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Vitamin A
Vitamin A is a vital nutrient for a variety of biological processes including vision, growth, reproduction, development and regulation of immune... -
Nonsense-Mediated mRNA Decay: Mechanistic Insights and Physiological Significance
Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved surveillance mechanism across eukaryotes and also regulates the expression of...
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Atmospheric Reactive Oxygen Species and Some Aspects of the Antiviral Protection at the Respiratory Epithelium
Abstract —The review summarizes literature data on molecular and biochemical mechanisms of nonspecific protection of respiratory epithelium. The...
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The application of CRISPR-Cas in disease diagnosis and treatment
Clustered regularly interspaced short palindromic repeat (CRISPR) has been gaining much attention in the modern medical field and has been widely...
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Nanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases
The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal strategy in the pursuit of refined treatment methodologies...
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Antimicrobial therapeutic protein extraction from fruit waste and recent trends in their utilization against infections
Fruits are a very good source of various nutrients that can boost overall human health. In these days, the recovery of therapeutic compounds from...
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Lumacaftor as a potential repurposed drug in targeting breast cancer stem cells: insights from in silico study
ContextBreast cancer stem cells (BCSCs) are a small subset of cells within breast tumors with characteristics similar to normal stem cells. Despite...
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Metabolomics Approach to Identify Biomarkers of Epidemic Diseases
Epidemic diseases are a major public health concern for the growing economic world. Several metabolomics analysis efforts have been put toward human... -
Genome Editing in the Synthetic Biology for Sustainable Production of Biomolecules
Site-specific modification of DNA/genetic material by insertion, deletion, and replacement of a gene is known as genome editing. Manipulation of the... -
Cytokine Response to Nanoparticles Bearing Nucleic Acid Cargo
Non-viral gene delivery systems have proved to be promising for treatment of various cancers and other diseases. They are actively explored in... -
Positive and negative aspects of bacteriophages and their immense role in the food chain
Bacteriophages infect and replicate inside a bacterial host as well as serve as natural bio-control agents. Phages were once viewed as nuisances that...
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Microbiologically Synthesized Nanoparticles and Their Role in Biofilm Inhibition
Much research is being done on alternative antibacterial therapies that replace or supplement conventional antibiotics since multidrug-resistant... -
Extracellular Communication in Bacteria
Populations of bacterial cells often coordinate their responses to changes in their local environmental conditions through “quorum sensing”, a... -
Additional Gene Therapeutic Platforms
AdditionalTherapeutic gene technologies are summarized here withOligonucleotide active use of CPPs, which are available to restore the missing gene... -
Analysis of Endogenous Metabolites in Human Matrices
For several decades, biological matrices have been used to assess the physiological conditions of organisms. The development of analytical techniques... -
Volatile Organic Compounds Emitted by Biological Matrices
This chapter describes volatile organic metabolites emitted from bacteria and tissue and existing in breath, urine, saliva, and fecal samples.... -
The Attenuating Effect of Curcumin-Loaded Gold Nanoparticles and Its Combination with Pluchea indica Root Extract on Kidney Stone Induced Male Wistar Rats
The focus of this research was to investigate the impact of combining curcumin-loaded gold nanoparticles (Au NPs) with P. indica root extracts on...
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Analysis of Endogenous Metabolites in Human Matrices
For several decades, biological matrices have been used to assess the physiological conditions of organisms. The development of analytical techniques... -
Volatile Organic Compounds Emitted by Biological Matrices
This chapter describes volatile organic metabolites emitted from bacteria and tissue and existing in breath, urine, saliva, and fecal samples.... -
Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response
The human pathogen Pseudomonas aeruginosa produces various 4(1 H )-quinolones with diverse functions. Among these, 2-nonyl-4(1 H )-quinolone (NQ) and its N ...