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KDM4 Demethylases: Structure, Function, and Inhibitors
KDM4 histone demethylases mainly catalyze the removal of methyl marks from H3K9 and H3K36 to epigenetically regulate chromatin structure and gene... -
Structure, Function and Distribution of ATP8A2 in Human and Mice
AbstractATP8A2 can translocate phospholipids from exoplasmic to the cytoplasmic leaflets to establish and maintain the lipid asymmetry between the...
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High-throughput biochemistry in RNA sequence space: predicting structure and function
RNAs are central to fundamental biological processes in all known organisms. The set of possible intramolecular interactions of RNA nucleotides...
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Structure-function Studies of GABA (A) Receptors and Related computer-aided Studies
The γ-aminobutyric acid type A receptor (GABA (A) receptor) is a membrane protein activated by the neurotransmitter GABA. Structurally, this major...
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The microsporidian polar tube: origin, structure, composition, function, and application
Microsporidia are a class of obligate intracellular parasitic unicellular eukaryotes that infect a variety of hosts, even including humans. Although...
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The Aging Patterns of Brain Structure, Function, and Energy Metabolism
The normal aging process brings changes in brain structure, function, and energy metabolism, which are presumed to contribute to the age-related... -
A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels
The greater thoracic vessels are central to a well-functioning circulatory system and are often targeted in congenital heart surgeries, yet the...
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Pseudomonas aeruginosa Virulence Factors and Biofilm Components: Synthesis, Structure, Function and Inhibitors
Pseudomonas aeruginosa is a versatile opportunistic bacterium reasons for hospital-acquired infections specifically to the patients suffering from... -
Function and structure of bradykinin receptor 2 for drug discovery
Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that regulates the cardiovascular system as a vasodepressor....
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Structure and Function of Immune System
The lymphoreticular system consists of intricate networking of cells with diverse morphology, which spreads across various organs and tissues of the... -
Intergenerational transmission of brain structure and function in humans: a narrative review of designs, methods, and findings
Children often show cognitive and affective traits that are similar to their parents. Although this indicates a transmission of phenotypes from...
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Integrating brain function and structure in the study of the human attentional networks: a functionnectome study
Attention is a heterogeneous function theoretically divided into different systems. While functional magnetic resonance imaging (fMRI) has...
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Glial Cell Modulation of Dendritic Spine Structure and Synaptic Function
Glia comprise a heterogeneous group of cells involved in the structure and function of the central and peripheral nervous system. Glial cells are... -
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery
Hereditary genetic diseases, cancer, and infectious diseases are affecting global health and become major health issues, but the treatment...
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MSCs overexpressing GDNF restores brain structure and neurological function in rats with intracerebral hemorrhage
Mesenchymal stem cells (MSCs) have been applied in transplantation to treat intracerebral hemorrhage (ICH) but with limited efficacy. Accumulated...
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Effect of spaceflight experience on human brain structure, microstructure, and function: systematic review of neuroimaging studies
Spaceflight-induced brain changes have been commonly reported in astronauts. The role of microgravity in the alteration of the brain structure,...
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Structure–function relationship of the pituitary gland in anorexia nervosa and intense physical activity
Patients with Anorexia Nervosa (AN) and athletes share intense physical activity and pituitary hormonal disturbances related to absolute (AN) or...
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Klebsiella pneumoniae Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Klebsiella pneumoniae is a Gram-negative pathogen capable of causing a diverse array of infections in humans. It belongs to the group of ESKAPE... -
Structure and function of the parvoviral NS1 protein: a review
Parvoviruses possess a single-stranded DNA genome of about 5 kb, which contains two open reading frames (ORFs), one encoding nonstructural (NS)...