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The FADS1 genotypes modify the effect of linoleic acid-enriched diet on adipose tissue inflammation via pro-inflammatory eicosanoid metabolism
PurposeFatty acid desaturase ( FADS ) variants associate with fatty acid (FA) and adipose tissue (AT) metabolism and inflammation. Thus, the role of FADS1...
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Investigation of stationary phases performance for eicosanoids profiling in RP-HPLC
Eicosanoids — oxidative derivatives from arachidonic acid — represent biologically active lipid mediators in inflammatory processes. Different...
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Eicosanoids Signals in SARS-CoV-2 Infection: A Foe or Friend
SARS-CoV-2 mediated infection instigated a scary pandemic state since 2019. They created havoc comprising death, imbalanced social structures, and a...
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Begrenzung und Beendigung der Immunantwort: Einflüsse von Lebensmittelkomponenten auf die Herabregulation und Beendigung der immunologischen Abwehrreaktion
Immunreaktionen müssen räumlich und zeitlich begrenzt im Rahmen einer physiologischen Homöostase ablaufen. Spezifisch-funktionale...
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Simultaneous profiling and quantification of 25 eicosanoids in human serum by ultrahigh-performance liquid chromatography coupled to tandem mass spectrometry
The eicosanoid metabolic pathway is responsible for mediating the production of various inflammatory factors that are closely related to the...
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Tissue pretreatment for LC–MS/MS analysis of PUFA and eicosanoid distribution in mouse brain and liver
Polyunsaturated fatty acids (PUFAs) and eicosanoids are important mediators of inflammation. The functional role of eicosanoids in...
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Recent insights into dietary ω-6 fatty acid health implications using a systematic review
The American Heart Association suggests that consuming ω-6 fatty acids (5–10% of total energy) can prevent cardiovascular disease by improving...
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In silico molecular docking of cyclooxygenase (COX-2), ADME-toxicity and in vitro evaluation of antioxidant and anti-inflammatory activities of marine macro algae
The marine ecosystem harbors unique and diverse bioactive compounds that can offer a vast repertoire of molecules with therapeutic properties. In the...
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Chronic Microinflammation as “Friendly-Fire” in Aging and Disease
Major lifestyle-related chronic diseases, including cancer and Alzheimer’s disease, are the consequences of long-term micro-inflammation in any...
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Modeling Anorexia Nervosa
Although the pathophysiology underlying anorexia nervosa (AN) has not been fully elucidated, inflammation appears to be a critical component of its...
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Cuminum cyminum
It is a slender, glabrous annual, around 30 cm tall, and with a much branched angular or striated main stem. It is cultivated in most parts of India,...
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Plant-Derived Natural Products Targeting Multiple Pathways as Potential Therapeutics in the Treatment of Parkinson’s Disease
Parkinson’s disease (PD) is a chronic neurodegenerative disorder (ND) characterised by gradual degradation of dopaminergic neurons in the substantia...
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Immungenetik: Einflüsse von Lebensmittelkomponenten auf die Expression immunrelevanter Gene
Die Immunantwort ist in ihrer Basis eine hochregulierte Ausprägung relevanter Geninformationen, die innerhalb eines aus DNA und Histon-Proteinen...
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Role of Functional Foods in Human Health and Disease Prevention
The functional foods cover a variety of food components such as class of bioactive compounds and substances. The functional foods are present in both...
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Tandem Mass Spectrometry and Ion Mobility Reveals Structural Insight into Eicosanoid Product Ion Formation
Ion mobility measurements of product ions were used to characterize the collisional cross section (CCS) of various complex lipid [M-H] − ions using...
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Modeling Anorexia Nervosa
Although the pathophysiology underlying anorexia nervosa (AN) has not been fully elucidated, inflammation appears to be a critical component of its...
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P2X4 Receptors in Immunity and Inflammation
The P2X4 receptor is an ATP-gated cation channel that is widely expressed in cells of the immune system. It is able to form heterotrimers by...
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Methods for the Analysis of Arachidonic Acid-Derived Metabolites in Platelets
Arachidonic acid (AA) is the precursor of a series of bioactive lipids with relevant cell signaling and pathophysiological actions. Arachidonic acid...
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Nigella sativa
It is a small, erect annual herb, up to 50 cm tall. It is cultivated for its seeds, and cultivation is restricted to certain parts of northern India.
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Ernährung und Volkskrankheiten
Dieses Kapitel bietet einen ersten Überblick darüber, welche Rolle unsere Ernährung für unsere Gesundheit spielt. In den letzten 50 Jahren hat sich...