Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2797)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (25 protocols)
Keywords
About this book
This volume details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, KRAS: Methods and Protocols aims to provide methods that will be instrumental in the development of future clinically approved KRAS therapeutics.
Editors and Affiliations
Bibliographic Information
Book Title: KRAS
Book Subtitle: Methods and Protocols
Editors: Andrew G. Stephen, Dominic Esposito
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-3822-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Leios Biomedical Research, Inc. 2024
Hardcover ISBN: 978-1-0716-3821-7Published: 04 April 2024
Softcover ISBN: 978-1-0716-3824-8Due: 07 July 2024
eBook ISBN: 978-1-0716-3822-4Published: 03 April 2024
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 365
Number of Illustrations: 14 b/w illustrations, 69 illustrations in colour