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Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over 76.0 million people worldwide in 2020, with a predicted...
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Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update
Despite the existence of numerous eye drops in the market, most of them are not sufficiently effective because of quick clearance and the barriers...
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Association of VEGF Gene Polymorphism (rs699947) with Glaucoma and In-Silico Study of Antiglaucoma Bioactive Compounds
Vascular endothelial growth factor (VEGF) is a useful expert in various maturation and other problems such as glaucoma. VEGF gene is located on the...
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MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study
PurposeTo assess the association between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and the incidence of open-angle...
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Towards preventing exfoliation glaucoma by targeting and removing fibrillar aggregates associated with exfoliation syndrome
Exfoliation syndrome presents as an accumulation of insoluble fibrillar aggregates that commonly correlates with age and causes ocular complications,...
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Homeostatic alterations related to total antioxidant capacity, elemental concentrations and isotopic compositions in aqueous humor of glaucoma patients
Glaucoma is a multifactorial eye disease, characterized by progressive optic neurodegeneration. Elevation of the intraocular pressure is the main...
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Recent Developments for the Treatment of Glaucoma
Glaucoma is one of the leading causes of irreversible blindness globally, with over 75.0 million people anticipated to be affected in 2020 with that...
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Recent insights into dietary ω-6 fatty acid health implications using a systematic review
The American Heart Association suggests that consuming ω-6 fatty acids (5–10% of total energy) can prevent cardiovascular disease by improving...
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Bioactive Components for Ocular Health
Vision impairment significantly affects the quality of life. It is related to several diseases such as age-related macular degeneration (AMD),...
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Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery scientists due to various anatomical and physiological barriers....
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Phytochemical content and enzyme inhibitory effect of Heptaptera triquetra (Vent.) Tutin fruit against acetylcholinesterase and carbonic anhydrase I and II isoenzymes
AbstractHeptaptera triquetra (Vent.) Tutin (Apiaceae) is a potent plant with multiple effects. A recent study aimed to evaluate the bioactive...
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A3 Adenosine Receptor Ligands: From Discovery to Clinical Trials
Numerous classes of selective agonists, antagonists, and allosteric modulators of the A3 adenosine receptor (AR) have been reported. The...
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Immune modulating nanoparticles for the treatment of ocular diseases
Ocular diseases are increasingly influencing people’s quality of life. Complicated inflammatory mechanisms involved in the pathogenic process of...
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Neovascular glaucoma regulation by arylsulfonyl indoline-benzamide (ASIB) through targeting NF-kB signalling pathway
The present study investigated the effect of arylsulfonyl indoline-benzamide (ASIB) on neovascular glaucoma in the mice model in vivo. In the mice...
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Nano-biosensors for Diagnosing Infectious and Lifestyle-Related Disease of Human: An Update
At present time, a variety of infectious and lifestyle diseases are becoming life-threatening day by day. Development in technology and immergence of...
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Green HPLC method with time programming for the determination of the co-formulated eye drops of tafluprost and timolol in their challengeable ratio
A new, simple and selective HPLC method was implemented for the simultaneous estimation of tafluprost (TFL) and timolol (TIM) in their new...
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Angiotensin converting enzyme inhibitors/cyclodextrin inclusion complexes: solution and solid-state characterizations and their thermal stability
Angiotensin converting enzyme (ACE) inhibitors have recently gained attention as a new class of drug in the therapeutic management of glaucoma....
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Polydopamine nanoparticles attenuate retina ganglion cell degeneration and restore visual function after optic nerve injury
BackgroundOxidative stress contributes to retina ganglion cells (RGCs) loss in variety of ocular diseases, including ocular trauma, ocular vein...
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Synthesis of 3,5-Disubstituted-1,2,4-oxadiazole Sulfonamides in the Superbasic t-BuONa/DMAA System
AbstractAn improved synthesis of 3,5-disubstituted-1,2,4-oxadiazoles with a sulfonamide fragment is proposed. Our previously developed synthesis of...
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Efficient and knowledge-based hierarchal virtual screening applied to identify potential inhibitors of cholinesterase enzyme
Cholinesterases (ChEs) are pivotal in the pathophysiology of various neuromuscular diseases, including Parkinson’s disease, Alzheimer’s disease,...
