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Computational insight of repurpose drug for treatment of COVID-19: a CDFT approach
The COVID-19 is recognized as one of the deadly disease in the history of human life. It is caused by the severe acute respiratory syndrome...
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Current Strategies to Combat COVID-19
The outbreak of the novel coronavirus disease (COVID-19) has created global crisis. It originated from Wuhan, China, and has outspread globally. The...
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On topological indices of Molnupiravir and its QSPR modelling with some other antiviral drugs to treat COVID-19 patients
The global pandemic caused by the novel virus SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus 2), also known as COVID-19, is now a serious...
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Bioactive components of different nasal spray solutions may defeat SARS-Cov2: repurposing and in silico studies
The recent outbreak “Coronavirus Disease 2019 (COVID-19)” is caused by fast-spreading and highly contagious severe acute respiratory syndrome...
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Determination of Umifenovir and Its Metabolites by High-Performance Liquid Chromatography with Combined Mass Spectrometric Detection
AbstractAn approach to the highly sensitive and selective determination of the bromine-containing antiviral drug umifenovir (Arbidol) and its...
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A review on recent theoretical approaches made in the discovery of potential Covid-19 therapeutics
SARS CoV-2 virus (COVID-19) emerged as a highly infectious human pathogen in late 2019. Started in China but rapidly started spreading all over the...
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Coumarins as Emerging Anti-Viral Compounds from Natural Origins: Ethnopharmacology, Chemistry, Mechanism of Action, Clinical and Preclinical Studies, and Future Perspectives
From the natural origin, more than 1300 coumarins have already been recognized. Coumarins are natural products and secondary metabolites in plants,...
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Coumarins as Emerging Antiviral Compounds from Natural Origins: Ethnopharmacology, Chemistry, Mechanism of Action, Clinical, Preclinical Studies, and Future Perspectives
From the natural origin, more than 1300 coumarins have already been recognized. Coumarins are natural products and secondary metabolites in plants,...
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Computational screening for investigating the synergistic regulatory potential of drugs and phytochemicals in combination with 2-deoxy-D-glucose against SARS-CoV-2
COVID-19 disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was declared a global pandemic by the World Health...
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Drugs for COVID-19 Treatment: A New Challenge
COVID-19 infection is a new disease and our knowledge is limited; day in and day out more and more interesting yet diverse observations are reported...
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RETRACTED ARTICLE: Discovery of (E)-N-(4-cyanobenzylidene)-6-fluoro-3-hydroxypyrazine-2-carboxamide (cyanorona-20): the first potent and specific anti-COVID-19 drug
AbstractSpecific inhibition of the viral RNA-dependent RNA polymerase (RdRp) of the newly-emerged severe acute respiratory syndrome coronavirus 2...
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The Repurposed ACE2 Inhibitors: SARS-CoV-2 Entry Blockers of Covid-19
The highly infectious disease COVID-19 is induced by SARS-coronavirus 2 (SARS-CoV-2), which has spread rapidly around the globe and was announced as...
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Drug Delivery Options for Treatment of Ebola Infection
In West Africa, the Ebola virus disease (EVD) outbreak between 2013 and 2016 is considered as one of the deadliest re-emerging viruses, which began...
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COVID-19: Molecular Pathogenesis and Prospective Therapeutic Interventions
COVID-19 is a catastrophe taking a massive toll on humanity across the world. It is a highly transmissible airborne infection. The pathogen...
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Analytical validation of a microwave-assisted ICP-MS method for the quantification of elemental impurities in doxycycline hyclate tablets
Elemental impurities are generated in pharmaceuticals at various stages of the manufacturing process and storage. The presence of elemental...
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A Convenient One-Pot Synthesis of Bis(indolyl)methane Derivatives and Evaluation of Their Nematicidal Activity against the Root Knot Nematode Meloidogyne incognita
AbstractSeven arylbis(indolyl)methanes were synthesized by electrophilic substitution reaction of aromatic aldehydes on indole using glacial acetic...
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A computational study of potential therapeutics for COVID-19 invoking conceptual density functional theory
The pandemic, COVID-19, has caused social and economic disruption at a larger pace all over the world. Identification of an effective drug for the...
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Extraction of Eugenol from Essential Oils by In Situ Formation of Deep Eutectic Solvents: A Green Recyclable Process
Eugenol is extensively utilized in chemical industry. In actual production, it is mainly separated from clove essential oils (EOs) through acid–base...
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Biological activity and synthesis of 5,6-dihydroxyindole-2-carboxylic acid – biosynthetic precursor of melanins (microreview)
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Determination of Azithromycin Used in the Treatment Protocol of COVID-19 Based on Spectrophotometric Reactions: A Review
Azithromycin (AZM) drug is one of the most popular antibiotics and was extensively prescribed to treat patients during the first wave of COVID-19...
