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Toxicity of energetic nanomaterials assessed on L929 fibroblasts
The widespread use of energetic materials (EMs) has increased human exposure to these substances, and the potential toxicity of nano-sized EMs...
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Dithiothreitol reduces oxidative stress and necrosis caused by ultraviolet A radiation in L929 fibroblasts
Ultraviolet A (UVA) radiation, present in sunlight, can induce cell redox imbalance leading to cellular damage and even cell death, compromising skin...
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Fagopyrin F fraction from Fagopyrum tataricum demonstrates photodynamic inactivation of skin infecting bacterium and squamous cell carcinoma (A431) cells
Photodynamic therapy (PDT) stands out as a noteworthy development as an alternative targeted treatment against skin ailments. While PDT has advanced...
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Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells
Cancer associated drug resistance is a major cause for cancer aggravation, particularly as conventional therapies have presented limited efficiency,...
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An Aligned Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Scaffold Fixed with Fibronectin to Enhance the Attachment and Growth of Human Endothelial Progenitor Cells
Repair and regeneration of vascular tissue is a crucial current research focus in the fields of biomedical engineering and regenerative medicine....
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Tri-layered Polycaprolactone/Taxol/Gelatin/5-FU Nanofibers Against MCF-7 Breast Cancer Cells
Nanofibers prepared by the electrospinning process are good candidates for the local delivery of anticancer drugs. In the present study,...
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Eco-Friendly Fabrication of Nanocurcumin/Nano Iron Oxide Composite: Enhanced In Vitro Anticancer Activity Against DLD-1 Cell Lines
Cancer has recently become one of the leading causes of mortality across the globe and has persisted as a severe health concern for the past several...
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A nucleolin-activated polyvalent aptamer nanoprobe for the detection of cancer cells
Sensitive detection of cancer cells plays a critical role in early cancer diagnosis. Nucleolin, overexpressed on the surface of cancer cells, is...
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Development of a Novel Sulfur Quantum Dots: Synthesis, 99mTc Radiolabeling, and Biodistribution
AbstractSulfur quantum dots (SQDs) as free heavy metal element quantum dots have promising applications in diagnosis and therapy; however, SQDs’ in...
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Thymol incorporated gellan gum/carboxymethyl cellulose/hyaluronic acid films for wound dressings applications
In the presented study, thymol-containing wound dressing films were prepared in the presence of polysaccharide gellan gum, carboxymethyl cellulose...
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Water-soluble N-heterocyclic carbene precursors bearing benzimidazole core: synthesis, characterization, in vitro antioxidant and anticancer studies
Benzimidazole is an important member of the nitrogen-containing heterocyclic ring system since it confers surprisingly good biological properties in...
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In vitro cytotoxicity and wound healing activities of quaternary blended carboxymethyl cellulose-hydroxypropyl methylcellulose composite film
A quaternary blended composite film (CHPCHO) of carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC) was prepared with polyvinyl...
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Enhancing the efficacy of nano-curcumin on cancer cells through mixture design optimization of three emulsifiers
Curcumin, a vital bioactive compound found naturally, has diverse biological applications. However, a major limitation of curcumin is its low...
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Vibropolyfection: coupling polymer-mediated gene delivery to mechanical stimulation to enhance transfection of adherent cells
BackgroundWith the success of recent non-viral gene delivery-based COVID-19 vaccines, nanovectors have gained some public acceptance and come to the...
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Characterization of chitin and description of its antimicrobial properties obtained from Cydalima perspectalis adults
Chitin is the most abundant biopolymer group after cellulose and forms the exoskeleton of arthropods, the largest animal group. The morphology of...
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Mitochondriotropic Derivative of Ethyl Ferulate, a Dietary Phenylpropanoid, Exhibits Enhanced Cytotoxicity in Cancer Cells via Mitochondrial Superoxide-Mediated Activation of JNK and AKT Signalling
Specific targeting of anti-cancer drugs to mitochondria is an emerging strategy to enhance cancer cell killing whilst simultaneously overcoming the...
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Fluorescence anisotropy cytosensing of folate receptor positive tumor cells using 3D polyurethane-GO-foams modified with folic acid: molecular dynamics and in vitro studies
Integrated polyurethane (PU)–based foams modified with PEGylated graphene oxide and folic acid (PU@GO-PEG-FA) were developed with the goal of...
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In vitro cytocompatibility evaluation of nanostarch reinforced polyaniline-polyvinyl alcohol conductive bionanocomposites for skin tissue engineering application
In this study, we aimed to fabricate nanostarch (NS) reinforced polyaniline/polyvinyl alcohol (PANI-PVA) bionanocomposite of polyaniline-polyvinyl...
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Isolation, purification and characterization of quercetin from Cucumis sativus peels; its antimicrobial, antioxidant and cytotoxicity evaluations
The peels of C.s ativus are produced in large quantities in food processing industries and as kitchen-waste, resulting into tremendous loss of...
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Response surface methodology optimization extraction of polysaccharide from Tricholoma lobayense and its biological activities
The extraction of polar polysaccharides from the sporocarp of Trichicholoma lobayense (TLP) was optimised using a response surface approach. The...