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Pharmacodynamics: Mechanism of Drug Action
Pharmacodynamics is the study of mechanisms behind drug actions. It helps us understand the behaviour of drugs inside a body and the way body reacts...
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Cancer Therapeutics: Mechanism of Action, Radiation Toxicity, and Drug Formulation
Cancer is a well-known disease that involves complex changes in the genome due to variation in host and environment, and it is also a prime cause of...
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Drug resistance in ovarian cancer: from mechanism to clinical trial
Ovarian cancer is the leading cause of gynecological cancer-related death. Drug resistance is the bottleneck in ovarian cancer treatment. The...
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Drug-Drug and Food-Drug Interactions of Pharmacokinetic Nature
The most relevant pharmacokinetic mechanisms of drug-drug (DD) and food-drug (FD) interactions are summarized from a perspective that will allow the...
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Drug Release
Drug release from dosage forms (also termed drug liberation) is a prerequisite for absorption to occur: only free molecules in solution can cross...
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Drug Excretion
Drug excretion involves processes responsible for physically removing a drug from the body, either unchanged or in the form of biotransformation...
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Drug Absorption
Drug absorption involves the movement of drug molecules from the site of absorption to systemic circulation and is a prerequisite to observe a...
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A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota
BackgroundPharmacomicrobiomics, which has recently emerged as a new strategy for personalized medicine, is the investigation of the influence of...
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Evaluation of Dose-Response Relationship of Permeation Enhancer Isopropyl Myristate Release on Drug Release: Release Enhancement Efficiency and Molecular Mechanism
The objective of this study is to investigate the dose-response relationship between various concentrations of permeation enhancers (PEs) and their...
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Drug Transporters
Membrane transporters play a central role in protecting the body from xenobiotics (either by preventing their absorption, limiting their...
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Molecular mechanism of circRNAs in drug resistance in renal cell carcinoma
Renal cell carcinoma (RCC) is one of the most common malignant tumors with a poor response to radiotherapy and chemotherapy. The advent of molecular...
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Drug Metabolism
Living systems have developed elimination mechanisms to dispose of waste products and protect themselves from exposure to potentially harmful...
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Innovative Drug Delivery Systems for Drug-Resistant Breast Cancer
Breast cancer is the most common and one of the deadliest cancers affecting women worldwide. The mainstay treatment for breast cancer is surgery and...
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Intracellular Compartments and Drug Resistance
Intracellular compartments play a pivotal role in cellular function, housing diverse organelles that contribute to essential processes such as...
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Introduction to Drug Resistance in Cancer
Treating cancer has so many hurdles, and drug resistance is one of them. Treatment strategies are evolving for cancer due to innate and acquired...
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Routes of Drug Administration
The systemic absorption of a drug depends on its physicochemical properties, the nature of the dosage form on which it is included, and the...
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Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement
PurposeTo understand how surfactants affect drug release from ternary amorphous solid dispersions (ASDs), and to investigate different mechanisms of...
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Pulmonary Drug Delivery
This chapter provides an introductory overview on concepts related to drug delivery to the lungs. Physiological barriers to lung delivery are...
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Drug-Induced Tremors
Drug-induced tremors are common in clinical practice, but often underrecognized or misdiagnosed. There are a myriad of drugs that can cause or...
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Drug Development in Psychiatry
The book reviews clinical trial methodology as it pertains to drug development in psychiatry. The reader will understand the process of drug...
