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Improved Sterilization Techniques for Successful In Vitro Micropropagation
Biotechnological solutions based on in vitro plant tissue culture paved the way for assessing desirable features by increasing the efficiency of in...
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Plant In Vitro Culture Factories for Pentacyclic Triterpenoid Production
Pentacyclic triterpenoids are a diverse subclass of naturally occurring terpenes with various biological activities and applications. These compounds...
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Specific Toxicity of Nanoparticles: A Review
Abstract―An overview of the specific toxicity of nanoparticles as of 2023 is provided. The methods of synthesis, structure and properties of...
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Assessment of Reproductive Toxicity
The utilization of animal models in order to assess hazard and risk to humans from exogenous substances continues to be the standard for protecting...
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The role of the electrokinetic charge of neurotrophis-based nanocarriers: protein distribution, toxicity, and oxidative stress in in vitro setting
BackgroundThe rational chemical design of nanoparticles can be readily controlled and optimized by quantitatively studying protein adsorption at...
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Synthesis of doxorubicin pro-drug nanoparticles based on poloxamer188 and studies on their in vivo bio-security and in vitro anti-tumor activities
The purpose of this study was to develop a novel glutathione (GSH)-responsible doxorubicin (DOX) pro-drug (poloxamer188-S-S-DOX, PSSD) nanoparticles...
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Extrapolation of cytotoxic masked effects in planar in vitro assays
The masking of specific effects in in vitro assays by cytotoxicity is a commonly known phenomenon. This may result in a partial or complete loss of...
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Assessment of acute oral toxicity of quercetin loaded alginate/chitosan nanoparticles: in vivo study
The present work explores the biocompatibility of the fabricated and optimized blank Alginate/chitosan nanoparticles (ALG/CSNPs) and quercetin loaded...
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In Vitro Cytotoxicity Testing of Food Packaging
Colorimetric assays with tetrazolium salts allow rapid evaluation of cytotoxicity endpoints. These assays are based on the ability of viable cells to...
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Contamination of ultraviolet absorbers in food: toxicity, analytical methods, occurrence and risk assessments
Ultraviolet (UV) absorbers are chemical substances that are widely used as defenses against the damaging effects of solar radiations. UV absorbers,...
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Tau Oligomers as Pathogenic Seeds: Preparation, Characterization, and Propagation In Vitro and In Vivo
Tau oligomers have been shown to be the main toxic tau species in several neurodegenerative disorders. To study tau oligomers, we have developed...
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Ammonium salts of microcrystalline cellulose-g-poly (acrylonitrile): toxicity, antioxidant and anti-inflammatory properties
Cellulose is an excellent starting material for the construction of bioactive polymers. In the present work, we have synthesized quaternized graft...
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In Vivo and In Vitro Biocompatibility Study of CuS Nanoparticles: Photosensitizer for Glioblastoma Photothermal Therapy
Although photothermal treatment (PTT) has made significant progress in the fight against cancer, certain types of malignant tumors are still...
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Toxicity of Nanomaterials: An Overview
Nanotechnology has attracted much attention due to its potential applications in diverse areas. Nanoparticles (NPs) have unique properties as...
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Melatonin as an Ameliorative Agent Against Cadmium- and Lead-Induced Toxicity in Fish: an Overview
AbstractDiverse anthropogenic activities and lack of knowledge on its consequences have promoted serious heavy metal contaminations in different...
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The bromoporphyrins as promising anti-tumor photosensitizers in vitro
The synthesis of ideal photosensitizers (PSs) is considered to be the most significant bottleneck in photodynamic therapy (PDT). To discover novel...
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Preparation of oral nanoemulsion drug delivery system loaded with punicalagin: in vitro antibacterial activity, drug release, and cell safety studies
The objective of the present study was to develop a W/O/W nanoemulsion (NE) drug delivery system loaded with punicalagin (PGN) for oral delivery and...
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Eucalyptus Oils Phytochemical Composition in Correlation with Their Newly Explored Anti-SARS-CoV-2 Potential: in Vitro and in Silico Approaches
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the latest arisen contagious respiratory pathogen related to the global outbreak of...
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Acute toxicity study of onion peel-derived gold nano-bioconjugate
The acute anti-inflammatory activity of onion peel-derived gold nano-bioconjugate was already established earlier. The current study was aimed to...
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Anti-proliferative effect of leaf phytochemicals of soursop (Annona muricata L.) against human osteosarcoma in vitro
Leaves of soursop ( Annona muricata ) is a potential anti-cancer agent. However, there is no report on the effect of soursop leaf phytochemicals...
