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Mass screening and treatment (MSaT) for identifying and treating asymptomatic cases of malaria-malaria elimination demonstration project (MEDP), Mandla, Madhya Pradesh
BackgroundMass screening and treatment (MSaT) aims at reducing the spread of malaria in communities by identifying and treating infected persons...
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Screening and Clinical Verification of Extracellular Vesicle Biomarkers
Extracellular vesicles (EVs), lipid bilayer-encapsulated membrane particles carrying proteins, lipids, nucleic acids, and sugars, are shed by most...
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Feasibility and applicability of self-sampling based online cervical cancer screening: findings from the China online cervical cancer screening trial
ObjectiveThis study aims to evaluate the feasibility and applicability of an online cervical cancer screening program using a website as the public...
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Exploring hematopoiesis in zebrafish using forward genetic screening
Zebrafish have emerged as a powerful animal model for investigating the genetic basis of hematopoiesis. Owing to its close genetic and developmental...
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High-Resolution Mass Spectrometry in Identification of New Analytes & Metabolites
Numerous forensic institutes including the National Board of Forensic Medicine in Sweden have been using high-resolution mass spectrometry to...
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Molecular Dynamics as a Tool for Virtual Ligand Screening
Rational drug design is essential for new drugs to emerge, especially when the structure of a target protein or nucleic acid is known. To that...
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Screening method toward ClbP-specific inhibitors
BackgroundColibactin is a genotoxin produced by Escherichia coli and other Enterobacteriaceae that is believed to increase the risk of colorectal...
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MALDI-TOF Mass Spectrometry-Based Assay for Measuring Covalent Target Engagement of KRAS G12C Inhibitors
MALDI-TOF mass spectrometry enables high-throughput screening of covalent fragment libraries and SAR compound progressions of selective KRAS G12C...
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Genomic newborn screening for rare diseases
Rare diseases are a leading cause of infant mortality and lifelong disability. To improve outcomes, timely diagnosis and effective treatments are...
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A retrospective analysis of MS/MS screening for IEM in high-risk areas
Inborn errors of metabolism (IEM) can lead to severe motor and neurological developmental disorders and even disability and death in children due to...
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Colorectal cancer screening: results from the World Trade Center Health Registry cohort
PurposeLittle is known about colorectal cancer screening in 9/11 World Trade Center (WTC)-exposed populations. We utilized survey data from the WTC...
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Mass spectrometric profiling of tryptic digests of trifluoroethanol extracts from core needle biopsies of breast cancer tissues is a viable sample screening tool for biomarker discovery
Application of classifying limited sampling biopsies by matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) based mass spectral...
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Screening for Antibody Specificity and Sensitivity with ELISA
Monoclonal antibodies (MAbs) can be used to detect and quantify protein biomarker antigens (Ag). Systematic screening with an enzyme-linked...
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Inequalities in cancer screening participation between adults with and without severe mental illness: results from a cross-sectional analysis of primary care data on English Screening Programmes
BackgroundPeople with severe mental illness (SMI) are 2.5 times more likely to die prematurely from cancer in England. Lower participation in...
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Peptide-encoding mRNA barcodes for the high-throughput in vivo screening of libraries of lipid nanoparticles for mRNA delivery
Develo** safe and effective nanoparticles for the delivery of messenger RNA (mRNA) is slow and expensive, partly due to the lack of predictive...
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Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies
Prenatal cell-free DNA (cfDNA) screening uses extracellular fetal DNA circulating in the peripheral blood of pregnant women to detect prevalent fetal...
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Screening and diagnosis of cardiovascular disease using artificial intelligence-enabled cardiac magnetic resonance imaging
Cardiac magnetic resonance imaging (CMR) is the gold standard for cardiac function assessment and plays a crucial role in diagnosing cardiovascular...
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Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role?
BackgroundIn the United Kingdom (UK), cancer screening invitations are based on general practice (GP) registrations. We hypothesize that GP...
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An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score
Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H 2 ...
