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Solubility and thermodynamic study of mesalazine in propylene glycol + 2-propanol mixtures
In the current study, the solubility of mesalazine in the binary mixtures of propylene glycol (PG) + 2-propanol was determined using a shake flask...
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Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 K
Mesalazine (5-ASA) is a medication utilized to treat inflammatory bowel diseases involving ulcerative colitis and Crohn’s disease. Mesalazine has...
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Stabilization of the DMSO Solvate of 2-Chloro-5-nitrobenzoic acid (Mesalazine Impurity M) by Bifurcated Hydrogen Bonds: Crystallographic, Spectroscopic, Thermal and Computational Studies
The strategy for choosing the optimal solvent DMSO to produce the solvate of Mesalazine impurity M is demonstrated and the possibility of selective...
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Equilibrium Solubility of Acetaminophen in Ternary Mixtures as a Tool for Design of Concentrated Parenteral Medications
The main purpose of this research was to evaluate the mass/volume percentage (% m / v ) solubility of acetaminophen (ACP) in {ethanol (EtOH)...
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Physicochemical characterization and in vitro evaluation of mesalazine/β-cyclodextrin inclusion complex loaded into chitosan nanoparticles
In the present study, we have prepared highly soluble MSZ- β -Cyclodextrin ( β -CD). UV–Vis method was employed to approve the successful formation of...
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Enzyme Catalyzed Synthesis of Water Soluble Mesalazine Oligomers and Evaluation of their Efficiency in Polypropylene Stabilization
Abstract5-Aminosalicylic acid, also known as mesalazine, was oxidized via biocatalytic pathway using Horseradish Peroxidase as catalyst. The...
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Electrochemical Sensor Based on a Nanocomposite of Carbon Dots, Hexadecyltrimethylammonium Bromide and Chitosan for Mesalazine Determination
AbstractA glassy carbon electrode modified with a nanocomposite consisting of carbon dots, hexadecyltrimethyl ammonium bromide and chitosan showed...
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Surfactant (CTAB)-Modified Composite Electrodes for Electrochemical Determination of Drugs
Surfactants are a class of substances that are known to reduce surface tension at the carbon paste electrode (CPE) interface. We see an increase in...
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Interaction of sulfasalazine with outer surface of boron-nitride nanotube as a drug carrier in aqueous solution: insights from quantum mechanics and Monte Carlo simulation
The improvement of the solubility of sulfasalazine in physiological media was the major aim of this study. Accordingly, BNNT inspected as a notable...
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Alginate Based Matrix Tablet for Drug Delivery
The polymer-based matrix tablets are mostly used to manufacture orally prolonged released dosage forms due to the cost savings and relative ease of...
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Electrochemical Sensing and Biosensing-Based on Carbon Nanodots
Carbon quantum dots (CQDs) or simply carbon nanodots (CNDs) represent emerging materials in the form of nanocarbon, which have been advocated for...
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The Ageing Microbiome, Pharmaceutical Considerations, and Therapeutic Opportunities
Research in recent years has illuminated the importance of the microbiome for human wellbeing and healthy ageingHealthy ageing. Numerous age-related...
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Alginate–zein composite modified with metal organic framework for sulfasalazine delivery
Metal–organic frameworks (MOFs) have promising prospects as drug nanocarriers but are more limited in biomedical applications due to their poor...
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Ionically Gelled Pectinates in Drug Delivery
Pectins are hydrophilic linear anionic polysaccharide extracted from plant cell walls. These are inexpensive, biodegradable and biocompatible in...
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Phloretin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology
Phloretin is a dihydrochalcone found in various plant sources such as apples, strawberries, kumquat, pears, honeybush, and sweet tea. Numerous...
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Isabgol
Plantago ovata Forsck., is a herbaceous annual medicinal plant, usually known as commonly psyllium or Isabgol. It has been used traditionally used...
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Silicon Carbide and Its Germanium Dopant Nanocluster Derivatives as Sensors for Chloropicrin: Perception from Density Functional Theory and Monte-Carlo MD Simulation
Pivotal to this research is the computational investigation of the nanosensing resourcefulness of silicon carbide, Si 12 C 12 nanocage for the...
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Combination of polylactide with cellulose for biomedical applications: a recent overview
This review summarizes the use of cellulose and polylactide for medical applications with particular emphasis on modern dressings. Although classic...
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Biophysical and theoretical investigation of benzo[c]coumarin functionalized Schiff base with human serum albumin
The studies on molecular interactions of drug candidates with HSA have considerably contributed to the understanding of primary biological evaluation...
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Loading of 5-aminosalicylic in solid lipid microparticles (SLM)
5-Aminosalicylic acid (5-ASA), the active moiety of sulphasalazine, is the most commonly used drug for treating patients with inflammatory bowel...
