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Anti-cancer drug-mediated increase in mitochondrial mass limits the application of metabolic viability-based MTT assay in cytotoxicity screening
The high-throughput metabolic viability-based colorimetric MTT test is commonly employed to screen the cytotoxicity of different chemotherapeutic...
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Microfluidic 3D Cytotoxic Assay
Microfluidic-based cytotoxic assays provide high physiological relevance with the potential to replace conventional animal experiments and...
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In Vitro Cytotoxicity Testing of Food Packaging
Colorimetric assays with tetrazolium salts allow rapid evaluation of cytotoxicity endpoints. These assays are based on the ability of viable cells to...
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Composite Nanoarchitectonics of Magnetic Silicon Dioxide-Modified Chitosan for Doxorubicin Delivery and In Vitro Cytotoxicity Assay
Develo** drug delivery carriers for highly selective, controlled, and sustained release of the anti-cancer drugs is one of the crucial issues in...
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Determination of Toxicity Through Cytotoxicity Assays
The purpose of present protocol is to assess the toxigenic potential of selected/isolated probiotic organism using MTT assay. Various bacteria have...
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3D hanging spheroid plate for high-throughput CAR T cell cytotoxicity assay
BackgroundMost high-throughput screening (HTS) systems studying the cytotoxic effect of chimeric antigen receptor (CAR) T cells on tumor cells rely...
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Synthesis, characterization, and cytotoxicity assay of γ-Fe2O3 nanoparticles coated with quercetin-loaded polyelectrolyte multilayers
We evaluated the cytotoxicity effect of polyelectrolyte–quercetin (PMQ)-coated iron oxide nanoparticles (Fe 2 O 3 ) on human ovarian carcinoma cell line...
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Deep Learning-Based Automated Analysis of NK Cell Cytotoxicity in Single Cancer Cell Arrays
The cytotoxicity assay of immune cells based on live cell imaging offers comprehensive information at the single cell-level information, but the data...
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Flounder fish (Paralichthys sp.) collagen a new tissue regeneration: genotoxicity, cytotoxicity and physical–chemistry characterization
Collagen dressings have been widely used as effective treatments for chronic wounds acting as barrier, protecting the area from infections and...
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Organic and inorganic antimicrobials incorporated into acrylic resin: antimicrobial efficacy and cytotoxicity: a systematic review
This review aimed to investigate the literature systematically and answer the question “Does the processing method of organic and inorganic agents...
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Nano-Resveratrol Liposome: Physicochemical Stability, In Vitro Release, and Cytotoxicity
Nano-resveratrol liposome (RES-LIP) was prepared by the thin film rotary-evaporated method combined with ultrasonication and characterized by...
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MicroRNA-483-3p Inhibitor Ameliorates Sepsis-Induced Intestinal Injury by Attenuating Cell Apoptosis and Cytotoxicity Via Regulating HIPK2
Sepsis is a life-threatening syndrome that can result in multi-organ dysfunction. MicroRNA (miR)-483-3p was previously demonstrated to be upregulated...
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Effect of 2-hydroxyethylammonium carboxylate protic ionic liquids on the solubility and cytotoxicity of indomethacin
Recently, there is a particular interest to utilize protic ionic liquids (PILs) in drug solubility. This study is exploring the effect of three...
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In Vitro and In Silico Studies on 4-Nitroacetophenone Thiosemicarbazone Potential Cytotoxicity Against A549 Cell Lines
AbstractLung malignancy is a major worldwide issue that occurs due to the dysregulation of various growth factors. Lung cancer has no apparent signs...
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Characterization and in vitro cytotoxicity of piperine-loaded nanoemulsion in breast cancer cells
Piperine is an alkaloid of natural origin with potent anti-cancer activity. However, due to its physicochemical characteristics, piperine's...
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Study on antioxidant activity and cytotoxicity of Aronia melanocarpa leaf tea extracts
Aronia leaf tea, which is generally discarded after harvesting the fruit, was prepared using three different methods. Water extract from dried Aronia...
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Lacticaseibacillus casei K11 exerts immunomodulatory effects by enhancing natural killer cell cytotoxicity via the extracellular regulated-protein kinase pathway
PurposeProbiotics can serve as immunomodulators that regulate the activation of immune cells. This study aimed to screen potential probiotic strains...
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Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl imidazole) complexes [Pd(AMI)Cl 2 ](1), [Cu(AMI)L 1 ](2), and...
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3D printed scaffolds of biosilica and spongin from marine sponges: analysis of genotoxicity and cytotoxicity for bone tissue repair
Biosilica (BS) and spongin (SPG) from marine sponges are highlighted for their potential to promote bone regeneration. Moreover, 3D printing is...
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Tackling assay interference associated with small molecules
Biochemical and cell-based assays are essential to discovering and optimizing efficacious and safe drugs, agrochemicals and cosmetics. However, false...
