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Implementing Nanovesicles for Boosting the Skin Permeation of Non-steroidal Anti-inflammatory Drugs
The consumption of non-steroidal anti-inflammatory drugs (NSAIDs) have increased lately around the world, as they are considered essential and...
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Non-aspirin non-steroidal anti-inflammatory drugs in colorectal cancer: a review of clinical studies
Colorectal cancer (CRC) chemoprevention is an area of interest. Non-steroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory agents which...
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A story of the potential effect of non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson’s disease: beneficial or detrimental effects
Parkinson’s disease (PD) is an advanced neurodegenerative disease (NDD) caused by the degeneration of dopaminergic neurons (DNs) in the substantia...
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The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration
Periodontitis is the sixth most prevalent chronic disease globally and places significant burdens on societies and economies worldwide. Behavioral...
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Spectroscopic and Molecular Docking Studies of the Interaction of Non-steroidal Anti-inflammatory Drugs with a Carrier Protein: an Interesting Case of Inner Filter Effect and Intensity Enhancement in Protein Fluorescence
Interaction of diclofenac and indomethacin with lysozyme was studied using several spectroscopic and molecular docking methods. Difference UV–visible...
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Colorectal Cancer Survivors’ Receptivity toward Genomic Testing and Targeted Use of Non-Steroidal Anti-Inflammatory Drugs to Prevent Cancer Recurrence
Genomic testing and targeted use of non-steroidal anti-inflammatory drugs (NSAIDs) may mitigate cancer recurrence risks. This study examines...
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Non-steroidal anti-inflammatory drug target gene associations with major depressive disorders: a Mendelian randomisation study integrating GWAS, eQTL and mQTL Data
Previous observational studies reported associations between non-steroidal anti-inflammatory drugs (NSAIDs) and major depressive disorder (MDD),...
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Non-Steroidal Anti-Inflammatory Medicines
Nearly 30 million people in the world take NSAIM drugs daily for different painful conditions and fever. NSAIMs are extensively prescribed worldwide.... -
Twin Screw Melt Granulation: Alternative Approach for Improving Solubility and Permeability of a Non-steroidal Anti-inflammatory Drug Ibuprofen
The current research is focused on investigating the suitability of the twin screw melt granulation (TSMG) approach for improving the solubility of a...
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Apigenin attenuates indomethacin-induced gastric ulcer in rats: emphasis on antioxidant, anti-inflammatory, anti-apoptotic, and TGF-β1 enhancing activities
Gastric ulcer disease is associated with significant morbidity and mortality rates. The most two common causes of the ulcer are Helicobacter pylori ...
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Exploring the Gastroprotective, Ulcer Healing and Chemopreventive Properties of Nitric Oxide-Releasing Nonsteroidal Anti-inflammatory Drugs
Nitric oxide (NO) is a pleiotropic endogenous mediator in the gastrointestinal (GI) tract that is produced by the three NO-synthase (NOS) enzymes;... -
Maternal non-steroidal anti-inflammatory drug exposure during pregnancy and risk of miscarriage: a systematic review and meta-analysis
BackgroundNumerous studies have suggested that non-steroidal anti-inflammatory drugs (NSAIDs) might be associated with increased risk of miscarriage....
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Animal Models of Pain and Anti-inflammatory Treatments
Animal models are critical to the field of pain research, both for the study of mechanisms and the testing of novel therapeutics. Unfortunately, many... -
Effect of the Non-steroidal Anti-inflammatory Drug Diclofenac on Ischemia–Reperfusion Injury in Rat Liver: A Nitric Oxide-Dependent Mechanism
Ischemia/reperfusion injury (IRI) is an inevitable complication of liver surgery and transplantation. The purpose of this study was to examine the...
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Multifaceted Molecular Targets of Anti-Inflammatory Agents from Ayurvedic Plants
The relationship between prolonged inflammation and the occurrence of different fatal diseases like cancer was first identified in the nineteenth... -
Recent advances in anti-inflammatory active components and action mechanisms of natural medicines
Inflammation is a series of reactions caused by the body’s resistance to external biological stimuli. Inflammation affects the occurrence and...
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Effects of nitro-butoxyl- and butyl-esters of non-steroidal anti-inflammatory drugs compared with parent compounds on the contractility of digital arterial smooth muscle from the fallow deer (Dama dama)
BackgroundNon-steroidal anti-inflammatory drugs (NSAIDs) are a major cause of upper gastro-intestinal (GI) ulceration and bleeding as well as...
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The potential impact of dietary choices on melanoma risk: an anti-inflammatory diet
The role of inflammation in the aetiology of cancer is recognized. However, no study yet examined the association between an anti-inflammatory diet...
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Anti-inflammatory peptide therapeutics and the role of sulphur containing amino acids (cysteine and methionine) in inflammation suppression: A review
BackgroundInflammation serves as our body’s immune response to combat infections, pathogens, viruses, and external stimuli. Inflammation can be...