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Photoredox catalytic alkylarylation of alkynes with arylsulfonylacetate as bifunctional reagent
Difunctionalization of alkynes represents a powerful and straightforward approach to the synthesis of complex molecules. However, the radical...
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Photoinduced difunctionalization with bifunctional reagents containing N-heteroaryl moieties
Bifunctional reagents that serve as dual coupling partners with an activating species have emerged as valuable synthetic tools in organic chemistry....
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Bifunctional Tools to Study Adenosine Receptors
Target-based G protein-coupled receptors (GPCRs) drug discovery has historically focused on the development of ligands that either activate or...
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Asymmetric synthesis of sulfoximines, sulfonimidoyl fluorides and sulfonimidamides enabled by an enantiopure bifunctional S(VI) reagent
An increased interest to expand three-dimensional chemical space for the design of new materials and medicines has created a demand for isosteric...
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Conjugate electrospun photochromic adjustable magnetic bifunctional Janus-structure nanofibers array
Using conjugate electrospinning technology to prepare Janus-structure nanofiber array and endow it with multifunctional characteristics is a very...
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6-Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc-Labeling of Small Biomolecules
99mTc-labeled small biomolecules are a class of receptor-based, target specific radiopharmaceuticals for the detection of various diseases, such as...
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Bifunctional two-carbon reagent made from acetylene via 1,2-difunctionalization and its applications
There are very limited approaches to directly gluing two molecules for the production of internal alkenes using the vastly abundant acetylene via ...
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An Efficient Bifunctional Core–Shell MIL-101(Cr)@MOF-867 Composite to Catalyze Deacetalization–Knoevenagel Tandem Reaction
By growing one metal organic frameworks (MOFs) on different metal organic frameworks plays an important role in catalytic reaction, but its...
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Nanofluidic Technologies for Drug Screening and Drug Delivery
Recently, nanofluidics exploiting 10–1000 nm spaces has developed and suggested a potential of novel analytical methods for pharmaceutical studies...
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Fabrication of bifunctional multiwalled carbon nanotubes@palygorskite nanofiber nanocomposite for electrochemical determination of niclosamide
Herein, we reported a novel niclosamide (NA) electrochemical sensor based on the multifunctional nanocomposite of palygorskite (Pal) nanofibers and...
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A bifunctional bortezomib-loaded porous nano-hydroxyapatite/alginate scaffold for simultaneous tumor inhibition and bone regeneration
Treatments of osteolytic lesions due to malignant metastasis remain one of the major clinical challenges. The residual tumor cells after surgical...
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Bifunctional Silicon Quantum Dots for Antibacterial Application and Highly Sensitive Detection of Tetracycline
Silicon quantum dots (SiQDs) with high water-soluble and favorable photostability were prepared by a one-step hydrothermal method. The average...
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Drug Delivery Systems and Cardiovascular Disease
Clinically, with the treatment of cardiovascular disease in addition to surgery and interventional therapy, drug therapy is also a common means. With...
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Injectable Hydrogel for Drug Delivery
Injectable hydrogels are of gel technology in the laboratory that improves the need for gel kinetic control. They have a carrier property in three...
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Assembling Au8 clusters on surfaces of bifunctional nanoimmunomodulators for synergistically enhanced low dose radiotherapy of metastatic tumor
BackgroundRadiotherapy is one of the mainstays of cancer therapy and has been used for treating 65–75% of patients with solid tumors. However,...
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Role of non-covalent interactions in deciding the fate of product formation in bifunctional thiourea-assisted chiral organic reactions
The present work reports the theoretical study of the reaction between anthrones and maleimides organocatalyzed by bifunctional thiourea. It has been...
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Introduction to Musculoskeletal Tissues and Drug Delivery Systems
Musculoskeletal tissues provide support, structure, and motion to the human body. This chapter deals with different tissues that comprise the...
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Preparation and characterization of steroid and umbelliferone-based hetero-bifunctional poly(ε-caprolactone)s for potential drug delivery systems: antimicrobial and anticancer activities
The present study contains a comprehensive study of steroid and umbelliferone-based modified poly(ε-caprolactone)s as a potential carrier for the...
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Polysaccharide-Based Drug Delivery Systems
Due to the incredible diversity of polysaccharides and their natural origin, these systems are essential because they can offer compatibility and...
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Surface-Modified Drug Delivery Systems in Malaria
Due to the large number of individuals afflicted, the intricacy of the causative agent life cycle, the protist Plasmodium sp., and the severity of...