entry to a broad variety of heterocycles, capitalizing on the high reactivity of...
-
Planar Chiral Ferrocenes: A Concise Introduction
Due to its intrinsic beauty and unique properties, bis(η5-cyclopentadienyl)iron or ferrocene continues to attract the attention of chemists even...
-
Synthesis of Chiral 1,4,2-Oxazaphosphorinanes Bearing Pyridyl Substituents
AbstractA series of 1,4,2-oxazaphosphorinanes was synthesized by the three-component reaction of chiral pyridylcontaining imines with trialkyl...
-
Carbene-catalyzed enantioselective seleno-Michael addition as access to antimicrobial active Se-containing heterocycles
Organoseleniums exhibit a diverse set of biological activities that are pivotal for drug discovery and are widely explored in synthetic chemistry and...
-
Alkynes as Carbene Precursors for the Synthesis of Heterocycles
Catalytic metal carbene-involved transformations are considered as one of the most important aspects in homogeneous transition metal catalysis. The...
-
New Synthetic Approaches to Benzo-Fused Spiro Heterocycles
AbstractThe review describes syntheses of new benzo-fused spiro heterocycles by reactions of isatins, oxindoles, and indenoquinoxalines with...
-
Condensed azole-based organophosphorus heterocycles
This review summarizes for the first time the literature data on the methods of constructing with covalent bonds condensed systems based on...
-
Sparteine as a Chiral Ligand for Asymmetric Catalysis
While the use of stoichiometric amounts of sparteine and related ligands in various asymmetric reactions often lead to highly enantioselective...
-
Synthesis of chiral piperidines from pyridinium salts via rhodium-catalysed transfer hydrogenation
Chiral piperidines are widespread in natural products and drug molecules. However, effective methods for their synthesis from simple starting...
-
The Intramolecular Povarov Tool in the Construction of Fused Nitrogen-Containing Heterocycles
Nitrogen heterocycles are part of the structure of natural products and agents with important biological activity, such as antiviral, antibiotic, and...
-
Cyanomethyl pyridinium and isoquinolinium salts: a versatile chemical reagent for the synthesis of annulated heterocycles
Over the years, numerous advancements have been in synthesizing various heterocyclic compounds using pyridinium ylides. Imidazo pyridine derivatives...
