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Forensic Chemistry
Forensic Chemistry applies the principles and techniques of chemical science to forensic analysis of evidences. This includes, but not limited to,...
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Forensic Drug Chemistry: Unravelling Evidence Through Scientific Analysis
Forensic drug chemistry plays a pivotal role in modern criminal investigations by utilising scientific methods to identify, analyse, and interpret...
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Flow Chemistry as an Enabling Technology for Synthetic Organic Chemistry
Continuous-flow processing is proving to be an enabling technology for synthetic organic chemists. After an introduction to the advantages and...
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The Chemistry of Human Exposure to Aluminum
Before it is possible to begin to understand the chemistry of human exposure to aluminum, it is necessary to appreciate a few basic rules. Rule...
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Utilizing mechanistic organic chemistry training to study drug metabolism in preclinical drug discovery/development
A fundamental knowledge of applied organic chemistry is an important weapon in the arsenal of drug metabolism scientists, particularly ones engaged...
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Bibliometric comparison of Nobel Prize laureates in physiology or medicine and chemistry
The Nobel Prize is an annual honor awarded to the researchers who have made the greatest contribution to humanity with their work in the year in...
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Deep Learning and Computational Chemistry
Within the context of the latest resurgence in the application of artificial intelligence approaches, deep learning has undergone a renaissance over...
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Lecture 2: Review of Chemistry
Most matter is usually “impure”, being a mixture of variable amounts of several different substances.
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Inspirational chemistry of bioabsorbable long-acting injectables
Long-acting injectables (LAIs) have made a tremendous impact on clinical medicine. As evidence, dozens of approved LAI products are on the market....
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A review on the synthesis of bio-based surfactants using green chemistry principles
ObjectivesWith increasing awareness of the potential adverse impact of conventional surfactants on the environment and human health, there is...
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Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or...
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Chemistry and Function of Glycosaminoglycans in the Nervous System
Proteoglycans, and especially their GAG components, participate in numerous biologically significant interactions with growth factors, chemokines,...
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Mitsunobu Reactions in Medicinal Chemistry and Development of Practical Modifications
The Mitsunobu reaction is widely used in synthetic chemistry and has contributed to the discovery and scalable synthesis of drugs because the...
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Modulation of cellular transcriptome and proteome composition by azidohomoalanine—implications on click chemistry–based secretome analysis
AbstractThe analysis of the secretome provides important information on proteins defining intercellular communication and the recruitment and...
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Prostacyclin (PGI2) scaffolds in medicinal chemistry: current and emerging drugs
Prostacyclin (PGI 2 ) is a natural hormone that has primarily been explored for its potent vasodilation activity and inhibition of platelet...
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Multicomponent Synthesis: Cohesive Integration of Green Chemistry Principles
The application of multicomponent reactions (MCRs) in the generation of compound libraries has long been recognized as a key strategy for the...
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Development and Validation of Matrix of Chemistry, Manufacturing, and Control (MoCMC) System for Intramammary Drug Products (IMM)
PurposeProducts formulated for intramammary (IMM) infusion are intended for the delivery of therapeutic moieties directly into the udder through the...
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Isoflavones of Soy: Chemistry and Health Benefits
Nutrients impart an essential role in the prevention of various diseases. The biological activity of plant derived compounds allows their use to...
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Free Radical Chemistry of Carotenoids and Oxidative Stress Physiology of Cancer
The role of carotenoids on reducing vitamin A deficiency and cardiovascular and age-related degenerative diseases has been addressed in the last...