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A solid preparation of phytochemicals: improvement of the solubility and bioavailability of astragaloside IV based on β-cyclodextrin microencapsulation
Astragaloside IV/β-cyclodextrin inclusion complex (AsIV/β-CD IC) was successfully prepared by low-temperature sedimentation technology. Under the...
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Astragaloside IV in Hypoxic Pulmonary Hypertension: an In Vivo and In Vitro Experiments
The objective of study was to find the actions of astragaloside IV (ASIV) on PAH due to monocrotaline (MCT) in rats. Intraperitoneal injection of...
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Solid-phase extraction with the functionalization of calcium-sensing receptors onto magnetic microspheres as an affinity probe can capture ligands selectively from herbal extract
Magnetic solid phase extraction with the functionalization of protein onto micro- or nano-particles as a probe is favorable for the discovery of new...
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Homologous-magnetic dual-targeted metal-organic framework to improve the Anti-hepatocellular carcinoma efficacy of PD-1 inhibitor
The insufficient abundance and weak activity of tumour-infiltrating lymphocytes (TILs) are two important reasons for the poor efficacy of PD-1...
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Traditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late fibrosis
Idiopathic pulmonary fibrosis (IPF) is a highly debilitating and fatal chronic lung disease that is difficult to cure clinically. IPF is...
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Simultaneous quantification of two active compounds in raw and honey-processed Radix Astragali by high-performance thin-layer chromatography
Radix Astragali is a traditional Chinese medicine (TCM), which strengthens the efficacy in tonifying Qi after honey-processing. However, a...
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Bioactive Electrospun Gelatin Membranes for Skin Wound Dressings
This literature review explores the novel applications of gelatin nanofibers obtained by electrospinning. This review used extensive data and... -
Comprehensive online two-dimensional liquid chromatography coupled to hybrid linear ion trap Orbitrap mass spectrometry with optimized dilution and modulation for analysis of Huangqi Guizhi Wuwu decoction
Huangqi Guizhi Wuwu decoction (HGWD), as a classical formula, has been used for thousands of years in China. In this work, a comprehensive strategy...
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Chemical comparison of Astragali Radix by UHPLC/Q-TOF-MS with different growing patterns
Astragali Radix (AR) is commonly used as the herbal drug in the traditional Chinese medicine. In this study, cultivated AR (AR-C) and wild/semi-wild...
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Advance and Challenge of Component-Effect Relationship in the Discovery of Active Components from Chinese Medicines
Active ingredients discovery has always been a hot topic for the research of Chinese medicines (CMs). The component-effect relationship is one of the... -
Omics in Quality Research of Chinese Medicines
The quality of Chinese medicines (CMs) is the basis to guarantee the clinical safety, effectiveness, and controllability of medicinal materials. It... -
Alginate Based Carriers for Topical Drug Delivery
Topical drug delivery is a promising approach for drug susceptible to degradation on oral administration or drug undergoing first pass effect.... -
Applications of Pressurized Liquid Extraction in Quality Control of Traditional Chinese Medicines
For many bioactive chemicals contained in traditional Chinese medicines, pressurized liquid extraction has become a preferred green extraction... -
Application of Thin-Layer Chromatography in Quality Control of Chinese Medicines
Thin-layer chromatography is a conventional analytical method in quality control of traditional Chinese medicines. Many advantageous characteristics... -
Quantitative comparison of bile acid glucuronides sub-metabolome between intrahepatic cholestasis and healthy pregnant women
Because of the pathological indication and the physiological functions, bile acids (BAs) have occupied the research hotspot in recent decades....
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Nutraceuticals and phytotherapeutics for holistic management of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis” (ALS) is a progressive neuronal disorder that affects sensory neurons in the brain and spinal cord, causing loss of...
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Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023
BackgroundHerbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers....
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Calotropis procera: UHPLC-QTOF-MS/MS based profiling of bioactives, antioxidant and anti-diabetic potential of leaf extracts and an insight into molecular docking
This work aims to investigate antioxidant/antidiabetic activities of aqueous and aqueous ethanol (20–80% ethanol:water, v/v) extracts from Calotropis...