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Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices
The cell membrane is a critical barrier for cellular homeostasis, integral to signaling and intercellular communication, and vital for understanding...
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Marine Natural Products Targeting Tumor Microenvironment
Discovery of marine natural products targeting tumor microenvironment, as well as the chemical approach toward the compounds is highlighted in this...
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Exosomes target HBV-host interactions to remodel the hepatic immune microenvironment
Chronic hepatitis B poses a significant global burden, modulating immune cells, leading to chronic inflammation and long-term damage. Due to its...
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Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment
Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its diagnosis and treatment are still impeded by our limited...
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Identification of Prognostic Genes in Acute Myeloid Leukemia Microenvironment: A Bioinformatic and Experimental Analysis
Acute myeloid leukemia (AML) is a lethal hematologic malignancy with a variable prognosis that is highly dependent on the bone marrow...
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Intelligent nanovesicle for remodeling tumor microenvironment and circulating tumor chemoimmunotherapy amplification
Imperceptible examination and unideal treatment effect are still intractable difficulties for the clinical treatment of pancreatic ductal...
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Inflammatory microenvironment regulation and osteogenesis promotion by bone-targeting calcium and magnesium repletion nanoplatform for osteoporosis therapy
Osteoporosis is the most common bone metabolic disease that affects the health of middle-aged and elderly people, which is hallmarked by imbalanced...
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Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review
Liver fibrosis could be the last hope for treating liver cancer and remodeling of the hepatic microenvironment has emerged as a strategy to promote...
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Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification
Vascular calcification often occurs in patients with chronic renal failure (CRF), which significantly increases the incidence of cardiovascular...
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High-Throughput Microenvironment Microarray (MEMA) High-Resolution Imaging
The interaction between cells and their surrounding microenvironment has a crucial role in determining cell fate. In many pathological conditions,...
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Tumor microenvironment-responsive DNA-based nanomedicine triggers innate sensing for enhanced immunotherapy
Lack of proper innate sensing inside the tumor microenvironment could reduce both innate and adaptive immunity, which remains a critical cause of...
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Nanometre-resolved observation of electrochemical microenvironment formation at the nanoparticle–ligand interface
The dynamic response of surface ligands on nanoparticles (NPs) to external stimuli critically determines the functionality of NP–ligand systems. For...
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Single-cell RNA-seq analysis decodes the kidney microenvironment induced by polystyrene microplastics in mice receiving a high-fat diet
In recent years, the environmental health issue of microplastics has aroused an increasingly significant concern. Some studies suggested that...
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A xonotlite nanofiber bioactive 3D-printed hydrogel scaffold based on osteo-/angiogenesis and osteoimmune microenvironment remodeling accelerates vascularized bone regeneration
BackgroundCoordination between osteo-/angiogenesis and the osteoimmune microenvironment is essential for effective bone repair with biomaterials. As...
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Seminoma subtypes differ in the organization and functional state of the immune microenvironment
Seminoma is the most common type of testicular germ cell tumors (TGCTs) among 15–44 years old men. Seminoma treatments include orchiectomy,...
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Tumor Microenvironment Activated Multifunctional Nanoparticles for Precisely Controlled Tumor Photothermal and Photodynamic Therapy
Therapeutic failures are always accompanied by surgery, chemotherapy, and radiotherapy when metastasis or therapeutic resistance is present in...
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Tumor microenvironment responsive nano-herb and CRISPR delivery system for synergistic chemotherapy and immunotherapy
Chemoresistance remains a significant challenge for effective breast cancer treatment which leads to cancer recurrence. CRISPR-directed gene editing...
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A Review on Nanomaterial-based Strategies for Manipulating Tumor Microenvironment to Enhance Chemodynamic Therapy
Cancer is a leading cause of death worldwide, and a series of strategies has been reported for tumor-specific therapy. Currently, chemodynamic...
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Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome
The immune system is closely associated with the pathogenesis of polycystic ovary syndrome (PCOS). Macrophages are one of the important immune cell...
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GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation
Induced pluripotent stem cells (iPSCs) are useful tools for modeling diseases and develo** personalized medicine. We have been develo** cancer...
