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Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine
Perilla frutescens is an annual herbaceous plant widely cultivated for oil production in China, Japan, and Korea. In this study, we investigated the...
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Wuliangye Baijiu but not ethanol reduces cardiovascular disease risks in a zebrafish thrombosis model
Understanding how Baijiu facilitates blood circulation and prevents blood stasis is crucial for revealing the mechanism of Baijiu for cardiovascular...
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Antithrombic effects of Piper retrofractum in a rat model of acute thrombosis: modulation of endothelial adhesion molecules and inflammatory factors
Piper retrofractum (PR) is a tropical plant used as a spice in Southeast Asia. This study investigated the antithrombotic effect of PR in rats with...
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Analysis of Thrombosis Formation and Growth Using Microfluidic Chips and Multiphase Computational Fluid Dynamics
Thrombosis is a vascular disease associated with severe risks such as heart attack and stroke. Extensive research has been conducted worldwide to...
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Downregulation of miR-125a-5p Promotes Endothelial Progenitor Cell Migration and Angiogenesis and Alleviates Deep Vein Thrombosis in Mice Via Upregulation of MCL-1
Endothelial progenitor cells (EPCs) contribute to recanalization of deep vein thrombosis (DVT). MicroRNAs (miRNAs) play regulatory roles in functions...
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SARS-CoV-2 Vaccines: Types, Working Principle, and Its Impact on Thrombosis and Gastrointestinal Disorders
In the current scenario of the coronavirus pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), considerable efforts have...
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Study on the Effect and Mechanism of miR-185 on Lower Extremity Deep Venous Thrombosis
Lower extremity deep venous thrombosis (LEDVT) is a venous reflux disorder caused by abnormal coagulation of blood. LEDVT can obstruct the lumen and...
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A heparin–rosuvastatin-loaded P(LLA-CL) nanofiber-covered stent inhibits inflammatory smooth-muscle cell viability to reduce in-stent stenosis and thrombosis
BackgroundAn endovascular covered-stent has unique advantages in treating complex intracranial aneurysms; however, in-stent stenosis and late...
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RETRACTED ARTICLE: Protective Capability of Cu(II) Complex Delivered by Ultrasonic Intervention on Deep Venous Thrombosis
By using a mixed-ligand approach, a new Cu(II)-based coordination polymer, whose chemical formula is [Cu 2 (DPFE)(oba) 2 ] n ( 1 ), was synthesized through...
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Biomimetic platelet-camouflaged drug-loaded polypyrrole for the precise targeted antithrombotic therapy
Lower extremity deep venous thrombosis (LEDVT) affects patient’s quality of life for a long time, and even causes pulmonary embolism, which threatens...
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Extracellular vesicles in venous thromboembolism and pulmonary hypertension
Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension (PH) is a serious condition characterized by pulmonary vascular...
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Prosthetic Vascular Grafts: Past, Present, and Future
Prosthetic vascular grafts (PVGs) have made a striking progress during the past more than 100 years. Dacron and ePTFE are the two main PVGs. Even now... -
Development of a chemiluminescence assay for tissue plasminogen activator inhibitor complex and its applicability to gastric cancer
BackgroundVenous thromboembolism (VTE), is a noteworthy complication in individuals with gastric cancer, but the current diagnosis and treatment...
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Assessment of Induction and Destruction of Thrombi
Microbial infection may increase the risk of thrombosis. Infection associated thrombosis is importantly mediated by inflammation. Inflammation... -
Advances in D-dimer testing: progress in harmonization of clinical assays and innovative detection methods
The D-dimer is a sensitive indicator of coagulation and fibrinolysis activation, especially valuable as a biomarker of intravascular thrombosis....
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6-Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc-Labeling of Small Biomolecules
99mTc-labeled small biomolecules are a class of receptor-based, target specific radiopharmaceuticals for the detection of various diseases, such as... -
Tea polyphenol-derived nanomedicine for targeted photothermal thrombolysis and inflammation suppression
Thrombotic diseases impose a significant global health burden, and conventional drug-based thrombolytic therapies are encumbered by the risk of...
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Dual-mode nanoprobe strategy integrating ultrasound and near-infrared light for targeted and synergistic arterial thrombolysis
Efficient thrombolysis in time is crucial for prognostic improvement of patients with acute arterial thromboembolic disease, while limitations and...
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Nanomaterial-Mediated Theranostics for Vascular Diseases
Vascular diseases are widely known to be the leading cause of death and disabilities across the world. Although the conventional treatment methods...