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Evidence of population expansion and insecticide resistance mechanism in invasive fall armyworm (Spodoptera frugiperda)
BackgroundThe invasive and calamitous polyphagous pest Spodoptera frugiperda or commonly known as fall armyworm (FAW) poses serious menace to the...
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The antioxidant mechanism of exopolysaccharides’ synthesis from Agaricus bitorquis (Quél.) Sacc. Chaidam under the influence of Lycium ruthenicum Murr. anthocyanin extract
Agaricus bitorguis (Quél.) Sacc. Chaidam is a rare wild edible macro-fungus that grows underground at high altitudes. In this study, the mechanism of...
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Some Benzotriazole and Benzimidazole Derivatives as Antifungal Agents for Candida Species: A Molecular Docking Study
BackgroundThe efficacy of azole drugs has been reduced due to the emergence of drug resistant fungal pathogens. Despite this, heterocyclic compounds...
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Dissecting the conformational complexity and mechanism of a bacterial heme transporter
Iron-bound cyclic tetrapyrroles (hemes) are redox-active cofactors in bioenergetic enzymes. However, the mechanisms of heme transport and insertion...
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Assessment of anti-oxidant activity and quantification of epigallocatechin in Acacia suma heartwood by HPTLC-DPPH fingerprinting method
Research on natural anti-oxidant agents increased due to their wide range of applications on various diseases. HPTLC-DPPH is the novel technique...
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Biosynthesis and biotechnological production of the anti-obesity agent celastrol
Obesity is a major health risk still lacking effective pharmacological treatment. A potent anti-obesity agent, celastrol, has been identified in the...
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RuO2/rGO heterostructures as mimic peroxidases for colorimetric detection of glucose
The successful synthesis of ruthenium oxide/reduced graphene oxide (RuO 2 /rGO) heterostructures by one-pot hydrothermal method using graphene oxides...
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Metabolic engineering of Rhodotorula toruloides for resveratrol production
BackgroundResveratrol is a plant-derived phenylpropanoid with diverse biological activities and pharmacological applications. Plant-based extraction...
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LCMS Based Untargeted Metabolic Profiling Revealed a Strong Association of Nanoselenium Treated Sesame (Sesamum indicum) Seed Bioactive Compounds as Novel Potential Disease Targets- A Nano-bioinformatics Approach
The convergence of nanotechnology with bioinformatics and the study of plant secondary metabolites hold remarkable potential for transformative...
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Genetic identification of the sticktight flea Echidnophaga gallinacea (Westwood) infesting chickens in the Al-Baha region, Saudi Arabia
Stick-tight fleas, Echidnophaga gallinacea (Westwood), are major ectoparasites of domesticated chickens and can cause serious diseases and even death...
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Tacrolimus Induces Apoptosis in Leukemia Jurkat Cells through Inactivation of the Reactive Oxygen Species-dependent Phosphoinositide-3-Kinase/Akt Signaling Pathway
Tacrolimus, also named FK506, widely used as an immunosuppressant, is a kind of macrolide produced by Streptomyces tsukubaensis . Although tacrolimus...
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A novel mass spectrometry method for the absolute quantification of several cytochrome P450 and uridine 5′-diphospho-glucuronosyltransferase enzymes in the human liver
Cytochrome P450 (CYP450) and 5′-diphosphate glucuronosyltransferases (UGT) are the two major families of drug-metabolizing enzymes in the human liver...
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Biocatalytic, stereoconvergent alkylation of (Z/E)-trisubstituted silyl enol ethers
The selective conversion of mixtures of Z/E alkenes into chiral products is a synthetic challenge. Biocatalytic strategies can transform isomeric...
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Protection of Oxidative Stress-induced DNA Damage and Apoptosis by Rosmarinic Acid in Murine Myoblast C2C12 Cells
Rosmarinic acid (RA) is a naturally occurring polyphenolic compound that has been applied as a therapeutic antioxidant. However, its action mechanism...
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Development of a cell line from skeletal trunk muscle of the fish Labeo rohita
Labeo rohita is a widely cultivated tropical freshwater carp and found in rivers of South Asian region. A new cell line, designated LRM, has been...
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Uranium enrichment performence and uranium stress mechanism of Deinococcus radiodurans
Deinococcus radioduran s (DR) was used as a biological adsorbent for uranium adsorption of low-concentration uranium wastewater.The enrichment...
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Evaluation of UV–B protective properties of leaves and seeds of Achyranthes aspera in Asian catfish Clarias batrachus (Linn.)
The ultraviolet–B (UV–B) radiation is harmful to the aquatic organisms. The UV–B protective properties of leaves and seeds of herb Achyranthes aspera ...
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Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds
Hydroxylated aromatic compounds exhibit exceptional biological activities. In the biosynthesis of these compounds, three types of hydroxylases are...
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Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2
Ferredoxins comprise a large family of iron–sulfur (Fe–S) proteins that shuttle electrons in diverse biological processes. Human mitochondria contain...
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Catharanthus roseus Monoterpenoid Indole Alkaloid Pathway Engineering in Yeast
Catharanthus roseus (L) G. Don, commonly known as Madagascar periwinkle, is a plant renowned for its ability to produce a wide range of bioactive...