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The Role of Melanin in Fungal Disease
Many fungi produce melanins, which can play critical roles in virulence and pathogenicity. In fungal pathogenic species, melanin confers protection...
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Extraction, Purification, and Characterization of Microbial Melanin Pigments
Melanin pigments are dark black to brown coloured, hydrophobic, negatively charged, natural heterogeneous biopolymers. Melanin existence within a...
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Melanin Synthesis in Bacteria: Who, How and Why
There are different pathways leading to the synthesis of several kinds of melanin in Nature, most of which have been found in bacteria. In some of...
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Melanin in Auricularia auricula: biosynthesis, production, physicochemical characterization, biological functions, and applications
Auricularia auricular ( A. auricula ), a nutritious fungus and traditional medicinal resource, is known for melanin. This review aims to summarize the...
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In Silico Molecular Docking Approach of Melanin Against Melanoma Causing MITF Proteins and Anticancer, Oxidation–Reduction, Photoprotection, and Drug-Binding Affinity Properties of Extracted Melanin from Streptomyces sp. strain MR28
Melanin is a biopolymer reported for diverse biological actions to secure organisms over adverse environmental factors. In the last decade, melanin...
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Manipulating the antioxidative capacity of melanin-like nanoparticles by involving condensation polymerization
Melanin is ubiquitous in nature and plays important roles in physiological activities especially in kee** the oxidative balance. Both natural and...
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Multifunctional Peptide-Melanin Hybrid Nanodots with Robust Anti-Cutaneous Photoaging Activity
Skin aging is a systematic and complex process, mainly including intrinsic aging caused by time change and extrinsic aging caused by environmental...
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Fundamentals and Applications of Optically Active Melanin-Based Materials
Melanin is a group of ubiquitous biological pigments. It has excellent photonic properties such as broadband light absorption and high refractive...
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A New Human Uveal Melanoma Cell Line: Melanin Production and Molecular Markers for Targeted Therapy
AbstractA new human uveal melanoma (UM) cell line uMel1 was established by mechanical disintegration of a tumor fragment. uMel1 cells had a stellate...
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Production and characterization of melanin pigment from black fungus Curvularia soli AS21 ON076460 assisted gamma rays for promising medical uses
Owing to the growing need for natural materials in different fields, studying melanin production from biological sources is imperative. In the...
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Bioproduction and optimization of newly characterized melanin pigment from Streptomyces djakartensis NSS-3 with its anticancer, antimicrobial, and radioprotective properties
BackgroundMelanin is a natural pigment that is considered a promising biomaterial for numerous biotechnological applications across several...
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Structural disruption of melanin-like polymers with boosted UV protection
Manipulating the energy structure of materials represents an efficient way to regulate their light absorption behaviors. For example, constructing...
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Melanin-like nanoparticles: advances in surface modification and tumour photothermal therapy
Currently, tumor treatments are characterized by intelligence, diversity and personalization, but the therapeutic reagents used are often limited in...
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Efficient Production of Melanin by Aureobasidium Melanogenum Using a Simplified Medium and pH-Controlled Fermentation Strategy with the Cell Morphology Analysis
Natural melanin is a biopolymer with wide application prospects in medicine, food, cosmetics, environmental protection, agriculture, and so on....
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Improved natural melanin production by Aspergillus nidulans after optimization of factors involved in the pigment biosynthesis pathway
BackgroundMelanin is a natural pigment that can be applied in different fields such as medicine, environment, pharmaceutical, and nanotechnology....
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Protective effect of melanin nanoparticles created from squid ink against irradiation on human keratinocytes
Because the skin is the first organ to be impacted by radiation, keratinocytes (HaCaT cells) are frequently used as an in vitro model for testing...
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Melanin Treatment Effect of Vacuoles-Zinc Oxide Nanoparticles Combined with Ascorbic Acid
Currently, ascorbic acid (AA) is widely used as a skin whitening material, but, AA, an unstable hydrophilic molecule, cannot penetrate the skin...
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Impact of Lysosomal Fraction on Melanin Synthesis Inhibition in a Zebrafish Melanogenesis Phenotype Model
To develop whitening cosmetic materials, we conducted a study on lysosomes that decisively contribute to the decomposition of melanin during...
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Biosynthesis, Characterization, and Bioactivity of L-Alanyl-L-tyrosine in Promoting Melanin Synthesis
L-Alanyl-L-tyrosine (L-Ala-Tyr) is a dipeptide formed by the condensation of L-alanine methyl ester and L-tyrosine. After entering the body, it can...
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Chitosan–Melanin Polymer Complex: A Promising Ingredient in Emulsion Compositions
AbstractA new multifunctional biologically active ingredient—a polymer chitosan–melanin complex from Hermetia illucens black lion fly—has been...
