Search
Search Results
-
Increase in choroidal thickness after blue light stimulation of the blind spot in young adults
BackgroundBlue light activates melanopsin, a photopigment that is expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs). The...
-
The cognitive impact of light: illuminating ipRGC circuit mechanisms
Ever-present in our environments, light entrains circadian rhythms over long timescales, influencing daily activity patterns, health and performance....
-
Intrinsically Photosensitive Retinal Ganglion Cells: Assessment of Their Influence on Pupillary Responses in Primates
Pupillary responses in primates are driven by melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) that project to the...
-
Patch-Clamp Electrophysiological Analysis of Murine Melanopsin Neurons
Intrinsically photosensitive retinal ganglion cells (ipRGCs) regulate diverse aspects of mammalian physiology, including the synchronization of...
-
Cell-specific localization of β-synuclein in the mouse retina
β-synuclein, a member of the synuclein family, is frequently co-expressed with α-synuclein in the neural system, where it serves to inhibit abnormal...
-
A Comprehensive Overview of the Neural Mechanisms of Light Therapy
Light is a powerful environmental factor influencing diverse brain functions. Clinical evidence supports the beneficial effect of light therapy on...
-
Effects of different light incident angles via a head-mounted device on the magnitude of nocturnal melatonin suppression in healthy young subjects
Bright light is a primary zeitgeber (synchronizer) for the central circadian pacemaker in humans. Recently, head-mounted devices for light therapy...
-
Review on age-related differences in non-visual effects of light: melatonin suppression, circadian phase shift and pupillary light reflex in children to older adults
Physiological effects of light exposure in humans are diverse. Among them, the circadian rhythm phase shift effect in order to maintain a 24-h cycle...
-
Methods to Identify Rat and Mouse Retinal Ganglion Cells in Retinal Flat-Mounts
The identification of distinct retinal ganglion cell (RGC) populations in flat-mounted retinas is key to investigating pathological or...
-
Differences in the pupillary responses to evening light between children and adolescents
BackgroundIn the mammalian retina, intrinsically-photosensitive retinal ganglion cells (ipRGC) detect light and integrate signals from rods and cones...
-
-
Non-visual Opsins and Novel Photo-Detectors in the Vertebrate Inner Retina Mediate Light Responses Within the Blue Spectrum Region
In recent decades, a number of novel non-visual opsin photopigments belonging to the family of G protein- coupled receptors, likely involved in a...
-
-
The Role of Retinal Dysfunction in Myopia Development
Myopia is a refractive disorder arising from a mismatch between refractive power and relatively long axial length of the eye. With its dramatically...
-
The Suprachiasmatic Nucleus and the Circadian Timekee** System of the Body
We humans are diurnal – active in the day and asleep at night. Along with this pattern of rest and activity are many other timed processes of which...
-
Spectroscopic Analysis of Wavelength Sensitivities of Opsin-Type Photoreceptor Proteins
The opsin family is a group of photoreceptive proteins that bind retinal as their chromophore. A growing number of opsin-encoding genes have been...
-
Distribution and synaptic organization of substance P-like immunoreactive neurons in the mouse retina
Substance P (SP), a neuroprotective peptidergic neurotransmitter, is known to have immunoreactivity (IR) localized to amacrine and/or ganglion cells...
-
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in irreversible vision loss due to the mammalian central nervous...
-
Crucial role of TFAP2B in the nervous system for regulating NREM sleep
The AP-2 transcription factors are crucial for regulating sleep in both vertebrate and invertebrate animals. In mice, loss of function of the...
-
Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development
BackgroundMelanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) respond directly to light and have been shown to...
