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Transcriptomics of Host–Pathogen Interaction
Plants encounter several pathogens in their lifetime, and both host and pathogen show altered gene expression in response to their interaction. These...
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Host–microbiome orchestration of the sulfated metabolome
Recent studies have demonstrated that metabolites produced by commensal bacteria causally influence health and disease. The sulfated metabolome is...
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Gene expression and involvement of signaling pathways during host–pathogen interplay in Orientia tsutsugamushi infection
Scrub typhus is a neglected tropical disease that affects one-third of the world’s population. The disease is caused by Orientia tsutsugamushi (OT),...
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Anti-foam cell activity of metabolites of a bacterium isolated from yogurt
Existing literature documents the beneficial effects of probiotics against atherosclerosis, a major cause of human death. However, it suffers from a...
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Chemical-Biology and Metabolomics Studies in Phage-Host Interactions
For many years, several studies have explored the molecular mechanisms involved in the infection of bacteria by their specific phages to understand...
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A novel BLUF photoreceptor modulates the Xanthomonas citri subsp. citri–host plant interaction
Plant–pathogen interaction is influenced by multiple environmental factors, including temperature and light. Recent works have shown that light...
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Contracting the Host Range of Bacteriophage T7 Using a Continuous Evolution System
Bacteriophage T7 is an intracellular virus that recognizes its host via tail and tail fiber proteins known as receptor-binding proteins (RBPs). The...
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Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium
Host-associated bacteria are increasingly being recognized as underexplored sources of bioactive natural products with unprecedented chemical...
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Draft genome sequencing of halotolerant bacterium Salinicola sp. DM10 unravels plant growth-promoting potentials
In this study, strain DM10 was isolated from mangrove roots and characterized as a halotolerant plant growth-promoting bacterium. Strain DM10...
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Photo-ANA enables profiling of host–bacteria protein interactions during infection
Bacterial pathogens rapidly change and adapt their proteome to cope with the environment in host cells and secrete effector proteins to hijack host...
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Immobilization of a broad host range phage on the peroxidase-like Fe-MOF for colorimetric determination of multiple Salmonella enterica strains in food
A broad host range phage-based nanozyme (Fe-MOF@SalmpYZU47) was prepared for colorimetric detection of multiple Salmonella enterica strains. The...
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Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125
BackgroundA significant fraction of the human proteome is still inaccessible to in vitro studies since the recombinant production of several proteins...
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Advanced Organotypic In Vitro Model Systems for Host–Microbial Coculture
In vitro model systems have been advanced to recapitulate important physiological features of the target organ in vivo more closely than the...
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The future of recombinant host defense peptides
The antimicrobial resistance crisis calls for the discovery and production of new antimicrobials. Host defense peptides (HDPs) are small proteins...
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Chemical Synthesis and Immunological Functions of Bacterial Lipid A for Vaccine Adjuvant Development and Bacterial-Host Chemical Ecology Research
Lipopolysaccharide (LPS), an outer membrane component of gram-negative bacteria, is a representative immune activator, and its active principle is...
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Insights from the genome sequence of Bacillus tropicus EMB20, an efficient β-lactamase-producing bacterium
We report here the whole-genome sequence of β-lactamase-producing bacteria Bacillus tropicus EMB20. The genome sequence of Bacillus tropicus EMB20...
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An Overview of Mycoviral Curing Strategies Used in Evaluating Fungal Host Fitness
The number of novel mycoviruses is increasing at a high pace due to advancements in sequencing technologies. As a result, an uncountable number of...
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Metabolism of Dietary Substrates by Intestinal Bacteria and Consequences for the Host Intestine
Numerous substrates from alimentary origin are metabolized by the gut microbiota. Their luminal concentrations are the net result of production,...
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Covalent Reactive Peptides to Block Protein–Protein Interactions and Inhibit Microbe–Host Interaction
A key step in enteropathogenic Escherichia coli (EPEC) infection of intestinal cells involves a Tir-induced actin reorganization. Nck mediates this...
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Proteomic analysis of the host–pathogen interface in experimental cholera
The microbial cell surface is a site of critical microbe–host interactions that often control infection outcomes. Defining the set of host proteins...
