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Methods for the Analysis of Arachidonic Acid-Derived Metabolites in Platelets
Arachidonic acid (AA) is the precursor of a series of bioactive lipids with relevant cell signaling and pathophysiological actions. Arachidonic acid... -
Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase
Acetylcholinesterase (AChE, E.C. 3.1.1.7) termed as the true cholinesterase functions to end cholinergic transmission at synapses. Due to its diverse...
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Contributing to the management of viral infections through simple immunosensing of the arachidonic acid serum level
A trendsetting direct competitive-based biosensing tool has been developed and implemented for the determination of the polyunsaturated fatty acid...
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ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism
Enolase 1 (ENO1) is a glycolytic enzyme that plays essential roles in various pathological activities including cancer development. However, the...
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Blended-protein changes body weight gain and intestinal tissue morphology in rats by regulating arachidonic acid metabolism and secondary bile acid biosynthesis induced by gut microbiota
PurposeThe impact of dietary nutrients on body growth performance and the composition of gut microbes and metabolites is well-established. In this...
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Maternal diet supplementation with high-docosahexaenoic-acid canola oil, along with arachidonic acid, promotes immune system development in allergy-prone BALB/c mouse offspring at 3 weeks of age
PurposeTo study the effects of feeding docosahexaenoic acid (DHA, derived from novel canola oil), with same amount of arachidonic acid (ARA),...
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Development of a quantitative proteomics approach for cyclooxygenases and lipoxygenases in parallel to quantitative oxylipin analysis allowing the comprehensive investigation of the arachidonic acid cascade
Oxylipins derived from the cyclooxygenase (COX) and lipoxygenase (LOX) pathways of the arachidonic acid (ARA) cascade are essential for the...
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Biochemical and Biophysical Characterization of Tau and α-Linolenic Acid Vesicles In Vitro
Alzheimer’s disease (AD) is characterized by the abnormal accumulation of disordered protein, that is, extracellular senile plaques of amyloid-β (Aβ)... -
α-Linolenic Acid Induces Microglial Activation and Extracellular Tau Internalization
Neuroinflammation is the brain condition that occurs due to the hyper-activation of brain’s immune cells and microglia, over the stimulation of... -
Nutritional evaluation, amino acid, and fatty acid properties of boiled ackee arils
Ackee fruit ( Blighia sapida ) is a tropical plant widely cultivated for its delicious and nutritious arils. However, due to the presence of toxic...
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Gas Chromatography for Omega-3 (ω-3) Fatty Acid Profiles of Microalgae
There are various types of fatty acids, which are essential nutrients for humans and affect the balance of dietary structure, endocrine stability,... -
Molecular mechanism of arachidonic acid biosynthesis in Porphyridium purpureum promoted by nitrogen limitation
The red alga Porphyridium purpureum has been known to produce polyunsaturated fatty acids, especially arachidonic acid (ARA), under stressful...
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Fatty acid composition of adipose tissue at term indicates deficiency of arachidonic and docosahexaenoic acid and excessive linoleic acid supply in preterm infants
BackgroundArachidonic (ARA) and docosahexaenoic acid (DHA) are constitutive to membrane phospholipids, and essential for brain and overall...
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Recent insights into dietary ω-6 fatty acid health implications using a systematic review
The American Heart Association suggests that consuming ω-6 fatty acids (5–10% of total energy) can prevent cardiovascular disease by improving...
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Milk fat globule membrane plus milk fat increase docosahexaenoic acid availability in infant formulas
PurposeMilk fat globule membrane (MFGM) has components with emulsifier properties that could affect the provision of substrates to the brain. We...
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N-3 PUFA supplementation alleviates anxiety symptoms by manipulating erythrocyte fatty acid levels in depression
PurposeMajor depressive disorder (MDD) is frequently accompanied by the symptoms of clinical anxiety. Since our previous research has found that n-3...
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Dietary fatty acid intake in childhood and the risk of islet autoimmunity and type 1 diabetes: the DIPP birth cohort study
PurposeThe aim was to study the associations between dietary intake of fatty acids in childhood and the risk of islet autoimmunity and type 1...
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Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe
PurposeHuman milk (HM) composition is influenced by factors, like maternal diet and body stores, among other factors. For evaluating the influence of...
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Leveraging the use of ionic liquid capillary columns and GC×GC-MS for fatty acid profiling in human colostrum samples
Lipids in human colostrum provide the majority of energy intake and essential fatty acids for develo** infants. The fatty acid composition of human...