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Alternatives to Conventional Antibiotic Therapy: Potential Therapeutic Strategies of Combating Antimicrobial-Resistance and Biofilm-Related Infections
Antibiotics have been denoted as the orthodox therapeutic agents for fighting bacteria-related infections in clinical practices for decades....
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Antibacterial and antibiofilm potentials of vancomycin-loaded niosomal drug delivery system against methicillin-resistant Staphylococcus aureus (MRSA) infections
The threat of methicillin-resistant Staphylococcus aureus (MRSA) is increasing worldwide, making it significantly necessary to discover a novel way...
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Cytocompatibility and Synergy of EGCG and Cationic Peptides Against Bacteria Related to Endodontic Infections, in Planktonic and Biofilm Conditions
This study evaluated the cytocompatibility and antimicrobial/antibiofilm effects of epigallocatechin-3-gallate (EGCG) associated with peptide LL-37...
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Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections
Antibiotic overuse has resulted in the microevolution of drug-tolerant bacteria. Understandably it has become one of the most significant obstacles...
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Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections
Enterococcus faecalis ( E. faecalis ) biofilm-associated persistent endodontic infections (PEIs) are one of the most common tooth lesions, causing...
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Recent Developments in the Treatment of Bacterial Urinary Tract Infections
Urinary tract infections (UTIs) are one of the most common infectious diseases among humans and account for over one million hospitalizations and... -
An overview of opportunistic fungal infections associated with COVID-19
The COVID-19 survivors and long-term steroid administered patients exhibit a variety of fungal co-infections. The lives of COVID-19 patients and...
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Potential of Desert Medicinal Plants for Combating Resistant Biofilms in Urinary Tract Infections
Urinary tract infections (UTIs) are among the most prevalent bacterial infections worldwide, with 11% of the global population getting infected every...
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Cuminaldehyde and Tobramycin Forestall the Biofilm Threats of Staphylococcus aureus: A Combinatorial Strategy to Evade the Biofilm Challenges
Staphylococcus aureus , an opportunistic Gram-positive pathogen, is known for causing various infections in humans, primarily by forming biofilms. The...
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Microbial Biofilms and the Role of Biotechnology as a Solution
In food industries, due to improper cleaning or control practices, along with certain other factors, pathogenic microbes and contaminants such as... -
H2O2 self-supplying and GSH-depleting nanosystem for amplified NIR mediated-chemodynamic therapy of MRSA biofilm-associated infections
Reactive oxygen species (ROS) has emerged as potent therapeutic agents for biofilm-associated bacterial infections. Chemodynamic therapy (CDT),...
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Antibiofilm Activity of Postbiotics
Over the past few decades, biofilm-mediated diseases have become more prevalent and resistant to antibiotics, necessitating a new approach to... -
Phytofabrication of biocompatible zinc oxide nanoparticle using Gymnema sylvestre and its potent in vitro antibacterial, antibiofilm, and cytotoxicity against human breast cancer cells (MDA-MB-231)
The increasing incidence of breast cancer and bacterial biofilm in medical devices significantly heightens global mortality and morbidity,...
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Bacterial cellulose-based scaffold: synthesis and surface modification for sustained rifampicin release for topic skin infections treatment
The present work aims to produce bacterial cellulose (BC) using Komagataeibacter hansenii, which was isolated after selective conditions in...
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Potential Use of Biotechnological Tools to Eradicate Microbial Biofilms
Microbial biofilms are an aggregation of microbial cells interconnected by extracellular polymeric substances (EPS), which accelerate the growth of... -
Photodynamic and nitric oxide therapy-based synergistic antimicrobial nanoplatform: an advanced root canal irrigation system for endodontic bacterial infections
BackgroundThe main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the...
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Unveiling the persistent threat: recent insights into Listeria monocytogenes adaptation, biofilm formation, and pathogenicity in foodborne infections
Listeriosis is a severe disease caused by the foodborne pathogen Listeria monocytogenes , posing a significant risk to vulnerable populations such as...
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A novel antimicrobial peptide YS12 isolated from Bacillus velezensis CBSYS12 exerts anti-biofilm properties against drug-resistant bacteria
Nowadays, the abuse of antibiotics has led to the rise of multi-drug-resistant bacteria. Antimicrobial peptides (AMPs), with broad-spectrum...
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Biofilms on Food Contact Surfaces: Current Interventions and Emerging Technologies
The surfaces that come in contact with all food-related activities are referred to as Food Contact Surfaces (FCS). FCS is very important in all... -
Deciphering antifungal and antibiofilm mechanisms of isobavachalcone against Cryptococcus neoformans through RNA-seq and functional analyses
Cryptococcus neoformans has been designated as critical fungal pathogens by the World Health Organization, mainly due to limited treatment options...