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Transdermal Drug Delivery Systems
The transdermal drug delivery systems, also known as TDDS, are the most effective alternative to the oral and parenteral routes to deliver...
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A Percutaneous Delivery System for a Nicotinamide Transdermal Therapeutic System
Abstract —A percutaneous delivery system for nicotinamide is developed and its functional properties are studied in vitro. Four compositions of the...
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Dendrimer-conjugated isotretinoin for controlled transdermal drug delivery
BackgroundIn the present study, we aimed to develop a novel isotretinoin delivery model for treating skin diseases, revealing its potential...
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Deep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs
BackgroundTransdermal delivery of sparingly soluble drugs is challenging due to their low solubility and poor permeability. Deep eutectic solvent...
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Investigation of Paracetamol Entrapped Nanoporous Silica Nanoparticles in Transdermal Drug Delivery System
An effort was made to administer paracetamol drug through transdermal patch, as no such formulation of this drug has been developed yet. The primary...
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Tailoring and Evaluation of Berberine Loaded Transethosomal Gel for Effective Transdermal Delivery: Optimization, Characterization, and in vitro Evaluation
Berberine is an isoquinolone alkaloid present in a wide variety of plants. Other than Type 2 diabetes and hypertension it is also found to have an...
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Liposomes modified with borneol-containing surfactants for transdermal delivery of hydrophilic substrates
New surfactants based on borneol (BA- n ) with various alkyl tail lengths ( n = 10, 12) were synthesized and studied as permeation enhancers for...
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Cellulose nanofiber-reinforced dissolving microneedles for transdermal delivery of a water-soluble compound
Cellulose nanofibers (CNFs) were included in dissolving microneedle (MN) arrays to increase needle stiffness and control the dissolving rate and...
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Ethosomes for Dermal and Transdermal Drug Delivery Systems
The process by which a therapeutic agent or drug is administered to the body for achieving desired effects is known as drug delivery. In the...
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Development of Piperine-Loaded Soft Binary Ethosomal Gel to Improve Transdermal Delivery: Box-Bhekhen Design Optimization, Ex-Vivo Permeation, and Antimicrobial Evaluation
Natural bioactive compounds have been used to treat various diseases but have some limitations like poor solubility as well as low bioavailability....
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Development and evaluation of reservoir transdermal polymeric patches for controlled delivery of diclofenac sodium
The purpose of the study was to prepare a reservoir-controlled transdermal drug delivery patches containing a diclofenac sodium (DS) as a model drug...
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Electrical Stimuli-Responsive Gelatin/Shellac Gel Blends for Use as Controllable Transdermal Delivery Patches
To improve and increase drug permeation efficiency and hydrogel stability, a gelatin/shellac (Gel/SL) hydrogel was prepared for use in transdermal...
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Drug Delivery Systems for Cartilage
A dense network of extracellular matrix and lack of vascularization pose a major challenge in the delivery of therapeutics in the cartilage. Recent...
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Electrically controlled transdermal ibuprofen delivery consisting of pectin-bacterial cellulose/polypyrrole hydrogel composites
Pectin/bacteria cellulose (BC) hydrogel composites with various BC contents have been fabricated for the purpose of electrically controlled...
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Advances in microneedles for transdermal diagnostics and sensing applications
Microneedles, the miniaturized needles, which can pierce the skin with minimal invasiveness open up new possibilities for constructing personalized...
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Development of film forming gel for the delivery of 5-flurouracil: in-vitro/ex-vivo evaluation
The transdermal route is an important delivery system for the delivery of both systemic and local effects. The effectiveness of therapy is based on...
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Polymer Vesicles with Upper Critical Solution Temperature for Near-infrared Light-triggered Transdermal Delivery of Metformin in Diabetic Rats
Near-infrared light (NIR) triggered transdermal drug delivery systems are of great interest due to their on-demand drug release, which enable to...
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Current Status of Microneedle Array Technology for Therapeutic Delivery: From Bench to Clinic
In recent years, microneedle (MN) patches have emerged as an alternative technology for transdermal delivery of various drugs, therapeutics proteins,...
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Advanced Drug Delivery Methods and Applications
This book provides an overview of various drug delivery systems at the cellular level including biological, chemical methods, and most importantly...
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Lipase-Catalyzed Epigallocatechin Gallate-Based Polymer for Long-Term Transdermal Administration
Epigallocatechin gallate (EGCG) is an antioxidant agent with many advantageous pharmaceutical properties such as anti-cancer, anti-virus, and...
