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Bergenin alleviates Diabetic Retinopathy in STZ-induced rats
Diabetic retinopathy (DR) is the key cause of blindness and visual impairment in diabetes patients around the world. The high levels of oxidative...
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Blended extract of oat, sorghum, adzuki bean, finger millet, and proso millet improved hyperglycemia and insulin resistance in the streptozotocin–nicotinamide-induced diabetic rats
Grains contain bioactive components that potentially have protective effects on chronic diseases such as diabetes. The anti-diabetic effects of...
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Luteolin Mitigates Diabetic Dyslipidemia in Rats by Modulating ACAT-2, PPARα, SREBP-2 Proteins, and Oxidative Stress
Diabetic dyslipidemia is a crucial link between type-2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular diseases (ASCVD). Natural...
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The Hypoglycemic and Hypolipidemic Effects of Polyphenol-Rich Strawberry Juice on Diabetic Rats
Obesity and diabetes are some of the most important modern health problems requiring simple preventative or palliative measures using dietary means....
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Protective and health-promoting impact of Washingtonia filifera oil on the kidney of STZ-induced diabetic mice
Diabetes kidney damage (DKD) is a chronic inflammatory disease of the kidney induced with continuous hyperglycemia as the most prevalent consequence...
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Inonotus obliquus polysaccharide ameliorates serum profiling in STZ-induced diabetic mice model
BackgroundDiabetes mellitus is a systemic disease mainly caused by the disorder of metabolism, which has become huge threat to human health....
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Double emulsion-based mayonnaise encapsulated with bitter gourd extract exhibits improvement in vivo anti-diabetic action in STZ induced rats
Bitter gourd contains charantin (steroidal saponins), insulin-like peptides, and alkaloids, which contribute to its hypoglycemic ability. The study...
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Antihyperglycemic and hypolipidemic effect of yellow-fleshed cassava/wheat flour composite bread in high fat/streptozotocin induced diabetic rats
Yellow -fleshed cassava flour (CF) and wheat flour (WF) composite bread was prepared in various proportions of 100:0 (100% CF), 50:50 (50% CF:50%...
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Hepatoprotective Effect of Morin Hydrate in Type 2 Diabetic Wistar Rats Exposed to Diesel Exhaust Particles
Studies have shown that exposure to air pollutants such as diesel exhaust particles (DEP) exacerbate diabetes complications. Morin hydrate (MH), a...
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Protective effect of lactoferrin administration against brain tissue damage in diabetic rats
Bovine lactoferrin (bLf), a glycoprotein with iron, Several of Lf's functions intervene through various cell receptors. Its antibacterial,...
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Antidiabetic activity of Cichorium intybus L water extract against streptozotocin-induced diabetic rats
Diabetic mellitus is a chronic, incurable metabolism disorder caused by the lack of secretion of insulin by the pancreas. Currently, several plants...
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Alpha-lipoic acid modulates the diabetes mellitus-mediated neuropathic pain via inhibition of the TRPV1 channel, apoptosis, and oxidative stress in rats
Diabetes mellitus (DM) is a chronic syndrome involving neuropathic pain. Increased oxidative stress in DM is assumed to increase free reactive oxygen...
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Nigericin Abrogates Maternal and Embryonic Oxidative Stress in the Streptozotocin-Induced Diabetic Pregnant Rats
Hyperglycemic exposure in diabetic pregnancy can lead to many developmental changes, such as delayed development, fetal malformations, and...
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Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats
BackgroundDiabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and the main cause of non-traumatic amputation,...
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Diazoxide improves muscle function in association with improved dyslipidemia and decreased muscle oxidative stress in streptozotocin-induced diabetic rats
Aim/Introduction: Diabetes Mellitus is a chronic degenerative disease, and its main biochemical characteristic is hyperglycemia due to impaired...
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Chemical profile and beneficial effect of standardized extract of Stevia rebaudiana Bertoni leaves on metabolic syndrome in high fat diet streptozotocin-induced diabetic rats
Stevia ( Stevia rebaudiana Bertoni) is a natural zero calorie sweetener with significant economic and medicinal values due to its high contents of...
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Protective Effects of the Bilobalide on Retinal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
Diabetic retinopathy (DR) is a diabetes mellitus (DM) complication that causes visual acuity impairment and loss of sight in the working population,...
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Engineering Camelina sativa Seeds as a Green Bioreactor for the Production of Affordable Human Pro-insulin that Demonstrates Anti-diabetic Efficacy in Rats
The current production of recombinant insulin via fermenter-based platforms ( Escherichia coli and yeast) could not fulfill its fast-growing...
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Modulatory effects of photobiomodulation in the anterior cingulate cortex of diabetic rats
Anterior Cingulate Cortex (ACC) has a crucial contribution to higher order pain processing. Photobiomodulation (PBM) has being used as integrative...
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Influence of Tangeretin on the Exponential Regression of Inflammation and Oxidative Stress in Streptozotocin-Induced Diabetic Nephropathy
Diabetes is an amalgamation of metabolic disorders marked by hyperglycemia. Over time diabetes brings up several other complications with it like...
