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Elucidating the binding mechanism of a cholesterol absorption inhibitor with a serum albumin: spectroscopic, zeta potential, voltammetric and computational studies
Biomolecular binding of a potential drug, ezetimibe (EZT) with bovine serum albumin (BSA) was investigated by spectroscopic and electrochemical...
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Synthesis of novel dimers containing cholesterol and ergosterol using click reaction and their anti-proliferative effects
AbstractThis study aimed to achieve the synthesis of dimers containing cholesterol and ergosterol using click reaction and to perform biologic...
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Development of Non-enzymatic Cholesterol Electrochemical Sensor Based on Polyindole/Tungsten Carbide Nanocomposite
Non-enzymatic electrochemical sensor was developed for estimation of low-level cholesterol. Polyindole/tungsten carbide (PIN/WC) nanocomposite was...
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Pregnenolone and progesterone production from natural sterols using recombinant strain of Mycolicibacterium smegmatis mc2 155 expressing mammalian steroidogenesis system
BackgroundPregnenolone and progesterone are the life-important steroid hormones regulating essential vital functions in mammals, and widely used in...
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Gels as Templates for Nanotubes
The design of artificial models for “biomineralization” processes that utilize sol-gel polycondensation has led to a merging of inorganic materials...
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Sphincter of Oddi Dysfunction Induces Gallstone by Inhibiting the Expression of ABCB11 via PKC-α
The abnormal increase of Oddi sphincter pressure and total bile duct pressure may play an important role in the formation of cholesterol stones, but...
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Self-assembly of cholesterol end-capped polymer micelles for controlled drug delivery
BackgroundDuring the past few decades, drug delivery system (DDS) has attracted many interests because it could enhance the therapeutic effects of...
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Complexes of Anionic Cholesterol-Containing Liposomes and Cationic Chitosan Microparticles
AbstractThe preparation of multiliposomal complexes by adsorption of anionic cholesterol-containing liposomes on the surface of cationic chitosan...
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Nondestructive VIS/NIR spectroscopy estimation of intravitelline vitamin E and cholesterol concentration in hen shell eggs
AbstractDesigner hen shell eggs, with enhanced or reduced specific components, are used as part of a healthy diet, and such designer eggs must meet...
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Levels of monochloropropane-diol and glycidyl esters in heated palm oil and assessment of their risk in the animal model
3-monochloropropane-1,2-diol esters (3-MCPD-Es) , 2-monochloropropane-1,3-diol esters (2-MCPD-Es), and glycidyl esters (G-Es) are heat-induced...
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Antioxidant and Cardioprotective Property of Polyphenols from Natural Sources on Protein Denaturation and Vasorelaxation in Chick Embryo Model: A Replacing Study for Animal Model Testing
The aim of the study is focussed on investigating the dietary polyphenols and antioxidant potential of Nardostachys jatamansi rhizomes extract (NJRE)...
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Cationic Copolymerization of Cholesterol Vinyl Ether with Methyl Vinyl Sulfide: Towards New Biologically Active Oligomers
AbstractOligomers of cholesterol vinyl ether with methyl vinyl sulfide were synthesized in up to 81% yield ( M n up to 5700) by cationic...
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Functional Foods and Nutraceuticals as Immunity Boosters and in Combating Lifestyle Diseases
Immense number of biological active components are present in functional foods that are linked with the management of several chronic lifestyle...
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Allantoin, a Potential Metabolite That Promotes AMPK Phosphorylation and Suppresses Cholesterol Biosynthesis Via the Mevalonate Pathway and Bloch Pathway
This study aimed to evaluate the effect of probiotic administration on obese and ageing models. Sprague Dawley rats were subjected to high-fat diet...
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Control Phytophagous Nematodes By Engineering Phytosterol Dealkylation Caenorhabditis elegans as a Model
Plant-parasitic nematodes ingest and convert host phytosterols via dealkylation to cholesterol for both structural and hormonal requirements. The...
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Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands
The transient receptor potential vanilloid 2 (TRPV2) ion channel is a polymodal receptor widely involved in many physiological and pathological...
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Associations between dietary diversity and dyslipidemia among Japanese workers: cross-sectional study and longitudinal study findings
ObjectiveThe aim of this study was to determine the associations between dietary diversity and risk of dyslipidemia in Japanese workers.
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Consumer perception and physicochemical properties of crude groundnut oil in comparison with selected vegetable oil
This study investigated the consumer awareness, consumption pattern and the quality of unrefined groundnut oil in comparison with soybean, sesame oil...
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Cholesterol removal by selected metal–organic frameworks as adsorbents
The aim of this study was to investigate the cholesterol removal capacity of seven metal–organic frameworks (MOF) and to compare with active carbon...
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Potential use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and prevention method in viral infection
Cellular lipid membranes serve as the primary barrier preventing viral infection of the host cell and provide viruses with a critical initial point...
