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ACE-Inhibitory Peptides Identified from Quinoa Bran Glutelin-2 Hydrolysates: In Silico Screening and Characterization, Inhibition Mechanisms of ACE, Coordination with Zinc Ions, and Stability
To obtain Angiotensin-I-Converting Enzyme (ACE) inhibition peptides with Zn-chelating capacity, quinoa bran glutelin-2 hydrolysates (QBGH) by...
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Characterization of fermented pomegranate juice: ACE inhibitory activity under in vitro digestion, antioxidant capacity, phenolics composition, chemical properties and sensory evaluation
Consuming pomegranate juice (PJ) is beneficial for hypertensive regulation because of the phenolic compounds in PJ and their inhibitory activity on...
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Interaction mechanisms of ACE inhibitory peptides: molecular docking and molecular dynamics simulation studies on five wheat gluten derived peptides
The angiotensin I-converting enzyme (ACE) inhibitory activity of five wheat gluten-derived peptides Ala-Pro-Ser-Tyr (APSY), Leu-Val-Ser (LVS),...
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Comprehensive Understanding of the Relationship between Bioactive Compounds of Black Tea and its Angiotensin Converting Enzyme (ACE) Inhibition and Antioxidant Activity
Long term regular intake of black tea (BT) can lower blood pressure, which is probably due to its antioxidant activity and angiotensin converting...
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Characterization of ACE inhibitory peptide from Cassia tora L. globulin fraction and its antihypertensive activity in SHR
Cassia tora L. seeds, known as “juemingzi” in China, have been one of the key traditional Chinese medicines for thousands of years. When stir-fried,...
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The identification of antioxidant and ACE-I peptides in different turkish ripened cheeses
The principal purpose of this study was to determine antioxidant and ACE-inhibitory (angiotensin converting enzyme) activities of 5 ripened Turkish...
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A novel Angiotensin-I-converting enzyme (ACE) inhibitory peptide IAF (Ile-Ala-Phe) from pumpkin seed proteins: in silico screening, inhibitory activity, and molecular mechanisms
Pumpkin seed proteins with desirable nutritional properties have attracted great interest as an innovative source of bioactive peptides with...
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Isolation and characterization of flavonoids from roots of Rauvolfia serpentina and evaluation of their hypotensive potential through angiotensin-converting enzyme (ACE) inhibition mode of action
The purpose of this research was to characterize and identify novel bioactive flavonoids in Rauvolfia serpentina roots as natural, safe, and...
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In silico elucidation for the identification of potential phytochemical against ACE-II inhibitors
ContextThe present study aims to investigate the therapeutic potential of phytocompounds derived from Annona reticulata leaves for the treatment of...
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Fibrinolytic and ACE Inhibitory Activity of Nattokinase Extracted from Bacillus subtilis VITMS 2: A Strain Isolated from Fermented Milk of Vigna unguiculata
The current research work aims at optimization, production, purification and evaluation of fibrinolytic extracellular protease from Bacillus subtilis ...
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Antioxidant and angiotensin-I-converting enzyme (ACE-I) inhibitory activities of protein hydrolysates derived from water buffalo (Bubalus bubalis) liver
In the current study, we attempted to use ginger as a novel and natural source of protease in comparison with other commercially available enzymes to...
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Isolation, identification and activity analysis of antioxidant peptides from rice wine lees
In this study, antioxidant peptides were prepared by enzymatic digestion of wine lees proteins, and their identification and activity assay was...
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Protolytic equilibria of ACE inhibitors in micellar solution of nonionic surfactant Brij 35
The acid–base equilibria of six ACE inhibitors (ACEIs), captopril, cilazapril, enalapril, lisinopril, quinapril, and ramipril, were investigated in...
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LC-Q-TOF/MS based identification and in silico verification of ACE-inhibitory peptides in Giresun (Turkey) hazelnut cakes
Hazelnut ( Corylus avellana L.) cakes represent are a rich source of proteins. In an effort to valorize industrially cold-pressed hazelnut cakes,...
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Identification and Molecular Docking Analysis of Angiotensin-Converting Enzyme Inhibitors from Finger Millet (Eleusine coracana)
Hypertension remains a significant global health concern, contributing significantly to cardiovascular diseases and mortality rates. The inhibition...
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Targeting COVID-19 pandemic: in silico evaluation of 2-hydroxy-1, 2-diphenylethanone N(4)-methyl-N(4)-phenylthiosemicarbazone as a potential inhibitor of SARS-CoV-2
The global spread of the COVID-19 pandemic caused by the etiological agent, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), triggered...
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ACE inhibitory effect of the protein hydrolysates prepared from commercially available nori product by pepsin–trypsin digestion
We studied angiotensin I converting enzyme (ACE) inhibitory effect of the protein hydrolysates prepared from commercially available nori products...
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Modification of Marine Bioactive Peptides: Strategy to Improve the Biological Activity, Stability, and Taste Properties
Marine bioactive peptides (MBPs) are widely applied in functional foods and medicine industries. Several studies indicate that MBP consumption may...
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Purification, characterization and molecular docking study of angiotensin-I converting enzyme (ACE) inhibitory peptide from shortfin scad (Decapterus macrosoma) protein hydrolysate
Hypertension is a threatening chronic disease, which become a global killer among the adult population. The mortality rate increasing day by day even...
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Physicochemical properties and angiotensin-I converting enzyme inhibitory activity of lipid-free ribbon fish (Lepturacanthus savala) protein hydrolysate
The study aims at removal of lipid from ribbon fish protein hydrolysate (FPH) to enhance the protein content and analyse its physicochemical and...
