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Melt Processing Virus-Like Particle-Based Vaccine Candidates into Biodegradable Polymer Implants
Melt processing is an emerging production method to efficiently encapsulate proteins into polymeric devices for sustained release. In the context of...
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Biodegradable and biocompatible subcutaneous implants consisted of pH-sensitive mebendazole-loaded/folic acid-targeted chitosan nanoparticles for murine triple-negative breast cancer treatment
BackgroundMebendazole (MBZ) is a well-known anti-parasite drug with significant anti-cancer properties. However, MBZ exhibits low solubility, limited...
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Biodegradable dexamethasone polymer capsule for long-term release
We have developed sustained Dex (dexamethasone) capsule implants for sustained local delivery for inflammatory disease treatment. Four different...
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Biodegradable iron-based foams prepared by the space holder technique using urea
Iron-based degradable biomaterials have attracted much attention as next-generation bone implants due to their excellent mechanical properties and...
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Modeling Degradation Behavior of Biodegradable Polymers for Medical Devices: A Comparative Review of Phenomenological and Stochastic Approaches
Biodegradable polymers have a high potential in making medical devices such as absorbable esophageal and vascular stents, bone, orthopedic screws and...
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A road map on synthetic strategies and applications of biodegradable polymers
Biodegradable polymers have emerged as fascinating materials due to their non-toxicity, environmentally benign nature and good mechanical strength....
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Biodegradable Biliary Stents. Materials and Methods for Evaluating Functional Properties. A Review
AbstractThe review is devoted to analyzing published information concerning biodegradable biliary stents, materials and manufacturing technology, and...
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Peritoneal Implants and Drug Delivery
Peritoneal cavity owing to its physiological and anatomical features offers perfused capillaries to facilitate permeation for systemic delivery,...
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Ionic liquid treated bacterial cellulose sheets as prospective biodegradable implant materials
The purpose of this research was to create bacterial cellulose (BC) membranes/sheets which can be degraded by the enzymes in body fluids on...
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Biocompatible Hydrogels Based on Biodegradable Polyesters and Their Copolymers
AbstractPoly(ethylene glycol)-based hydrogels have long proved to be promising materials for various biomedical technologies. This review considers...
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Electrochemical and electrophoretic coatings of medical implants by nanomaterials
The demand for medical implants has rapidly increased over the last decades. These artificial devices should possess various properties such as...
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Ecotoxicity Assessment of Biodegradable Plastics in Marine Environments
Marine biodegradable and bio-based plastics (BPs) are required to be assimilated by microorganisms in aquatic environments and ultimately decomposed...
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Potential of Biodegradable Synthetic Polymers for Use in Small-diameter Vascular Engineering
Bypass or replacement surgery is required in patients with chronic atherosclerotic artery occlusions. In the absence of an autogenous vein, synthetic...
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Microbial-Derived Biodegradable Polymers as Food Packaging Tool
Plastic application is one of the crucial concerns due to the global environmental impact, and shifting to biodegradable food packaging would be a...
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Tuning the release rate of rilpivirine from PLGA-based in situ forming implants
In situ forming implants (ISFI) based on poly(lactic- co -glycolic acid) (PLGA) are promising long-acting injectable depots for the treatment of human...
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Downstream Processing Strategies for Synthesis of Biodegradable Polymers
Biodegradable materials are used as an alternative for conventional plastics in consumer goods and medical applications. Since these materials have...
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Materials Based on Chitosan and Polylactide: From Biodegradable Plastics to Tissue Engineering Constructions
AbstractThe transition to green chemistry and biodegradable polymers is a logical stage in the development of modern chemical science and technology....
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Synthesis of Biodegradable Lactide-Based Polymers in the Presence of Metal-Free Organocatalyst
AbstractThe polymerization of L -lactide mediated by the organic catalyst 1,8-diazabicyclo[5.4.0]undec-7-ene is studied. It is shown that the...
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A novel polycaprolactone/rice husk ash/hydroxyapatite biopolymer composite for bone implant: physico-mechanical and biodegradable analysis
Locally derived silica and hydroxyapatite (HAp) were incorporated into polycaprolactone (PCL) polymer to produce a biocomposite material with the...
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The Impact of Temperature on the Formation, Release Mechanism, and Degradation of PLGA-based In-Situ Forming Implants
This study explores the impact of varying temperatures on the release behavior of Triptorelin Acetate (TA) from a PLGA-based in-situ forming implant...
