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The Efficient Knoevenagel Condensation Promoted by Bifunctional Heterogenized Catalyst Based Chitosan-EDTA at Room Temperature
An efficient heterogeneous catalyst-based low molecular weight chitosan (LWC) modified with EDTA groups were prepared and applied as a bifunctional...
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Synthesis and Study of Antimicrobial Activity of Water-Soluble Ammonium Acylhydrazones Based on New 1,ω-Alkylenebis(isatins)
Alkylation of isatin with 1,ω-dihaloalkanes afforded bis(heterocycles) connected by an oligomethylene linker. The reaction of the resulting...
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An efficient three-component synthetic protocol for the synthesis of structurally diverse spiroannulated benzothiazolopyrimidines catalyzed by l-proline in aqueous media
An environmentally sustainable domino protocol has been presented to synthesize structurally diverse...
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Nano-wheat bran-OSO3H: synthesis, characterization and application as an effective and novel nanocatalyst for one-pot synthesis of spirooxindoles
A novel nano-wheat bran-OSO 3 H catalyst prepared from mesoporous wheat bran as a support treated with chlorosulfonic acid (ClSO 3 H) has been proposed...
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Electrosynthesis of nano-sized pyran and chromene derivatives by one-pot reaction between cyclic-1,3-diketons, malononitrile/ethyl cyanoacetate, and isatins
AbstractAn efficient and sustainable method was developed for the electrocatalytic synthesis of nano-sized 4 H -pyran derivatives via a green,...
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Application of thin-layer chromatography in the assessment of bioactivity properties of isatin derivatives
In the last 20 years, isatin and its derivatives stand out as promising precursors in the synthesis of new pharmacologically active compounds. Since...
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Green synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazoles] using Fe3O4@l-arginine as a robust and reusable catalyst
The synthesized Fe 3 O 4 @ l -arginine showed strong catalytic performance in the one-pot synthesis of spiropyranopyrazoles via the reactions of...
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Double-Decker 3a,6a-Diaza-1,4-diphosphapentalenes in Deoxygenation Reactions: Reductive Coupling of Dimethylformamide
AbstractThe reaction of double-decker ditriflates based on 2,3,5,6-tetramethyl-1 H ,4 H -3a,6a-diaza-1,4-diphosphapentalene, (MeMeDDP) 2 (OTf) 2 , and...
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Atropoenantioselective synthesis of heterobiaryl N-oxides via dynamic kinetic resolution
A highly efficient enantioselective construction of heterobiaryl N -oxides was developed. A series of axially chiral heterobiaryl N -oxides were...
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Synthesis of Triazolylisatins Glycoconjugates and Some Ammonium Hydrazones on Their Basis
AbstractThe click reaction of propargylisatins with some azido-sugars was used to synthesize new isatin derivatives, in which the carbohydrate...
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New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH−] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone
AbstractA new nano-size crown ether-based ionic liquid on the basis of dibenzo-18-crown-6 ([DB-18-C-6K + ][OH − ] nIL) has been synthesized via a simple...
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Synthesis of 2-[(Pyrrol-2-yl)sulfanyl]acetic Acids by Reaction of Pyrrolo[2,1-c][1,4]oxazinetriones with 2-Sulfanylacetic Acid
Abstract8-Aroyl-3,4-dihydro-1 H -pyrrolo[2,1- c ][1,4]oxazine-1,6,7-triones reacted with 2-sulfanylacetic acid to give...
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NNN pincer palladium(II) complexes with N-(2-(1H-pyrazol-1-yl)phenyl)-picolinamide ligands: synthesis, characterization, and application to heck coupling reaction
N -(2-(1H-pyrazol-1-yl)phenyl)-picolinamide ligands 3a–c and 5a–f have been easily prepared from commercially available 2-pyridinecarboxylic acid....
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Durable magnetite-chitosan core–shell nanoparticles as reusable green nanocatalyst for the benign one-pot three-component synthesis of spirooxindoles and spirochromenes at ambient temperature under both solvent-free and ultrasonic conditions in aqueous ethanol solution
In the present research, a novel, efficient, and green nanocatalyst has been afforded by coating Fe 3 O 4 nanoparticles with chitosan through simple and...
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One-pot four-component synthesis of N-aryl-1,8‐dioxo‐decahydroacridines, N-arylquinolines and spiro[indoline-3,4′-quinolines] catalyzed by a new ionic liquid immobilized on nonporous SiO2
In this research, a new heterogeneous catalyst formulated as SiO 2 -[bip]-NH 2 + HSO 4 − was obtained from the immobilization of...
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Synthesis and study of cytotoxic activity of novel 3,3-bis(indol-3-yl)-1,3-dihydroindol-2-ones
A series of 3,3-bis(indol-3-yl)-1,3-dihydroindol-2-ones containing substituents at different positions of the oxindole ring were synthesized to study...
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Facile synthesis of new pyrano[3,2-c]quinolones via the reaction of quinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile
Synthesis of heteroannulated pyrano[3,2- c ]quinolones was established starting from the reaction of 4-hydroxyquinolin-2-ones with...
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Efficient synthesis of spirooxindole derivatives by magnetic and recyclable CaFe2O4@MgAl-LDH
A promising chemotherapeutic agent is spirooxindole. Probable targets involve cancers of the lung, liver, breast, colon, stomach, and prostate....
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Preparation, Characterization, and Application Magnetic Fe3O4@SiO2@Bi2O3 Nanoparticles for the Synthesis of Diindolyloxindole Derivatives
AbstractIn this study, synthesis of diindolyl oxindole derivatives has been developed by the coupling of indole compounds, isatin compounds,...
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Incorporation of 5-Nitroisatin for Tailored Hydroxyapatite Nanorods and its Effect on Cervical Cancer Cells: A Nanoarchitectonics Approach
AbstractHydroxyapatite (HAP) have been widely used as bone implants for its biocompatibility, and bioactivity. Other approaches like scaffold...
