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Chapter
Key Scientific Issues in Research for Quality Control of Chinese Medicines
Quality control is the key for modernization and internationalization of traditional Chinese medicines (TCMs). Besides techniques, key scientific issues in research on quality control of TCMs are crucial for w...
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Chapter
Infrared Spectroscopy for Quality Control of Chinese Medicines
Infrared spectra of solid, liquid, and gas samples can be measured without separation or extraction. Most organic and inorganic molecules can generate fingerprint-like infrared spectral signals without derivat...
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Knock-Out and Knock-In Technique for Finding Integrative Components that Contribute to Effect of Chinese Medicines
Elucidating the effective constituents of Chinese medicine (CM) is a big challenge due to its complex constituents and diverse interactions. Knock-out/knock-in technique is a promising strategy to reveal the i...
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Chapter
HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines
Active compounds derived from Chinese medicines (CMs) have already illustrated immense therapeutic potential over an array of different diseases, and served as an inexhausted source for drug discovery and deve...
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Chapter
CE and CE-MS in Quality Control of Chinese Medicines
Analysis of active components or dubious adulterants in Chinese medicines is often somewhat problematic due to the highly complex nature of the sample matrices, which makes the identification of individual con...
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Chapter
Omics in Quality Research of Chinese Medicines
The quality of Chinese medicines (CMs) is the basis to guarantee the clinical safety, effectiveness, and controllability of medicinal materials. It is the lifeline to promoting sustainable development of the C...
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Chromatographic Separation with On-Line (Bio)Assay, a Rapid Technique for Screening Active Compounds from Chinese Medicines
Due to the complex compositions of Chinese medicine (CM), how to rapidly and efficiently discovery the biologically active components from them is a huge challenge. Traditionally, tedious extraction-isolation-...
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Chapter
Applications of Pressurized Liquid Extraction in Quality Control of Traditional Chinese Medicines
For many bioactive chemicals contained in traditional Chinese medicines, pressurized liquid extraction has become a preferred green extraction method. This review goes over the extraction principles and how to...
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Chapter
Advance and Challenge of Component-Effect Relationship in the Discovery of Active Components from Chinese Medicines
Active ingredients discovery has always been a hot topic for the research of Chinese medicines (CMs). The component-effect relationship is one of the widely used strategies for finding herbal active ingredient...
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Chapter
Application of Thin-Layer Chromatography in Quality Control of Chinese Medicines
Thin-layer chromatography is a conventional analytical method in quality control of traditional Chinese medicines. Many advantageous characteristics make it an important technology in quality research. However...
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Chapter
Molecular Docking for Virtual Screening of Potential Active Ingredients in Chinese Medicines
Traditional Chinese medicine (TCM) plays a vital role in the prevention and treatment of various diseases for thousands of years. It is of great significance to elucidate the effective material basis and relat...
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Chapter
Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry in Quality Control of Chinese Medicines
Gas chromatography (GC) is a well-known and widely employed technique for separation and analysis of the gaseous and volatile components. Modern GC technique was firstly invented by James and Martin in 1952 an...
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Chapter
Conventional Methods of Sample Preparation for Quality Control of Chinese Medicines
Sample preparation is an important and time-consuming step in quality control of herbal medicine. Due to the state of most solid samples, their constituents should be transferred to solvents from the matrix be...
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Chapter
Quality Control of Chinese Medicines Using UPLC–MS
Quality control of Chinese medicines (CMs) is a difficult work because of their intrinsic complexity. UPLC-MS is at the forefront of this crucial challenge due to its prominent performance in qualitative and q...
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Chapter
Chemometrics in Quality Control of Traditional Chinese Medicines
The modernization and globalization of traditional Chinese medicines (TCMs) require the implementation of a robust quality control system, and the application of modern theories and technologies in analytical ...
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Chapter
Quantitative NMR in Quality Control
The scope of the chapter is based on surveys with a total of >1000 responses. So, the scope of this chapter focuses on certain specific requirements from the global qNMR community. Specifically, this chapter o...
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Chapter
Strategies for Quality Control of Polysaccharides in Chinese Medicines
Polysaccharides with multiple biological activities are usually considered as one of the major bioactive compounds in Chinese medicines (CMs). At present, the development of drugs and functional foods related ...
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Chapter
Bio-Specific Extraction/Receptor Fishing for Screening of Active Components in Chinese Medicines
In this chapter, the principles and processes of bio-specific extraction/receptor fishing, such as equilibrium dialysis, centrifugation, and material-based ligand screening assay, are briefly introduced, respe...
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Chapter
Application of Supercritical Fluid Extraction in Quality Control of Chinese Medicines
Traditional Chinese medicine (TCMs), as an important branch of medicine, has been used in the treatment of various diseases in East Asia for thousands of years. However, due to the complexity of TCMs, the deve...