Abstract
Forensic Chemistry applies the principles and techniques of chemical science to forensic analysis of evidences. This includes, but not limited to, seized drug analysis, alcohol analysis, fire debris, and post-blast residue analysis and other analysis wherein the chemical identity of material is explored to strengthen its evidentiary significance. Though the field of Forensic is fascinating, it is challenging as well. For instance, changes and destruction brought by fire and explosion incidents often make it difficult for an investigator to classify whether the cause of the incident was accidental or intentional. However, by applying thoughtful analytical processes and using science involved in the fire and explosion process, origin and cause of incident can be apprehended. Accordingly, this chapter focuses on investigative aspects of fire and explosion scenes and analytical approaches followed by an investigation. In addition, testing for drugs and alcohol has become a routine part of forensic chemists over the past few decades as their abuse has been the cause of many violent as well as non-violent crimes. Therefore, the fundamentals of the analytical approach applied in their detection and identification have also been discussed in this chapter.
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References
Agrawal JP (2010) High energy materials: propellants, explosives and pyrotechnics. Wiley-VCH, Weinheim
Akhavan J (2011) The chemistry of explosives. Royal Society of Chemistry, London. https://doi.org/10.1007/978-1-4612-0589-0_5
Almirall JR, Furton KG, Bruna JC (1995) A novel method for the analysis of gasoline from fire debris using headspace solid-phase microextraction. J Forens Sci 41(1):12–22
Almog J, Zitrin S (2009) Colorimetric detection of explosives. In: Aspects of explosives detection. Elsevier, Amsterdam, pp 41–58. https://doi.org/10.1016/B978-0-12-374533-0.00004-0
Baker PB, Phillips GF (1983) The forensic analysis of drugs of abuse. Analyst 108:777
Baquiran M, Khalilili A (2021) Lysergic acid diethylamide toxicity. StarPearls Publishing, Treasure Island, FL
Barth R, Benvenuto MA (2015) Ethanol and education: alcohol as a theme for teaching chemistry. American Chemical Society, Washington, DC. https://doi.org/10.1021/bk-2015-1189.ch001
Battle BP, Weston PB (1954) Arson: a handbook of detection and investigation. Arco Publishing Co, New York, NY
Belitz HD, Grosch W, Schieberle P (2009) Alcoholic beverages. In: Food chemistry. Springer, New York, NY, pp 892–937
Bell S (2014) Forensic chemistry. Pearson, London
Bennett GD (1958) The arson investigation and technical aids. J Crim Law Criminol Police Sci 49:172–177
Bischoff M (1938) La police scientifique. Payot, Paris
Boghdadi MS, Henning RJ (1997) Cocaine: pathophysiology and clinical toxicology. Heart Lung J Acute Crit Care 26(6):466–483. https://doi.org/10.1016/S0147-9563(97)90040-6
Bumbrah GS, Sarin RK, Sharma RM (2016) Derivative ultraviolet spectrophotometry: a rapid, screening tool for the detection of petroleum products residues in fire debris samples. Malay J Forens Sci 7(1):17–26
Cacho JF, Lopez R (2005) Food and nutritional analysis: alcoholic beverages. In: Encyclopedia of analytical science. Elsevier, London, pp 285–291. https://doi.org/10.1016/B0-12-369397-7/00181-3
Cohen K, Weizman A, Weinstein A (2019) Positive and negative effects of cannabis and cannabinoids on health. Clin Pharmacol Ther 105(5):1139–1147. https://doi.org/10.1002/cpt.1381
Couper FJ (2016) Substance misuse. Encycl Forens Legal Med 4:418–421. https://doi.org/10.1016/B978-0-12-800034-2.00358-X
Daeid NN (2004) Fire investigation. CRC Press, Boca Raton, FL
Darsigny C, Leblanc-Couture M, Desgagne-Penix I (2018) Forensic chemistry of alkaloids: presumptive color test. Austin J Forens Sci Criminol 5(1):1–9
Dasgupta A (2019) Alcohol: pharmacokinetics, health benefits with moderate consumption and toxicity. In: Critical issues in alcohol and drugs of abuse testing, 2nd edn. Elsevier, London, pp 1–16. https://doi.org/10.1016/B978-0-12-815607-0.00001-0
Dasgupta A, Wahed A (2014) Testing for ethyl alcohol(alcohol) and other volatiles. In: Clinical chemistry, immunology and laboratory quality control. Elsevier, London, pp 317–335. https://doi.org/10.1016/B978-0-12-407821-5.00018-8
Davy EW (1876) On a new chemical test for alcohol. Proc Roy Irish Acad Sci 2:579–582. https://www.jstor.org/stable/20490026
Day L, McSweeney PLH (2016) Beverages. Reference module in food science. Elsevier, London, pp 1–5. https://doi.org/10.1016/b978-0-08-100596-5.03409-0
Decuyper II, Armentia A, MartÃn-Armentia B, Almuzara AC, Ebo DG, Brucker HA (2021) Adverse reactions to illicit drugs (marijuana, opioids, cocaine) and alcohol. J Allergy Clin Immunol Pract 9(8):3006–3014. https://doi.org/10.1016/j.jaip.2021.04.061
DeTata D (2018) Forensic sciences - arson residues. In: Encyclopedia of analytical science, 3rd edn. Elsevier Inc, London. https://doi.org/10.1016/B978-0-12-409547-2.14450-6
Duke FR, Smith GF (1940) Rapid qualitative test for alcoholic hydroxyl group: use of nitrato and perchlorato cerate anions as test reagents. Ind Eng Chem Anal Ed 12(4):201–203. https://doi.org/10.1021/ac50144a008
Fisher BAJ, Fisher DR (2012) Techniques of crime scene investigation, 8th edn. CRC Press, Boca Raton, FL
Fitzgerald KT, Bronstein AC, Newquist KL (2013) Marijuana poisoning. Top Compan Anim Med 28(1):8–12. https://doi.org/10.1053/j.tcam.2013.03.004
Fleckenstein AE, Volz TJ, Riddle EL, Gibb JW, Hanson GR (2007) New insights into the mechanism of action of amphetamines. Annu Rev Pharmacol Toxicol 47:681–698. https://doi.org/10.1146/annurev.pharmtox.47.120505.105140
Gahlinger P (2004) Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine. Am Fam Physician 69:2619–2626
Gallignani M, Garrigues S, De La Guardia M (1993) Direct determination of ethanol in all types of alcoholic beverages by near-infrared derivative spectrometry. Analyst 118(9):1167–1173. https://doi.org/10.1039/AN9931801167
Gracia JI, Dobado JA, Flores C, Gracia HM (2016) Functional group analysis. In: Experimental organic chemistry: laboratory manual. Academic Press, London. https://doi.org/10.1016/B978-0-12-803893-2.50006-1
Granados JJQ, Samaniego-Sánchez C, Blanca-Herrera RM (2016) Rhum-Ron-Rum: technology and tradition. In: Encyclopaedia of food and health. Elsevier, London, pp 618–627. https://doi.org/10.1016/B978-0-12-384947-2.00598-5
Green B, Kavanagh D, Young R (2003) Being stoned: a review of self-reported cannabis effects. Drug Alcohol Rev 22(4):453–460. https://doi.org/10.1080/09595230310001613976
Heal DJ, Smith SL, Gosden J, Nutt DJ (2013) Amphetamine, past and present – a pharmacological and clinical perspective. J Psychopharmacol 27(6):479–496
Heard BJ (2008) Handbook of firearms and ballistics, 2nd edn. Wiley Blackwell, London
Hine G (2004) Fire scene investigation. CRC Press, Boca Raton, FL. https://doi.org/10.1201/9780203492727.ch2
Ho IK, Harris RA (1981) Mechanism of action of barbiturates. Annu Rev Pharmacol Toxicol 21:83–111
Holper RB (2012) The history, development, and characteristics of explosives and propellants. In: Forensic investigation of explosion, 2nd edn. Routledge, London, pp 1–18
Hwang KAJ, Saadabadi A (2021) Lysergic acid diethylamide (LSD). StarPearls Publishing, Treasure Land, FL. https://www.ncbi.nlm.nih.gov/books/NBK482407/?report=classis
Inman K, Rudin N (2001) Principles and practice of criminalistics: the profession of forensic science. CRC Press, Boca Raton, FL
Jacobsen D, McMartin KE (1996) Alcohols and glycols. In: Descotes J (ed) Human toxicology. Elsevier Science, London. https://doi.org/10.1016/j.mpmed.2015.12.001
Jaiswal YS, Williams LL (2016) A glimpse of Ayurveda – the forgotten history and principles of Indian traditional medicine. J Tradit Complement Med 7(1):50–53. https://doi.org/10.1016/j.jtcme.2016.02.002
Jones AW (2016) Alcohol: breath analysis. In: Encyclopedia of forensic and legal medicine, vol 1. Elsevier, London, pp 119–137. https://doi.org/10.1016/B978-0-12-800034-2.00011-2
Karch SB (1998) Drug abuse handbook. CRC Press, Boca Raton, FL
Kaur N, Byard RW (2020) Bride burning: a unique and ongoing form of gender-based violence. J Forensic Legal Med 75(126):102035. https://doi.org/10.1016/j.jflm.2020.102035
Khan JI, Kennedy TJ, Christian DR (2012) Basic principles of Forensic Chemistry. Humana Press, Totowa, NJ
Kumar D, Elias AJ (2019) The explosive chemistry of nitrogen: a fascinating journey from 9th century to the present. Resonance 24(11):1253–1271. https://doi.org/10.1007/s12045-019-0893-2
Kunkee RE (2002) Wine. Wiley-VCH, Weinheim. https://doi.org/10.1002/14356007.a28269
Lauren J (2013) Opium. Postgrad Med J 89:491–492. https://doi.org/10.1136/postgradmedj-2013-132218
Lentini JJ (2012) Analysis of fire debris. In: Forensic chemistry handbook, 1st edn. Wiley-VCH, Weinheim, pp 41–108
Lentini JJ (2013) Fire patterns and their interpretation. In: Encyclopedia of forensic sciences. Elsevier, London. https://doi.org/10.1016/B978-0-12-382165-2.00213-0
Lentini JJ (2018) Scientific protocols for fire investigation. In: Scientific protocols for fire investigation, 3rd edn. Taylor and Francis, New York, NY. https://doi.org/10.4324/9781315178097
Martin B, Szara S (1998) Marijuana. In: Clinical management of poisoning and drug overdose, 3rd edn. Elsevier, London, pp 528–541
Martinez MA, Ballesteros S (2019) Opium poisoning in modern times: an overview. Forensic Sci Int 302:109848. https://doi.org/10.1016/jforsciint.2019.06006
Matthew H (1975) Barbiturates. Clin Toxicol 8(5):495–513
Mohanty B (2012) Physics of explosion hazard. In: Forensic investigation of explosion, 2nd edn. Routledge, London, pp 19–52
Myren RA (1954) Investigation of arson and other unlawful burnings. Institute of Government, The University of North Carolina
NIH (2020) Opioids. National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD. https://www.ncbi.nlm.nih.gov/books/
Passie T, Halpern JH, Stichtenoth DO, Emrich HM, Hintzen A (2008) The pharmacology of lysergic acid diethylamide: a review. CNS Neurosci Ther 14(4):295–314. https://doi.org/10.1111/j.1755-5949.2008.00059.x
Rabinowitz H, Vogel S (2009) Style and usage for organic chemistry. In: The manual of scientific style. Elsevier, London, pp 399–425. https://doi.org/10.1016/b978-012373980-3.50014-9
Rao LJM, Ramalakshmi K (2011) Introduction to soft drinks, Recent trends in soft drinks. Woodhead Publishing, New Delhi. https://doi.org/10.1533/9780857093653.3.177
Reddy VR (2016) Neuropathy of drug addiction and substance misuse, 2nd edn. Academic Press, London
Reiss RA (1911) Manuel de police scientifique (technique) - I Vols et homicides. Librairie Payot and Cie, Paris
Rojas SF, Bosch Ojeda C (2008) Recent development in derivative ultraviolet/visible absorption spectrophotometry: 2004–2008: a review. Anal Chim Acta 635(1):22–44. https://doi.org/10.1016/j.aca.2008.12.039
Rudin N, Inman K (2002) Forensic science timeline. http://www.forensicdna.com.Tiemline020702.pdf
Saadat F, Rafizadeh A (2019) Rapid determination of methanol in herbaceous distillates for their safety evaluation by a new modified chromotropic acid method. Iran J Pharmaceut Res 18(2):696–703. https://doi.org/10.22037/ijpr.2019.1100661
Sachs J, McGlade E, Yurgelun-Todd D (2015) Safety and toxicology of cannabinoids. Neurotherapeutics 12(4):735–746. https://doi.org/10.1007/s13311-015-0380-8
Sadler PJ (1950) The crime of arson. J Crim Law Criminol 41(3):290–305
Saferstein R (2013) Forensic science - from crime scene to the crime lab, 2nd edn. Pearson, London
Sampat AAS, Van Daelen B, Lopatka M, Mol H, Van Derweg G, Truyols GV, Sjerps M, Schoenmakers PJ, Asten ACV (2018) Detection and characterization of ignitable liquid residues in forensic fire debris samples by comprehensive two-dimensional gas chromatography. Separations 5(3):1–27. https://doi.org/10.3390/separations5030043
Schaeffer HF (1942) The iodoform reaction by methods of microscopy. J Chem Educ 19(1):15–16. https://doi.org/10.1021/ed019p15
Siegel J, Knupfer G, Saukko P (2013a) Drugs of abuse. In: Encyclopedia of forensic science, 2nd edn. Academic Press, London, pp 598–626
Siegel J, Saukko PJ, Houck MM (2013b) Encyclopedia of forensic sciences, 2nd edn. Academic Press, London, pp 579–585
Siegrist M, Wiegand TJ (2014) Cocaine. Encyclopedia of toxicology, vol 1, 3rd edn. Academic Press, London, pp 999–1002. https://doi.org/10.1016/B978-0-12-386454-3.00715-6
Singh GPS (2020) Date rape drugs in sexual assault: a threat to Indian society. Eur J Mol Clin Med 7:4677
Sleigh J, Harvey M, Voss L, Denny B (2014) Ketamine - more mechanisms of action than just NMDA blockade. Trends Anaesth Crit Care 4(2–3):76–81. https://doi.org/10.1016/j.tacc.2014.03.002
Smith FP (2005) Forensic drug analysis. Academic Press, London
Stauffer E, Dolan JA, Newman R (2008) Fire debris analysis. Academic Press, London
Stowell A (2013) Blood-alcohol. In: Encyclopedia of forensic sciences, 2nd edn. Academic Press, London. https://doi.org/10.1016/B978-0-12-382165-2.00294-4
Stuart B (2013) Forensic analytical techniques. John Wiley and Sons, New York, NY
Sturaro A, Vianello A, Denti P, Rella R (2013) Fire debris analysis and scene reconstruction. Sci Justice 53:201–205. https://doi.org/10.1016/j.scijus.2012.08.002
Sunshine I, Hodnett N (1971) Methods for the determination of ethanol and acetaldehyde. The biology of alcoholism. Springer, New York, NY, pp 545–573. https://doi.org/10.1007/978-1-4615-6525-3_16
Tamiri T, Zitrin S (2013) Explosives: analysis. In: Encyclopaedia of forensic sciences, 2nd edn. Academic Press, London. https://doi.org/10.1016/B978-0-12-382165-2.00083-0
Thatcher PJ (2000) Chemistry of fire. In: Encyclopedia of forensic sciences, vol 1. Academic Press, London, pp 900–905
Turner RF (1949) Forensic science and laboratory technics. Charles C. Thomas, Springfield, IL
UNODC (2021) Pandemic effect ramp up drug risks, as youth underestimate cannabis dangers. World drug Report. UNODC, Vienna. https://wdr.unodc.org/
Vermette JY (2012) General protocols at the scene of an explosion. In: Forensic investigation of explosions, 2nd edn. Routledge, London, pp 80–95
Walker JRL (1992) Spectrophotometric determination of enzyme activity: alcohol dehydrogenase (ADH). Biochem Educ 20:42
Walker GM (2009) Yeasts. In: Encyclopedia of microbiology. Academic Press, London. https://doi.org/10.1016/B978-012373944-5.00335-7
Wallace JS (2018) Chemical analysis of firearms, ammunition, and Gunshot residue. CRC Press, Boca Raton, FL
White P, Emerson V (2004) Alcohol. In: From crime scene to court: the essential of forensic science, 2nd edn. RSC, London, pp 350–376. https://doi.org/10.1039/9781847550651-00350
Wigmore JG (2013) Breath alcohol. In: Encyclopedia of forensic sciences, 2nd edn. Academic Press, London, pp 313–317. https://doi.org/10.1016/B978-0-12-382165-2.00296-8
Wiley HW, Tolman LM, Bryan AH (1910) Manufacture of denatured alcohol. U.S. Govt. Printing Office, Washington, DC
Yadav PK, Sharma RM (2019) Classification of illicit liquors based on their geographic origin using Attenuated total reflectance (ATR) – Fourier transform infrared (FT-IR) spectroscopy and chemometrics. Forensic Sci Int 295:e1–e5. https://doi.org/10.1016/j.forsciint.2018.12.017
Yadav VK, Nigam K, Srivastava A (2020) Forensic investigation of arson residue by infrared and Raman spectroscopy: from conventional to non-destructive techniques. Med Sci Law 60(3):206–215. https://doi.org/10.1177/0025802420914807
Zanos P, Gould TD (2018) Mechanisms of ketamine action as an antidepressant. Mol Psychiatry 23(4):801–811. https://doi.org/10.1038/mp.2017.255
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Yadav, V.K., Kumar, A., Shahid, S., Nigam, K., Srivastava, A. (2023). Forensic Chemistry. In: Shrivastava, P., Lorente, J.A., Srivastava, A., Badiye, A., Kapoor, N. (eds) Textbook of Forensic Science . Springer, Singapore. https://doi.org/10.1007/978-981-99-1377-0_22
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