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Induction of excitatory brain state governs plastic functional changes in visual cortical topology
Adult visual plasticity underlying local remodeling of the cortical circuitry in vivo appears to be associated with a spatiotemporal pattern of...
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Resting-state functional connectivity in an auditory network differs between aspiring professional and amateur musicians and correlates with performance
Auditory experience-dependent plasticity is often studied in the domain of musical expertise. Available evidence suggests that years of musical...
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Environmental Chemicals as Plasticity Disruptors
The organism has plasticity consisting of several plasticities for homeostasis. In this chapter, developmental plasticity is introduced, particularly... -
Decoding auditory deprivation: resting-state fMRI insights into deafness and brain plasticity
Deafness, as a profound manifestation of sensory deprivation, prompts a cascade of intricate cerebral adaptations. In this study, involving 35 deaf...
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Resting-state functional-MRI in iNPH: can default mode and motor networks changes improve patient selection and outcome? Preliminary report
BackgroundIdiopathic normal pressure hydrocephalus (iNPH) is a progressive and partially reversible form of dementia, characterized by impaired...
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Treg plasticity and human diseases
IntroductionAs a subset of CD4 + T cells, regulatory T cells (Tregs) with the characteristic expression of transcription factor FOXP3 play a key role...
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Executive functioning, ADHD symptoms and resting state functional connectivity in children with perinatal stroke
Perinatal stroke describes a group of focal, vascular brain injuries that occur early in development, often resulting in lifelong disability. Two...
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Deciphering cellular plasticity in pancreatic cancer for effective treatments
Cellular plasticity and therapy resistance are critical features of pancreatic cancer, a highly aggressive and fatal disease. The pancreas, a vital...
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Sex differences of signal complexity at resting-state functional magnetic resonance imaging and their associations with the estrogen-signaling pathway in the brain
Sex differences in the brain have been widely reported and may hold the key to elucidating sex differences in many medical conditions and drug...
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Metabolic Plasticity in Develo** and Aging Brain
Abstract —Brain plasticity is a fundamental phenomenon based on various types of intercellular interactions (synaptic activity, neuritogenesis,...
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Altered stability of dynamic brain functional architecture in primary open-angle glaucoma: a surface-based resting-state fMRI study
Delineating the neuropathological characteristics of primary open-angle glaucoma (POAG) is critical for understanding its pathophysiology. While...
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Multiomics approach towards characterization of tumor cell plasticity and its significance in precision and personalized medicine
Cellular plasticity refers to the ability of cells to change their identity or behavior, which can be advantageous in some cases (e.g., tissue...
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Cancer cell plasticity, stem cell factors, and therapy resistance: how are they linked?
Cellular plasticity can occur naturally in an organism and is considered an adapting mechanism during the developmental stage. However, abnormal...
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Genetic constraints in genes exhibiting splicing plasticity in facultative diapause
Phenotypic plasticity is produced and maintained by processes regulating the transcriptome. While differential gene expression is among the most...
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Microglial diversity along the hippocampal longitudinal axis impacts synaptic plasticity in adult male mice under homeostatic conditions
The hippocampus is a plastic brain area that shows functional segregation along its longitudinal axis, reflected by a higher level of long-term...
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Epigenetics and Brain Plasticity: Back to Function
Throughout our entire life, our brain is constantly shaped by the experience of both the outer and the inner environments. Sensory perceptions, as... -
Overnight neuronal plasticity and adaptation to emotional distress
Expressions such as ‘sleep on it’ refer to the resolution of distressing experiences across a night of sound sleep. Sleep is an active state during...
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Astrocytes: The Rising Stars that Regulate Synaptic Plasticity and Long-Term Memory Formation
For decades, our understanding of the mechanisms underlying long-term synaptic plasticity and memory is largely limited to the roles played by... -
Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance
Cancer is a complex disease displaying a variety of cell states and phenotypes. This diversity, known as cancer cell plasticity, confers cancer cells...
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Impact of Chronic Pain on Use-Dependent Plasticity: Corticomotor Excitability and Motor Representation in Musicians With and Without Pain
Long-term musical training induces adaptive changes in the functional representation of the motor cortex. It is unknown if the maladaptive plasticity...