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Autophagy in Embryonic Stem Cells and Neural Stem Cells
AutophagyAutophagy is a conserved cytoprotective catabolic pathway that plays a crucial role in cellular turnover and homeostasis in eukaryotic...
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SOX5 Attenuates Toxicity in Neural Stem Cells Induced by Sevoflurane Anesthesia via Regulating the PI3K/AKT Pathway
AbstractDifferentiation and self-renewal capacity of neural stem cells are essential for the development and function of brain. Anesthesia exposure...
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Induced Mesenchymal Stem Cells-Small Extracellular Vesicles Alleviate Post-stroke Cognitive Impairment by Rejuvenating Senescence of Neural Stem Cells
Ischemic stroke is typified by hypoxia and a cascade of pathophysiological events, including metabolic dysfunction, ionic dysregulation,...
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Stem Cell Exosomes Improve Survival of Neural Stem Cells after Radiation Exposure
The death of neural stem cells in the hippocampus during radiation therapy of brain tumors leads to neurogenesis impairment and the development of...
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Human Induced Pluripotent Stem Cells
This volume explores the latest developments in the field and showcases the vast potential of human induced pluripotent stem cells (hiPSCs) in...
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Human induced neural stem cells support functional recovery in spinal cord injury models
Spinal cord injury (SCI) is a clinical condition that leads to permanent and/or progressive disabilities of sensory, motor, and autonomic functions....
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Quiescent Adult Neural Stem Cells: Developmental Origin and Regulatory Mechanisms
The existence of neural stem cells (NSCs) in the adult mammalian nervous system, although small in number and restricted to the sub-ventricular zone...
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Overview: Cancer Stem Cells
Cancer has become a global issue and retains a central place in fatality rates among the wide variety of diseases known the world over, and the...
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Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases
Mitochondria are cytoplasmic organelles having a fundamental role in the regulation of neural stem cell (NSC) fate during neural development and...
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Neural Stem/Progenitor Cell (NSPC) Extraction and Culture
Neural stem–progenitor cells (NSPCs) are multipotent, self-renewing cells that generate radial glial cells (RGC). RGCs then give rise to neurons and...
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Chronic unpredictable stress induces autophagic death of adult hippocampal neural stem cells
Chronic psychological stress is a critical factor for neurological complications like anxiety disorders, dementia, and depression. Our previous...
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Neural Stem Cells and Brain Tumour Models in Drosophila
During development organs and tissues grow in size. This growth can be achieved either by increasing the size of individual cells or by increasing...
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Neural Progenitor Cells Methods and Protocols
This updated edition collects cutting-edge techniques used to study neural stem and progenitor cells as well as the brain microenvironment. Featuring...
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Improved Survival and Regeneration of Irradiated Mouse Neural Stem Cells after Co-Culturing with Non-Irradiated Mouse Neural Stem Cells or Mesenchymal Stem Cells from the Adipose Tissue
We studied the effect of neural stem cells (NSC) and mesenchymal stem cells (MSC) from mouse adipose tissue on survival, clonogenic activity, and...
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Ultra-Low-Dose UV-C Photo-stimulation Promotes Neural Stem Cells Differentiation via Presenilin 1 Mediated Notch and β-Catenin Activation
Light-based photo-stimulation has demonstrated promising effects on stem cell behavior, particularly in optimizing neurogenesis. However, the precise...
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Neural Stem Cells in Cerebral Cortex Development
Neural stem cells (NSCs) in the develo** neuroepithelium, as well as the progenitors they generate, eventually give rise to all the neurons of the...
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Monitoring Autophagy in Neural Stem and Progenitor Cells
Autophagy is a critical cellular program that is necessary for cellular survival and adaptation to nutrient and metabolic stress. In addition to...
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Depletion of transit amplifying cells in the adult brain does not affect quiescent neural stem cell pool size
Neural stem cells (NSCs) are maintained in the adult mammalian brain throughout the animal’s lifespan. NSCs in the subependymal zone infrequently...
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A Tale of Two: When Neural Stem Cells Encounter Hypoxia
Normoxia is defined as an oxygen concentration of 20.9%, as in room air, whereas hypoxia refers to any oxygen concentration less than this. Any...
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Neural Stem Cells in Cerebral Cortex Development
Neural stem cells (NSCs) in the develo** neuroepithelium, as well as the progenitors they generate, eventually give rise to all the neurons of the...