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Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion injury via altering microglia polarization
Cerebral ischemia/reperfusion (CI/R) injury is a clinical conundrum during the treatment of ischemic stroke. Cell-derived exosomes (CDE) were proved...
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Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion
AbstractPlant-derived exosome-like nanoparticles (PDENs) have been paid great attention in the treatment of ulcerative colitis (UC). As a proof of...
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Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator
Along with the recognized therapeutic outcomes of regenerative medicine, extracellular vesicles and their exosome subsets have become an alternative...
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Exosome-like nanovesicles derived from Phellinus linteus inhibit Mical2 expression through cross-kingdom regulation and inhibit ultraviolet-induced skin aging
BackgroundPhellinus linteus (PL), which is a typical medicinal fungus, has been shown to have antitumor and anti-inflammatory activities. However,...
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Effect of Solanum lycopersicum and Citrus limon–Derived Exosome-Like Vesicles on Chondrogenic Differentiation of Adipose-Derived Stem Cells
Articular cartilage defect treatment is a very important problem because its therapeutic options are not successful enough. Due to the weak...
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Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis
BackgroundPlant-derived exosomes-like nanovesicles (PDENs) have been found to be advantageous in disease treatment and drug delivery, but research on...
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Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy
BackgroundUlcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by diffuse inflammation of the colonic mucosa and a relapsing...
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Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood–brain-barrier penetration and tumor microenvironment modulation
Inhibition of tumor growth and normalization of immune responses in the tumor microenvironment (TME) are critical issues for improving cancer...
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Therapeutic and Diagnostic Uses of Magnetic Nanoparticles in Cancer
Magnetic nanoparticle (MNP)-based technologies are now often used in biological systems for therapeutic or diagnostic applications. Recent...
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Magnetic Nanoparticles for Protein Separation and Purification
Proteins are essential for various functions such as brain activity and muscle contraction in humans. Even though food is a source of proteins, the...
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Natural lipid nanoparticles extracted from Morus nigra L. leaves for targeted treatment of hepatocellular carcinoma via the oral route
The clinical application of conventional medications for hepatocellular carcinoma treatment has been severely restricted by their adverse effects and...
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Modern Biomedical Applications of Magnetic Nanoparticles
As illustrated in Chap. 1 , the utilization of MNPs in biomedical applications is considered to have...
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Extraction, Optimization, Characterization, and Antioxidant Activities of Chinese Wild Rice Nanoparticles
Plant-derived extra-cellular vesicles are a new food resource, rich in functional factors. However, the extraction rate of nanoparticles is low....
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Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted therapy, but their simple biological functionalization is...
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Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023
BackgroundHerbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers....
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Cytokine Response to Nanoparticles Bearing Nucleic Acid Cargo
Non-viral gene delivery systems have proved to be promising for treatment of various cancers and other diseases. They are actively explored in...
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CPP Functionalized Nanoparticles
In this chapter, the delivery of biomoleculesLiposome such as oligonucleotidesOligonucleotide, proteins, peptides and others by connection of the...
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Enhanced synthesis of antibody-functionalized gold nanoparticles for multiplexed exosome detection via mass signal amplification in LDI-TOF MS
We present a novel method for sensitive exosomal protein detection using organic matrix-free laser desorption/ionization time-of-flight mass...
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Co-crosslinking strategy for dual functionalization of small magnetic nanoparticles with redox probes and biological probes
Surface functionalization strategy is becoming a crucial bridge from magnetic nanoparticles (MNPs) to their broad bio-application. To realize the...
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Cell-Derived Exosome-Based Materials for Biomedical Applications
Exosomes are tiny membrane-bound vesicles of various compositions produced in the endosomal compartment of eukaryotic cells. These are secreted as...