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In silico identification of phytochemical inhibitors for multidrug-resistant tuberculosis based on novel pharmacophore generation and molecular dynamics simulation studies
BackgroundMultidrug-resistant tuberculosis (particularly resistant to pyrazinoic acid) is a life-threatening chronic pulmonary disease. Running a...
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Tuberculosis: Current Treatment Options and Future Scope
Tuberculosis (TB) is a communicable disease that mainly affects the lungs. TB is the major cause of ill health and the leading cause of death from a...
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Metal Nanoparticles in Tuberculosis
Tuberculosis (TB) is a bacterial illness that affects a number of human organs, predominantly the lungs but also the liver, spleen, and spine. It...
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Tuberculosis and Drug Delivery System: Clinical Trials in TB
Tuberculosis (TB) is a communicable disease caused by the bacterium Mycobacterium tuberculosis which is the second most lethal infectious disease...
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Global Health and Tuberculosis; Past, Present, and Future
As we study tuberculosis as one of the leading causes of death from a single infection, it is important to understand the origins and interaction of...
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Perspectives on Anti-Tuberculosis Drug Discovery
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis and is the second leading reason of death worldwide from infectious diseases...
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Disease Models in Tuberculosis Research
Animal models in general and TB animal models in particular have been utilized in a variety of ways to enhance diagnosis and foster preventative...
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Polymeric Nanoparticles in Tuberculosis
Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis (Mtb). TB causes the most human deaths than any other...
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In Silico Approach for Phytocompound-Based Drug Designing to Fight Efflux Pump-Mediated Multidrug-Resistant Mycobacterium tuberculosis
Tuberculosis (TB), caused by the bacteria Mycobacterium tuberculosis , is one of the principal causes of death in the world despite the existence of a...
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Alginate Nanoparticles: A Potential Drug Carrier in Tuberculosis Treatment
Among all infectious diseases that afflict humans, tuberculosis (TB) remains the deadliest. At present, epidemiologists estimate that one-third of...
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Niosomes in Tuberculosis
Tuberculosis is a significant public health issue prevailing globally. Despite the progress in science and technology, TB is still an ongoing...
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New Drugs in Synthesis Research for Tuberculosis
Mycobacterium tuberculosis is the bacteria which causes tuberculosis. It is a significant public health concern worldwide. An estimated ten million...
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Potential of Herbal Drugs for Treatment of Tuberculosis
Worldwide, TB is estimated as the 13th leading cause of death and the second leading infectious disease after COVID-19. In 2020, an estimated...
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Bacteriocin Postbiotics for Tuberculosis Drug Development
Bacteriocins are ribosomally generated peptides containing antibacterial action generated by various bacteria that have the potential of regulating...
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Dendrimers-Based Drug Delivery in Tuberculosis
Tuberculosis (TB) is a disease caused by a microorganism (Mycobacterium tuberculosis) which invades the lungs and initiates the disease. Currently,...
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Nanosuspensions in Treatment of Tuberculosis
Tuberculosis (TB) is one of the prime reason of death globally and is tough to treat by most antibiotics, together with tuberculosis (TB) multidrug...
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Solid Lipid Nanoparticles in Tuberculosis
Tuberculosis (TB) is a deadly disease spread by single infection agents. It creates a huge burden on the healthcare system for the development of...
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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics
Drug metabolism is generally associated with liver enzymes. However, in the case of Mycobacterium tuberculosis ( Mtb ), the causative agent of...
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Surface-Modified Drug Delivery Systems for Tuberculosis Intervention
Tuberculosis (TB) presents as the second most lethal infectious disease after HIV/AIDS and has presented difficulty in treatment over the years, due...
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