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  1. KDM4 Demethylases: Structure, Function, and Inhibitors

    KDM4 histone demethylases mainly catalyze the removal of methyl marks from H3K9 and H3K36 to epigenetically regulate chromatin structure and gene...
    Yuanyuan Jiang, Lanxin Liu, Zeng-Quan Yang in Targeting Lysine Demethylases in Cancer and Other Human Diseases
    Chapter 2023
  2. Structure, Function and Distribution of ATP8A2 in Human and Mice

    Abstract

    ATP8A2 can translocate phospholipids from exoplasmic to the cytoplasmic leaflets to establish and maintain the lipid asymmetry between the...

    Junyuan Zeng, Junhua Yang in Neurochemical Journal
    Article 30 August 2023
  3. High-throughput biochemistry in RNA sequence space: predicting structure and function

    RNAs are central to fundamental biological processes in all known organisms. The set of possible intramolecular interactions of RNA nucleotides...

    Emil Marklund, Yuxi Ke, William J. Greenleaf in Nature Reviews Genetics
    Article 12 January 2023
  4. Structure-function Studies of GABA (A) Receptors and Related computer-aided Studies

    The γ-aminobutyric acid type A receptor (GABA (A) receptor) is a membrane protein activated by the neurotransmitter GABA. Structurally, this major...

    Fatin H. Mohamad, Muhamad Arif Mohamad Jamali, Ahmad Tarmizi Che Has in Journal of Molecular Neuroscience
    Article 26 September 2023
  5. The microsporidian polar tube: origin, structure, composition, function, and application

    Microsporidia are a class of obligate intracellular parasitic unicellular eukaryotes that infect a variety of hosts, even including humans. Although...

    Yuqing Chen, Qing Lv, ... Zeyang Zhou in Parasites & Vectors
    Article Open access 30 August 2023
  6. The Aging Patterns of Brain Structure, Function, and Energy Metabolism

    The normal aging process brings changes in brain structure, function, and energy metabolism, which are presumed to contribute to the age-related...
    Mingxi Dang, Feng Sang, ... Yao**g Chen in Cognitive Aging and Brain Health
    Chapter 2023
  7. A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels

    The greater thoracic vessels are central to a well-functioning circulatory system and are often targeted in congenital heart surgeries, yet the...

    Abhay B. Ramachandra, Cristina Cavinato, Jay D. Humphrey in Annals of Biomedical Engineering
    Article 16 January 2024
  8. Pseudomonas aeruginosa Virulence Factors and Biofilm Components: Synthesis, Structure, Function and Inhibitors

    Pseudomonas aeruginosa is a versatile opportunistic bacterium reasons for hospital-acquired infections specifically to the patients suffering from...
    Mahima S. Mohan, Simi Asma Salim, ... Siddhardha Busi in ESKAPE Pathogens
    Chapter 2024
  9. Function and structure of bradykinin receptor 2 for drug discovery

    Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that regulates the cardiovascular system as a vasodepressor....

    **-kang Shen, Hai-tao Zhang in Acta Pharmacologica Sinica
    Article 08 September 2022
  10. Structure and Function of Immune System

    The lymphoreticular system consists of intricate networking of cells with diverse morphology, which spreads across various organs and tissues of the...
    Subhash Chandra Parija in Textbook of Microbiology and Immunology
    Chapter 2023
  11. Intergenerational transmission of brain structure and function in humans: a narrative review of designs, methods, and findings

    Children often show cognitive and affective traits that are similar to their parents. Although this indicates a transmission of phenotypes from...

    Charlotte Constant-Varlet, Tomoya Nakai, Jérôme Prado in Brain Structure and Function
    Article 07 May 2024
  12. Integrating brain function and structure in the study of the human attentional networks: a functionnectome study

    Attention is a heterogeneous function theoretically divided into different systems. While functional magnetic resonance imaging (fMRI) has...

    Mar Martín-Signes, Pedro M. Paz-Alonso, ... Ana B. Chica in Brain Structure and Function
    Article Open access 06 July 2024
  13. Glial Cell Modulation of Dendritic Spine Structure and Synaptic Function

    Glia comprise a heterogeneous group of cells involved in the structure and function of the central and peripheral nervous system. Glial cells are...
    Alberto A. Rasia-Filho, Maria Elisa Calcagnotto, Oliver von Bohlen und Halbach in Dendritic Spines
    Chapter 2023
  14. Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery

    Hereditary genetic diseases, cancer, and infectious diseases are affecting global health and become major health issues, but the treatment...

    Da Sun, Zheng-Rong Lu in Pharmaceutical Research
    Article 04 January 2023
  15. MSCs overexpressing GDNF restores brain structure and neurological function in rats with intracerebral hemorrhage

    Mesenchymal stem cells (MSCs) have been applied in transplantation to treat intracerebral hemorrhage (ICH) but with limited efficacy. Accumulated...

    **aoqian Jiang, Ling Zhou, ... Chaoxian Yang in Molecular Biomedicine
    Article Open access 27 November 2023
  16. Effect of spaceflight experience on human brain structure, microstructure, and function: systematic review of neuroimaging studies

    Spaceflight-induced brain changes have been commonly reported in astronauts. The role of microgravity in the alteration of the brain structure,...

    Sahar Rezaei, Homa Seyedmirzaei, ... Mohammad Hadi Aarabi in Brain Imaging and Behavior
    Article Open access 22 May 2024
  17. Structure–function relationship of the pituitary gland in anorexia nervosa and intense physical activity

    Patients with Anorexia Nervosa (AN) and athletes share intense physical activity and pituitary hormonal disturbances related to absolute (AN) or...

    Manel Merabet, Natacha Germain, ... Fabien C. Schneider in Brain Structure and Function
    Article 08 December 2023
  18. Klebsiella pneumoniae Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors

    Klebsiella pneumoniae is a Gram-negative pathogen capable of causing a diverse array of infections in humans. It belongs to the group of ESKAPE...
    Bicky Jerin Joseph, Maya Mathew, ... E. K. Radhakrishnan in ESKAPE Pathogens
    Chapter 2024
  19. Structure and function of the parvoviral NS1 protein: a review

    Parvoviruses possess a single-stranded DNA genome of about 5 kb, which contains two open reading frames (ORFs), one encoding nonstructural (NS)...

    Qianqian **e, Jigui Wang, ... Weiquan Liu in Virus Genes
    Article 17 October 2022
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