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Reliable assessment of carbon black nanomaterial of a variety of cell culture media for in vitro toxicity assays by asymmetrical flow field-flow fractionation
Carbon black nanomaterial (CB-NM), as an industrial product with a large number of applications, poses a high risk of exposure, and its impact on...
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In Vitro Methodologies for the Safety Assessment of Drugs
Since ages, drugs have been used in some form or the other for treatment of several diseases. Safety assessment of drug is an important step required...
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Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments
Tuberculosis (TB) is one of the main causes of death from a single pathological agent, Mycobacterium tuberculosis ( Mtb ). In addition, the emergence...
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Mechanistic study of silica nanoparticles on the size-dependent retinal toxicity in vitro and in vivo
BackgroundSilica nanoparticles (SiO 2 NPs) are extensively applied in the biomedical field. The increasing medical application of SiO 2 NPs has raised...
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Toxicity and Immune Response
Here, cytotoxicity andImmune response immunogenicImmunogenic activities of CPPs in vitro and in vivo are summarized, which are required to achieve...
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Generation and Characterization of In Vitro Transcribed mRNA
Here we describe the in vitro preparation of mRNA from DNA templates, including setting up the transcription reaction, mRNA cap**, and mRNA...
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Convergent Fabrication of Allicin Loaded Polymeric Nanoparticles for Treatment of In Vitro Squamous Carcinoma Cells and Systemic Toxicity
Squamous carcinoma (SCC) is one of the most common types of cancer in the world. The increasing rates of industrialization and the subsequent...
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Synthesis, Structural Analysis, Theoretical Calculations, In Silico Prediction of Antibacterial Efficacy, Toxicity Assessment, In Vitro Antioxidant Evaluation and Polymerization Activity of Cobalt(II) Coordination Complexes of Para-biphenylol
In this study, we report synthesis of novel cobalt(II) para-biphenyloxides (complexes 1 and 2 ) by reacting cobalt(II) chloride...
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Rubus ellipticus fruits extract-mediated cuprous oxide nanoparticles: in vitro antioxidant, antimicrobial, and toxicity study
The aim of the present study was to synthesize biologically active cuprous oxide nanoparticles (Cu 2 O-NPs) using green nanotechnology from aqueous...
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Nanomaterials on Living Organisms: Reduction of Toxicity Toward Sustainability
In nanomaterials research, reducing toxicity to living organisms and improving safety is a major concern. There is an urgent need for the development...
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Lecithin Derived Nano-Propyl Gallate as Non-Toxic Anti-Inflammatory Agent: Synthesis, In-Vitro and In-Vivo Investigations
The current study describes the preparation of nano-formulation of propyl gallate (NPG vesicles) comprised of soya bean extracted soya-lecithin. The...
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Effect and Responses of Lead Toxicity in Plants
Heavy metalHeavy metal toxicityToxicity is becomingLead toxicity a great concern to living organism due to exponential population growth and futile...
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In Vitro Models and Molecular Markers for Assessing Nano-Based Systems Inflammatory Potential
When nanotechnology proved to be a promising science with applications in several areas, there was a need for studies regarding the toxicity of...
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Zinc Oxide Nanoparticles in Biomedical Applications: Advances in Synthesis, Antimicrobial Properties, and Toxicity Considerations
Zinc oxide (ZnO) nanoparticles are promising nanotherapeutics used in several biomedical applications. Some of the unique features of ZnO...
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Determination of Toxicity Through Cytotoxicity Assays
The purpose of present protocol is to assess the toxigenic potential of selected/isolated probiotic organism using MTT assay. Various bacteria have...
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In Vitro Techniques for Safeguarding Medicinal Plants with Antiallergic Properties
Medicinal plants possessing antiallergic properties are extensively used in several medicine systems across different countries. However, it is...
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In silico molecular docking of cyclooxygenase (COX-2), ADME-toxicity and in vitro evaluation of antioxidant and anti-inflammatory activities of marine macro algae
The marine ecosystem harbors unique and diverse bioactive compounds that can offer a vast repertoire of molecules with therapeutic properties. In the...
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In Vitro Genotoxicity/Mutagenicity Testing of Food Packaging
To ensure the safe use of packaging materials and food contact materials, genotoxicity assessment is one of the requirements of regulatory agencies...
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Toxicity of energetic nanomaterials assessed on L929 fibroblasts
The widespread use of energetic materials (EMs) has increased human exposure to these substances, and the potential toxicity of nano-sized EMs...
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Assessment of Developmental Toxicity in Zebrafish Model
According to the international guidelines, the drug administered to a woman of childbearing potential must undergo developmental toxicity testing in...