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Synthesis and antinociceptive activity of nitriles, esters, and amides of 2-amino-1-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-4-oxo-5-(2-oxo-2-arylethylidene)-4,5-dihydro-1H-pyrrole-3-carboxylic acids
Synthesis of nitriles, esters, amides of the substituted 2-amino-1-(4,5,6,7-tetra-hydrobenzo[ b ]thiophen-2-yl)-4-oxo-5-(2-oxo-2-arylethylidene)-4,5-dihydro-1...
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Feasible study on poly(Pyrrole-co-Pyrrole-3-Carboxylic Acid)-modified electrode for detection of 17β-Estradiol
Preparation and characterizations of poly(pyrrole- co -pyrrole-3-carboxylic acid) (PPYPA) film on the surface of screen printed carbon electrode (SPE)...
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Computational investigation of 4,5-diphenyl-1H-pyrrole-3-carboxylic acid derivatives as B-cell lymphoma-extra large (Bcl-xL) inhibitors by using 3D-QSAR, molecular docking, and molecular dynamics simulations
B-cell lymphoma-extra large (Bcl-xL) can inhibit apoptosis via heterodimerization with pro-apoptotic Bcl-2 family proteins, and is over-expressed in...
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Nanoarchitectonics of a new rGO/poly(p-aminobenzoic acid) (pPABA)-based molecularly imprinted polymer electrode for detecting ascorbic acid, uric acid and glucose
Develo** electrochemical sensors for ascorbic acid, uric acid and glucose detection provides advantages of rapid, precise and economical monitoring...
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Coumarin-3-carboxylic acid: C3/C4-functionalizations and cyclization reactions
AbstractDue to the presence of a carboxyl group, coumarin-3-carboxylic acid can easily participate in C3-, and C4-functionalization, as well as...
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Experimental and theoretical characterization of chelidonic acid structure
Chelidonic acid (4-oxo-4H-pyran-2,6-dicarboxylic acid) is present in plants of Papaveraceae family, especially in Chelidonium majus . Due to its...
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A Citric Acid-Assisted Method for Constructing Multi-dimensional Acid-Resistant Fe/N/C Catalysts for Oxygen Reduction Reactions
Iron–nitrogen co-doped carbon (Fe/N/C) catalysts derived from zinc-based zeolite imidazole frameworks (ZIF-8) have been ideal alternatives to...
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5-Arylpyrrolidine-2-carboxylic Acid Derivatives as Precursors in the Synthesis of Sulphonyl-substituted Pyrroles
Abstractcis -5-Arylpyrrolidine-2-carboxylates, obtained by 1,3-dipolar cycloaddition reactions from glycine aryl aldimines and vinyl sulfones,...
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Ascorbic acid as a multifunctional hydrogen bonding catalyst for Paal–Knorr synthesis of N-substituted mono- and bis-pyrroles: experimental and theoretical aspects
Ascorbic acid could be applied as a recyclable organocatalyst for the preparation of pyrroles via Paal–Knorr condensation of hexane-2,5-dione with...
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Electrochemical synthesis of polypyrrole composite with modified gold nanoparticles for electrochemical detection of ascorbic acid, dopamine and acetaminophen in different pharmaceutical samples
This study introduces an electrochemical sensor designed for the determination of ascorbic acid (AA), dopamine (DA), and acetaminophen (AC). The...
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Synthesis of New 1,3,4-Oxadiazole and 1,2,3-Triazole Derivatives of Thieno[3,2-b]pyrrolecarboxylic Acid
AbstractNew 1,3,4-oxadiazole and 1,2,3-triazole derivatives of 4-benzyl-4 H -thieno[3,2- b ]pyrrole-5-carbohydrazide and methyl...
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Identification of Bile Acid-Derived Chemical Chaperone(s) Targeting E46K-Mutated Alpha-Synuclein Protein to Treat Parkinson’s Disease: Molecular Modelling, Docking, ADME, and Simulation Studies
Aggregated α-synuclein (α-syn) present inside small cytoplasmic inclusions in the substantia nigra region marks the major pathological hallmark of...
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ACID SODIUM SALT OF 1H-PYRAZOLE-3,4,5- TRICARBOXYLIC ACID: SYNTHESIS, CRYSTAL STRUCTURE AND FEATURES OF INTRAMOLECULAR BONDS
AbstractThe oxidation reaction of 3,3′,5,5′-tetramethyl-1H,1′H-4,4′-bipyrazole in the HNO 3 –Fe 3+ system unexpectedly resulted in the formation of...
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Syntheses and Crystal Structures of Three Pyrrole-2-Carboxylate with C3-Symmetry
AbstractThe reaction of three equivalents of 2-(trifluoroacetyl)pyrrole with triols [RC(CH 2 OH) 3 , R=H, CH 3 , CH 2 OH] produce triesters of...
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Nanostructured poly(thiophene acetic acid)/Au/poly(methylene blue) interface for electrochemical immunosensing of p53 protein
A poly(thiophene acetic acid)/Au/poly(methylene blue) nanostructured interface was electrochemically assembled step-by-step on screen-printed carbon...
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Novel Self-assembled Isonicotinic Acid Derivative and Zinc Porphyrin Dyads and Applications in Dye Sensitized Solar Cells
A new self-assemblies based on double-deck dyes ZnTPP-Wi (i = 1–3) were synthesized and applied in dye-sensitized solar cells (DSSCs). Anchoring...
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Recent progress on asymmetric multicomponent reactions via chiral phosphoric acid catalysis
Multicomponent reactions (MCRs) are very important to provide enantiomerically enriched compounds with high structural diversity and complexity....
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Photo-induced energy and electron transfer in carboxylic acid functionalized bis(4′-tert-butylbiphenyl-4-yl)aniline (BBA)-substituted A3B zinc porphyrins
Three bis(4′- tert -butylbiphenyl-4-yl)aniline (BBA)-substituted A 3 B zinc porphyrins containing BBA attached to the three meso-positions of the...
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Chromogenic Anion Sensors
Chromogenic sensors for anions generally consist of two parts: anion receptors and chromophores. In this review, six types of chromogenic anion...
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Pyrrole Natural Products with Antitumor Properties
This review examines the antitumor activity and synthetic strategies for pyrrole-containing natural products possessing the oxygenated...